Guidelines for Pre-Transfusion Compatibility Procedures in Blood Transfusion Laboratories in Japan (2nd Edition)

誠, 奥田; 健, 石丸; 誠, 内川; 道子, 梶原; 淳一, 北澤; 晃, 国分寺; 信昌, 小林; 典久, 小山; 智哉, 髙橋; 明裕, 竹下; 広康, 安田

doi:10.3925/jjtc.62.651

Cited by 10 publications

(1 citation statement)

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“…In order to investigate whether there are any beneficial effects of more frequent screening, with respect to alloantibody detection and frequency of DHTR, this retrospective, single-center, observational study was performed. In 2016, the Japan Society of Blood Transfusion and Cell Therapy advised that patients previously transfused or pregnant within the previous 3 months, should be cross-matched using samples no more than 3 days old at the time of transfusion [12].…”

Section: Discussionmentioning

confidence: 99%

Shortened antibody screening interval has decreased the incidence of delayed hemolytic transfusion reactions

Takano¹,

Yasuda²,

Kikuchi³

et al. 2018

Int J Blood Transfus Immunohematol

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Aims: To ascertain the effects of allowable sampling time prior to red cell transfusion when screening for alloantibodies, we compared antibody detection rates and frequencies of delayed hemolytic transfusion reactions (DHTRs) among patients drawn within two weeks versus patients drawn within one week of transfusion. Methods: Alloantibody screening for 32,601 patients from January 1997 through August 2006 was done within two weeks of transfusion, and for 44,896 patients from September 2006 through March 2017 was done within one week. Among transfusion recipients, 6,234 screened within two weeks and 8,066 screened within one week were evaluated for DHTR. Results: Alloantibodies were detected in 1.2% of cases screened within two weeks and in 1.3% of cases

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Section: Discussionmentioning

confidence: 99%

Shortened antibody screening interval has decreased the incidence of delayed hemolytic transfusion reactions

Takano¹,

Yasuda²,

Kikuchi³

et al. 2018

Int J Blood Transfus Immunohematol

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Retrospective study about the frequency of irregular antibodies and the importance of those measurements in critically ill patients

Akazawa

Fukushima

Yogoro

et al. 2020

Nihon Shuchu Chiryo Igakukai zasshi

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Irregular antibodies are non-ABO alloantibodies that can cause hemolytic disease in fetuses and newborns, reduced red cell survival, and delayed hemolytic transfusion reaction (DHTR). DHTR may present with intravascular hemolysis and associated findings, including death. However, little is known about the frequency of irregular antibodies in critically ill patients. Methods: We used an electronic clinical transfusion management system to retrospectively assess all patients who underwent irregular antibody screening between January 2012 and November 2015. We collected information about age, sex, transfusion history, and type of irregular antibodies. Results: Screening for irregular antibodies revealed that 14 (1.8%) of 770 patients (male, n=11; female, n=3; mean age [ ± SD], 64.0 ± 14.7 years) harbored irregular antibodies. Ten patients (1.3%) had clinically significant warm antibodies. Five patients had a history of transfusion and four did not. Information about transfusion was unavailable for the remaining five due to varying circumstances such as patient unconsciousness. Conclusion: Patients with irregular antibodies are not rare, and 14 (1.8%) of 770 patients in our ICU had them. As the history of transfusion in critically ill patients is often unknown, side effects of transfusion can be serious. Therefore, repeating irregular antibodies tests proactively may prevent side effects of transfusion, including DHTR.

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The Effects of a Practical Skills and Refresher Workshop on Pre-Transfusion Testing for Clinical Technologists Working at Small or Medium-Sized Hospitals

Oda¹,

Higashitani²,

Ishii³

et al. 2018

JJTC

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Guidelines for Pre-Transfusion Compatibility Procedures in Blood Transfusion Laboratories in Japan (2nd Edition)

Cited by 10 publications

References 0 publications

Shortened antibody screening interval has decreased the incidence of delayed hemolytic transfusion reactions

Shortened antibody screening interval has decreased the incidence of delayed hemolytic transfusion reactions

Retrospective study about the frequency of irregular antibodies and the importance of those measurements in critically ill patients

The Effects of a Practical Skills and Refresher Workshop on Pre-Transfusion Testing for Clinical Technologists Working at Small or Medium-Sized Hospitals

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