Growth study and essential oil analysis of Piper aduncum from two sites of Cerrado biome of Minas Gerais State, Brazil

Oliveira, Gisele; Moreira, Davyson de Lima; Mendes, Aretusa Daniela Resende; Guimarães, Elsie Franklin; Figueiredo, Lourdes Silva de; Kaplan, Maria Auxiliadora Coelho; Martins, Ernane Ronie

doi:10.1590/s0102-695x2013000500005

Cited by 35 publications

(35 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The chemical composition of essential oil from P. aduncum inflorescences has been described by this study for the first time. Specifically, the chemical composition of the essential oil from leaves (PL-EO) was found to be similar to other chemical compositions that had already been reported in the literature regarding other species of P. aduncum from other Brazilian regions (Oliveira et al 2006(Oliveira et al , 2013b.…”

Section: Resultssupporting

confidence: 80%

Essential oils from Piper aduncum inflorescences and leaves: chemical composition and antifungal activity against Sclerotinia sclerotiorum

Valadares

Alves

et al. 2018

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Even though essential oils from Piper aduncum (Piperaceae) have different biological activities, little is known about their application to agricultural areas. White mold is a plant disease caused by the phytopathogen Sclerotinia sclerotiorum, which needs to be controlled by alternative measures. This study aimed at evaluating the effect of essential oils from P. aduncum leaves (PL-EO) and inflorescences (PI-EO) on the mycelial growth of S. sclerotiorum. Essential oils from P. aduncum were obtained by hydrodistillation by a Clevenger-type apparatus while their chemical composition was analyzed by GC-MS and GC-FID. Piperitone (23.4 %), myristicin (12.4 %), terpinen-4-ol (12.3 %), β-caryophyllene (7.2 %), α-humulene (6.9 %), germacrene-D (6.9 %) and dillapiol (6.3 %) were the main constituents found in oils from P. aduncum. The in vitro antifungal activity showed that PI-EO dose above 30 µL inhibited mycelial growth in 100 %, whereas PL-EO at 50 µL inhibited it in 98.74 %. This is the first report of the chemical composition of PI-EO and results suggest that the essential oils under evaluation have high potential to control the phytopathogenic fungus S. sclerotiorum.

show abstract

Section: Resultssupporting

confidence: 80%

Essential oils from Piper aduncum inflorescences and leaves: chemical composition and antifungal activity against Sclerotinia sclerotiorum

Valadares

Alves

et al. 2018

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

show abstract

“…Dentro de los estudios de composición quími-ca y actividad biológica de especies de Piperaceae de origen amazónico, se destacan aquellos realizados en Piper aduncum (Oliveira et al, 2013;Guerrini et al, 2009), en el primera investigación se destaca la presencia de 1,8 cineol y en la segunda de dillapiol, Piper hispidinervum (Sauter et al, 2012) en donde el componente principal es el safrol, Piper auritum (Diego, 2012) cuya molécula mayoritaria es el safrol y se resalta su actividad antifúngica, en Piper holtonii (Diego, 2012) la molécula más abundante es el apiol y se observa una muy buena actividad antifúngica, y Piper divaricatum (Barbosa et al, 2012) en donde se observa un elevado contenido de safrol y una buena actividad antimicrobiana, entre los estudios más importantes.…”

Section: Introductionunclassified

DISTRIBUCIÓN GEOGRÁFICA POTENCIAL DE LA ESPECIE CUNICULUS PACA (Guanta) EN EL OCCIDENTE DE ECUADOR

Noriega

Mosquera

Abad

et al. 2016

lgr

View full text Add to dashboard Cite

Manuscrito recibido el 14 de marzo de 2016. Aceptado, tras revisión, el 12 de octubre de 2016. ResumenPiper pubinervulum C. DC., es una planta medicinal utilizada por los indígenas amazónicos del sur del Ecuador, las hojas poseen características aromáticas. El objetivo de la presente investigación es la de extraer y analizar las propiedades químicas y de actividad biológica del aceite esencial proveniente de las hojas.El estudio de composición química a través de GC-EM y RMN 1 H arrojó la detección de 44 constituyentes dentro de los cuales β cariofileno, isoeugenol-metil éter, asarona y el nerolidol fueron los mayoritarios. La Actividad antioxidante del aceite fue evaluada por los métodos DPPH (1,1-diphenyl-2-picrylhydrazyl), ABTS (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt) y la fotoquimioluminiscencia (PCL). Adicionalmente se realizaron estudios de actividad empleando (HP)TLC-DPPH bioautográficos. La actividad antimicrobiana fue evaluada por el método de difusión de disco en dos bacterias Gram+, dos bacterias Gram-y dos levaduras. Los resultados más interesantes se producen con las dos levaduras Candida tropicalis (MIC 0,77 mg/ml) y Candida albicans (MIC 0,33mg/ml) donde la actividad fue similar al aceite esencial de Thymus vulgaris el estándar natural de referencia. Los buenos resultados con respecto a la actividad antifúngica nos llevan a concluir que el aceite esencial podría ser usado con esta finalidad. AbstractPiper puvinervulum C. DC. is a medicinal plant used by Amazon Indians in southern Ecuador, the leaves possess aromatic characteristics. The objective of this research is to extract and analyze the chemical properties and biological activity of the essential oil from the leaves. The study of the chemical composition based on analysis GC-MS and 1 H RMN data resulted in the identification of 44 compounds including the main components: β-caryophyllene (1), isoeugenol methyl ether (2), asarona (3), and nerolidol (4). The antioxidant potential of the oils was assessed with the DPPH (1,1-diphenyl-2-picrylhydrazyl), ABTS (2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt), Photochemiluminescence and bioautographic HPTLC-DPPH methods. The antimicrobial activity was evaluated by means of disc diffusion method while the antimicrobial effect was evaluated in two Gram+ bacteria, two Gram-bacteria, and two yeasts. The essential oil was found effective against Candida tropicalis (MIC 0,77 mg/ml) and Candida albicans (MIC 0,33mg/ml) yeasts in a manner similar to the reference essential oil of Thymus vulgaris. The positive results in terms of antifungal activity suggest that the essential oil could be used for this purpose.

