Gum Acacia Modified Ni Doped CuO Nanoparticles: An Excellent Antibacterial Material

Dwivedi, Lalit Mohan; Shukla, Neelam; Baranwal, Kirti; Gupta, Shipra Sen; Siddique, Shehala; Singh, Vandana

doi:10.1007/s10876-020-01779-7

Cited by 26 publications

(7 citation statements)

References 56 publications

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“…Why the gum Arabic is used as a moderating agent to prepare AgNPs is because GA exerts its components over NPs as capping agents change Zeta potential to negative and causes aggregation process [ 16 ]. Using GA as a growth medium for nickel nanoparticle preparation enhances excellent antibacterial behaviour [ 17 ]. Further GA exuded from A. senegal was proved to be an immunomodulatory agent in COVID-19 patients [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of silver nanoparticles using gum Arabic: Evaluation of its inhibitory action on Streptococcus mutans causing dental caries and endocarditis

Al-Ansari

Al-Dahmash

Ranjitsingh³

2021

Journal of Infection and Public Health

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Background Streptococcus mutans are an oral pathogen that causes dental caries, endocarditis, and systemic dysfunctions, an alternative antibacterial solution from silver nanoparticles (AgNPs) are investigated. Methods AgNPs were synthesized using the ethnobotanical product gum Arabic. It influenced the nanoparticles with medicinal value through their role as capping, stabilizing, or surface-attached components. The biophysical characteristics of the synthesized AgNPs were studied using UV–vis spectrum, XRD, EDAX, SEM, and TEM tools. The AgNPs were spherical with the average size less than 10 nm. By using the well diffusion and microdilution techniques, the impact of synthesized AgNPs was tested against S. mutans isolates. Results The smaller the size, the greater the antibacterial and antiviral potential the particles exhibit. The biophysical characteristics of AgNPs the presence of phenols, alcohols, amides, sulfoxide, flavanoids, terpenoids and steroids. The AgNPs exhibited a good antibacterial action against the oral pathogen S. mutans. The synthesized NPs at a dose level of 200 μg/mL exhibited an inhibition zone with 18.30 ± 0.5 nm diameter. The synthesised nanoparticles inhibited the genes responsible for biofilm formation of S. mutans over host tooth and gums (gtfB, gtfc, gtfD) and virulent protective factors (comDE, brpA and smu 360) and survival promoter genes (gyrA and spaP, gbpB). Conclusion The potent antibiotic action over S. mutans seen with the synthesized NPs, paves the way for the development of novel dental care products. Also, the small-sized NPs promote its applicability in COVID-19 pandemic containment.

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Section: Introductionmentioning

confidence: 99%

Synthesis of silver nanoparticles using gum Arabic: Evaluation of its inhibitory action on Streptococcus mutans causing dental caries and endocarditis

Al-Ansari

Al-Dahmash

Ranjitsingh³

2021

Journal of Infection and Public Health

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“…What's more, the growth medium also has some influence on antimicrobial activity. Dwivedi et al 105 synthesized Ni 0.1 Cu‐GA antibacterial materials by using gibberellin (GA) of different concentrations as a growth medium. GA is an acidic polysaccharide with carboxyl functional groups, which produce additional oxygen vacancies to produce extra free radicals.…”

Section: Fight Arb With Alternative Weaponsmentioning

confidence: 99%

Nanofibrous dressing: Potential alternative for fighting against antibiotic‐resistance wound infections

Yingjie

Zhang

et al. 2022

J of Applied Polymer Sci

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The progression of antibiotic‐resistant bacteria (ARB) as well as impaired immunity due to chronic diseases and complications, aging, and so forth pose opportunities in parallel with challenges to the wound dressing products. In a bid to address the remedies, electrospun nanofibrous membranes (ENMs) with high permeability and good biocompatibility have made an entry as wound dressings. With high specific surface area, such ENMs can pave the way for the loading and release of antimicrobial agents and further promote wound healing by mimicking the extracellular matrix structure. In this review, we have compiled a series of novel antimicrobial agents that can be substituted for antibiotics against ARB and outlined their antimicrobial mechanisms, providing an overview of the latest research to illustrate how ENMs can achieve the loading and efficient release of antimicrobial agents against ARB. Last but not least, on the basis of the demands for timely and accurate wound diagnosis, ENMs capable of colorimetric detection are featured as test‐strips for the diagnosis of wound pathogenic bacteria, in the hope of inspiring researchers to design smart wound dressings capable of diagnosis and treatment integration.

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“…Gum acacia, a complex polysaccharide extracted from certain trees of the genus Acacia was reported as a stabilizing agent in the generation of nickel-doped copper oxide nanoparticles (Ni 0.1 CuO) (size average, 12 nm) by Singh et al [160] who then examined the antibacterial activity of these nanocomposites against various pathogenic bacteria, namely Enterobacter, Klebsiella pneumoniae, P. aeruginosa and S. aureus. It was reported that this nanocomposite generated wider zones of inhibition than the commonly used antibiotic ampicillin and the same nanoparticles without gum acacia coating both with and without nickel doping.…”

Section: Biologic Polymer/magnetic Nanocompositesmentioning

confidence: 99%

Recent Advances in Magnetic Nanoparticles and Nanocomposites for the Remediation of Water Resources

Govan

2020

Magnetochemistry

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Water resources are of extreme importance for both human society and the environment. However, human activity has increasingly resulted in the contamination of these resources with a wide range of materials that can prevent their use. Nanomaterials provide a possible means to reduce this contamination, but their removal from water after use may be difficult. The addition of a magnetic character to nanomaterials makes their retrieval after use much easier. The following review comprises a short survey of the most recent reports in this field. It comprises five sections, an introduction into the theme, reports on single magnetic nanoparticles, magnetic nanocomposites containing two of more nanomaterials, magnetic nanocomposites containing material of a biologic origin and finally, observations about the reported research with a view to future developments. This review should provide a snapshot of developments in what is a vibrant and fast-moving area of research.

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Gum Acacia Modified Ni Doped CuO Nanoparticles: An Excellent Antibacterial Material

Cited by 26 publications

References 56 publications

Synthesis of silver nanoparticles using gum Arabic: Evaluation of its inhibitory action on Streptococcus mutans causing dental caries and endocarditis

Synthesis of silver nanoparticles using gum Arabic: Evaluation of its inhibitory action on Streptococcus mutans causing dental caries and endocarditis

Nanofibrous dressing: Potential alternative for fighting against antibiotic‐resistance wound infections

Recent Advances in Magnetic Nanoparticles and Nanocomposites for the Remediation of Water Resources

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