Guidelines for pregnant individuals with monkeypox virus exposure

Monkeypox

“…In Central and West Africa, severe and even fulminant cases in children have been well described, 1 and are likely under‐reported due to difficulties with access to health‐care services and to monkeypox‐specific diagnostic tools. There are reports of fetal loss from monkeypox contracted in the first trimester, and advice has been published in the United Kingdom on the management of pregnant women with monkeypox or those who have been exposed to cases 5,6 . Smallpox vaccines provide some protection as post‐exposure prophylaxis against monkeypox, and some countries are instituting smallpox vaccination for people at occupational risk of exposure to monkeypox.…”

“…There are reports of fetal loss from monkeypox contracted in the first trimester, and advice has been published in the United Kingdom on the management of pregnant women with monkeypox or those who have been exposed to cases. 5,6 Smallpox vaccines provide some protection as postexposure prophylaxis against monkeypox, and some countries are instituting smallpox vaccination for people at occupational risk of exposure to monkeypox. However, there are challenges with vaccine availability in many settings, with only replicationcompetent vaccines (which have a high number of potential adverse effects) available in some countries.…”

The emergence of new lineages of the Mpox virus could affect the 2022 outbreak

“…The copyright holder for this preprint this version posted July 7, 2022. ; https://doi.org/10.1101/2022.07.07.498743 doi: bioRxiv preprint in certain population groups as immunosuppressed persons, young children and pregnant women (Di Giulio and Eckburg, 2004). Even if there are few data linking pregnant women and the effects of human Monkeypox virus infection, there is evidence that viruses of the Orthopoxvirus genus are associated with an increased risk of maternal and perinatal morbidity and mortality (Dashraath et al, 2022;Khalil et al, 2022;Mbala et al, 2017).…”

“…Although most cases in current outbreaks have presented with mild disease symptoms, Monkeypox virus may cause severe disease in certain population groups as immunosuppressed persons, young children and pregnant women (Di Giulio and Eckburg, 2004). Even if there are few data linking pregnant women and the effects of human Monkeypox virus infection, there is evidence that viruses of the Orthopoxvirus genus are associated with an increased risk of maternal and perinatal morbidity and mortality (Dashraath et al, 2022; Khalil et al, 2022; Mbala et al, 2017). Understanding how virulence evolves after a virus jumps or adapts to a new host species is critical to the effective prevention and treatment of viral infections.…”

MonkeyPox2022Tweets: The First Public Twitter Dataset on the 2022 MonkeyPox Outbreak

“…The recent outbreak of monkeypox has also led to an increase in research and development in this field. These include -a study on the outbreaks in Europe and North America [58], an analysis of stigmatization of the LGBTQI+ community due to the outbreak [59], studying the increasing cases in England [60], research on monkeypox image data [61], investigating methods of transmission of the virus through sexual contact [62], analyzing public attitude towards monkeypox [63], predicting the burden and duration of this outbreak [64], use of the Jynneos vaccine for preexposure vaccination of people at risk for occupational exposure [65], nanopore sequencing of a monkeypox virus strain [66], studying the incubation period [67], guidelines for pregnant individuals with monkeypox virus exposure [68], attitudes of the US general public towards monkeypox [69], a rapid metagenomic method to detect emerging viral pathogens applied to human monkeypox [70], and information that dermatologists need to know regarding this outbreak [71].…”