show abstract

“…cordulatum (GOTTLIEB et al, 1981). However, individuals from this same species collected in other regions have other major constituents, including 1,8-cineole (LARA-JÚNIOR et al, 2012;OLIVEIRA et al, 2013), (E)-nerolidol (MESQUITA et al, 2005;OLIVEIRA et al, 2006) and nerolidol (NAVICKIENE et al, 2006), asaricine (FERREIRA, 2011; POTZERNHEIM et al, 2012) and piperitone ( POTZERNHEIM et al, 2012). Table 5 summarizes the major components found in leaf EOs from P. aduncum L., highlighting the results of studies conducted in Brazil.…”

Section: Discussionmentioning

confidence: 99%

Piper aduncum against Haemonchus contortus isolates: cross resistance and the research of natural bioactive compounds

Gaínza

Fantatto

Chaves

et al. 2016

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

The anthelminthic activity of the essential oil (EO) of Piper aduncum L. was tested in vitro on eggs and larvae of resistant (Embrapa2010) and susceptible (McMaster) isolates of Haemonchus contortus. The EO was obtained by steam distillation and its components identified by chromatography. EO concentrations of 12.5 to 0.02 mg/mL were used in the egg hatch test (EHT) and concentrations of 3.12 to 0.01 mg/mL in the larval development test (LDT). Inhibition concentrations (IC) were determined by the SAS Probit procedure, and significant differences assessed by ANOVA followed by Tukey's test. In the EHT, the IC 50 for the susceptible isolate was 5.72 mg/mL. In the LDT, the IC 50 and IC 90 were, respectively, 0.10 mg/mL and 0.34 mg/mL for the susceptible isolate, and 0.22 mg/mL and 0.51 mg/mL for the resistant isolate. The EO (dillapiole 76.2%) was highly efficacious on phase L 1 . Due to the higher ICs obtained for the resistant isolate, it was raised the hypothesis that dillapiole may have a mechanism of action that resembles those of other anthelmintic compounds. We further review and discuss studies, especially those conducted in Brazil, that quantified the major constituents of P. aduncum-derived EO.Keywords: Isolates, Haemonchus contortus, cross resistance, dillapiole, synergy. ResumoEste estudo avaliou a atividade anti-helmíntica in vitro do óleo essencial (OE) de Piper aduncum L. sobre ovos e larvas de Haemonchus contortus, verificando se um isolado resistente (Embrapa2010), apresentaria o mesmo comportamento que um sensível (McMaster). O OE foi obtido por arraste a vapor e analisado por cromatografia para identificação dos constituintes. O óleo foi avaliado nas concentrações de 12,5 a 0,02 mg/mL no Teste de eclosão dos ovos (TEO) e nas concentrações de 3,12 a 0,01 mg/mL no Teste de desenvolvimento larvar (TDL). As concentrações inibitórias (CI) foram determinadas pelo procedimento Probit do SAS e as diferenças estatísticas geradas pela ANOVA seguida pelo teste de Tukey. Para o isolado sensível obteve-se CI 50 de 5,72 mg/mL no TEO. No TDL o óleo apresentou CI 50 e CI 90 de 0,10 mg/mL e 0,34 mg/mL para o isolado sensível e 0,22 mg/mL e 0,51 mg/mL para o resistente, respectivamente. Demonstrou-se que o OE (dilapiol 76,2%) teve alta eficácia sobre a fase L 1 . Devido às elevadas CIs obtidas para o isolado resistente, levantou-se a hipótese de que o dilapiol talvez possua um mecanismo de ação semelhante a algum grupo anti-helmíntico. O artigo faz uma revisão e discute estudos de quantificação dos constituintes majoritários do OE de P. aduncum, destacando os realizados no Brasil.

show abstract

Growth study and essential oil analysis of Piper aduncum from two sites of Cerrado biome of Minas Gerais State, Brazil

Cited by 35 publications

References 49 publications

Essential oils from Piper aduncum inflorescences and leaves: chemical composition and antifungal activity against Sclerotinia sclerotiorum

Essential oils from Piper aduncum inflorescences and leaves: chemical composition and antifungal activity against Sclerotinia sclerotiorum

DISTRIBUCIÓN GEOGRÁFICA POTENCIAL DE LA ESPECIE CUNICULUS PACA (Guanta) EN EL OCCIDENTE DE ECUADOR

Piper aduncum against Haemonchus contortus isolates: cross resistance and the research of natural bioactive compounds

Contact Info

Product

Resources

About