Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults

Economic Evaluation and Budget Impact Analysis of the Surveillance Program for Hepatocellular Carcinoma in Thai Chronic Hepatitis B Patients

“…Therefore, both CHB males and females aged between 40-50 years would be recommended to receive HCC surveillance. The recommendations from our study are in accordance with Thai clinical practice guidelines (National Cancer Institute-Ministry of Public Health, 2011) which adopted the concept of screening and surveillance from World Health Organization (WHO) criteria and other guidelines (Ryder, 2003, Meissner, et al, 2004. Thai clinical practice guidelines have recommended that CHB patients with no cirrhosis who are males aged more than 45 years or females aged more than 50 years are recommended to be screened for HCC every six months.…”

Long-term Prognosis in Hepatocellular Carcinoma Patients after Hepatectomy

“…Recently, most studies identify the risk factors for HCC patients' prognosis main from four facts: degree of liver damage, tumor characteristic, surgical-related elements and the adjuvant therapy after operation (Ryder, 2003;Schiffman et al, 2010). In the univariate analysis for the current study, 7 of 22 factors showed significant differences; and the multivariate analysis, which was stratified by associated liver disease, found that 2 tumor factors (tumor size and hepatic vein invasion) and 2 clinical factors (status of liver cirrhosis and GGT level) were independent prognostic factors for overall survival.…”

“…The adjuvant therapies after operation include DDS (drug delivery system), TACE (transcatheter arterial chemoembolization) and so on. The classification of surgical modes, (1) Pathologically curative resection: no more than 2 tumor nodules intrahepatic and no (Ryder, 2003). TNM stage use the latest six edition made by UICC/AJCC.…”

The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines from 2001 to 2017

“…In line with the criteria above, 18 guidelines that were published between 2001 and 2017 were identified for analysis, including 8 guidelines from Asia, 5 from Europe, and 5 from the United States of America (USA) ( Table 1) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28). These 18 characteristic guidelines were examined with a focus on the clinical management of HCC, and surveillance, diagnosis, and treatment in those guidelines were compared.…”

“…For nodules > 2 cm, a hallmark detected by 1 imaging technique would be sufficient (39). The 2010 version of the AASLD Guideline updated criteria as: an imaging technique revealing a radiological hallmark of HCC is sufficient for diagnosis of tumors 1-2 cm in diameter (19). However, the Chinese Guideline still include AFP ≥ 400 for 1 month or ≥ 200 for 2 months as a diagnostic criterion for nodules 1-2 cm in size (12).…”