Abstract:Irregular antibodies are non-ABO alloantibodies that can cause hemolytic disease in fetuses and newborns, reduced red cell survival, and delayed hemolytic transfusion reaction (DHTR). DHTR may present with intravascular hemolysis and associated findings, including death. However, little is known about the frequency of irregular antibodies in critically ill patients. Methods: We used an electronic clinical transfusion management system to retrospectively assess all patients who underwent irregular antibody scre… Show more
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