Growth hormone

Harvey, S.; Hull, Kerry

doi:10.1007/bf02801319

Cited by 76 publications

(10 citation statements)

References 202 publications

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“…The growth performance of fish is controlled by the growth hormone (GH), which is regulated by the Insulin-like growth factor 1 (IGF-1) (Harvey and Hull, 1997;Katoh et al, 1999). The results showed upregulated GH and IGF-1 genes in the livers of tilapia treated with synbiotics.…”

Section: Discussionmentioning

confidence: 99%

Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Magouz

Radwan²,

Soltan

et al. 2023

Annals of Animal Science

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Nile tilapia is recognized as a suitable candidate for intensive farming and sustainability of the aquaculture industry. However, one issue limiting Nile tilapia expansion in arid and semi-arid areas is the scarcity of freshwater resources. In this study, the supplementation of synbiotics was investigated to enhance the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater. Four diets were prepared where the basal diets were mixed with the dietary mixture of probiotics and prebiotics (Synbiotic Lactic Dry ® , a blend of Saccharomyces cerevisiae, Lactobacillus acidophilus, Streptococcus faecium, andBacillus subtilis, mannan oligosaccharides and β-1.3/1.6-D-glucan) at 0, 0.5, 1, and 2 g/kg. After eight weeks, the final weight and weight gain are linearly increasing with increasing the supplementation level of synbiotic. Markedly fish fed 0.5, 1, and 2 g/kg of synbiotic had higher final weight, weight gain, and feed intake and lower feed conversion ratio (FCR) than fish fed synbiotic free diet. The specific growth rate (SGR) was significantly higher in fish fed 1 and 2 g/ kg than in fish fed 0 and 0.5 g/ kg. The intestine of fish fed on synbiotic shows an increase in intestinal villi density. Further, the intestine of fish fed on synbiotic showed an increase in the length and branching intestinal villi (anterior, middle, and posterior) in a dose-dependent manner. The lysozyme and phagocytic activities were significantly different from the control, while synbiotic supplementation did not affect the phagocytic index. Interestingly, the results showed marked upregulation of ghrelin, IGF-1, and GH genes in fish fed synbiotics at 0.5, 1, and 2 g/kg. In addition, fish fed 2 g/kg had the highest expression of ghrelin, IGF-1, and GH genes. In conclusion, growing Nile tilapia in inland brackish groundwater can be achieved without negative impacts on the growth performance and health status. Supplementing synbiotics (1-2 g/kg) in Nile tilapia feeds enhanced the growth and feed performances, intestinal histomorphological features, growth-related genes, and immune response.

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Section: Discussionmentioning

confidence: 99%

Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Magouz

Radwan²,

Soltan

et al. 2023

Annals of Animal Science

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“…Embora a maior parte do hormônio do crescimento seja produzida pela glândula pituitária, diversos outros tecidos apresentam uma produção discreta do hormônio. Além da função autócrina, o hormônio do crescimento também desempenha função parácrina, ou seja, participação de comunicação célula-célula 4 .…”

Section: Somatropinaunclassified

Uso do hormônio do crescimento associado à fibrina rica em plaquetas e leucócitos injetável (I-PRF)

Silva

Giacomin

Warmeling

et al. 2019

Rev. da Fac. de Odontologia, UPF

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Objetivo: demonstrar, por meio de uma revisão de literatura, a utilização do hormônio do crescimento (GH) e concentrados plaquetários e sugerir técnica de associação de uso para odontologia em processos de preservação de osso alveolar. Revisão de literatura: enxertos ósseos são uma necessidade na área da saúde, por diversas razões. A utilização de osso autógeno apresenta grande desvantagem em ter um segundo sítio cirúrgico, entretanto, os substitutos ósseos não possuem as características ideais. Assim, existe a busca por alternativas que otimizem a cicatrização e a incorporação dos substitutos ósseos, dentre elas os concentrados sanguíneos, ricos em fatores de crescimento derivados das plaquetas e o hormônio do crescimento. É possível encontrar uma vasta literatura utilizando os concentrados sanguíneos, inclusive utilizando esses como veículos para outras substâncias. Os concentrados sanguíneos são ricos em fatores de crescimento derivados das plaquetas, como fator de crescimento semelhante à insulina (IGF), Fator de crescimento derivado de plaquetas (PDGF) e outros. Além disso, também é possível encontrar, na literatura, o uso tópico de hormônio do crescimento em enxertos ósseos, fraturas e implantes dentários. Entretanto, o GH possui uma meia-vida de 20 minutos, assim, quando utilizado em conjunto com a I-PRF, espera-se um aumento no tempo de ação local. Considerações finais: é possível otimizar os enxertos ósseos utilizando-se L-PRF/I-PRF e hormônio do crescimento. Porém, são necessárias mais pesquisas.

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“…On the other hand, it is known that GH has a paracrine effect on bone, besides the well-known endocrine action (21). However, only a few papers have evaluated whether IGF-I could have a local effect on bone.…”

Section: Introductionmentioning

confidence: 99%

Effects of locally applied Insulin-like Growth Factor-I on osseointegration

López-Quiles¹,

Forteza-López²,

Montiel³

et al. 2019

Med Oral

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Background: The aim of this study was to assess the effect of local application of IGF-I on osseointegration of dental implants placed in osteoporotic bones. Material and Methods: 16 rabbits were randomly distributed into two groups: eight animals were ovariectomized and fed a low-calcium diet for six weeks, in order to induce experimental osteoporosis, and the others were shamoperated and fed a standard diet. A titanium implant was inserted into the tibiae in both groups. In half of the rabbits, 4 μg of IGF-I was applied into the ostectomy, prior to the implant insertion. A total of 32 implants were placed. Animals were sacrificed two weeks after surgery and decalcified samples were processed for Bone-To-Implant Contact (BIC) and Bone Area Density (BAD) measurements. Analysis of variance (ANOVA) was used for statistical evaluation. P<0.05 was considered to be significant. Results: Ovariectomy induced statistically significant lower BAD values (p=0.008) and a tendency towards lower BIC values when compared osteoporotic and healthy groups. The administration of 4 μg of IGF-I did not produce statistically significant differences neither on BIC nor on BAD values, neither in the osteoporotic animals nor in healthy.

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Growth hormone

Cited by 76 publications

References 202 publications

Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Uso do hormônio do crescimento associado à fibrina rica em plaquetas e leucócitos injetável (I-PRF)

Effects of locally applied Insulin-like Growth Factor-I on osseointegration

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Growth hormone

Cited by 76 publications

References 202 publications

Synbiotic Lactic Dry® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Synbiotic Lactic Dry® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Uso do hormônio do crescimento associado à fibrina rica em plaquetas e leucócitos injetável (I-PRF)

Effects of locally applied Insulin-like Growth Factor-I on osseointegration

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Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater

Synbiotic Lactic Dry^® enhanced the growth performance, growth-related genes, intestinal health, and immunity of Nile tilapia reared in inland brackish groundwater