Growth differentiation factor 15 in pregnant women: A hero or villain?

Li, Yiu‐Tai; Chao, Wei‐Ting; Wang, Peng-Hui

doi:10.1016/j.tjog.2021.05.003

Cited by 6 publications

(6 citation statements)

References 16 publications

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“…The change should make a real difference to subject lives, how long the effect remains, consumer acceptability, costeffectiveness, and ease of implementation. [12][13][14][15] Sung et al's 4 study seemed to have the aforementioned misinterpretation.…”

Section: Yeh Et Almentioning

confidence: 97%

“…4 NICU administration rate seemed to be different between two groups, although statistically significant difference was also absent. 4 As emphasized by us before, 12–15 the statistical significance is only a really reflective of the findings of the study based on the reliability of the study results, but it may not be totally presentative of “the extent of change.” The change should make a real difference to subject lives, how long the effect remains, consumer acceptability, cost-effectiveness, and ease of implementation. 12–15 Sung et al’s 4 study seemed to have the aforementioned misinterpretation.…”

mentioning

confidence: 96%

“…4 As emphasized by us before, 12–15 the statistical significance is only a really reflective of the findings of the study based on the reliability of the study results, but it may not be totally presentative of “the extent of change.” The change should make a real difference to subject lives, how long the effect remains, consumer acceptability, cost-effectiveness, and ease of implementation. 12–15 Sung et al’s 4 study seemed to have the aforementioned misinterpretation.…”

mentioning

confidence: 96%

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Selective feticide in late trimester: Misinterpretation

Yeh

Horng

Wang

2022

Journal of the Chinese Medical Association

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Section: Yeh Et Almentioning

confidence: 97%

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confidence: 96%

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confidence: 96%

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Selective feticide in late trimester: Misinterpretation

Yeh

Horng

Wang

2022

Journal of the Chinese Medical Association

Self Cite

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“…The change should make a real difference to subject lives, how long the effect remain, consumer acceptability, costeffectiveness, and ease of implementation. [61][62][63] In fact, many clinical and pathological parameters were associated with worse prognosis of UCS. Some of them may be a bias inducing unpredicted results.…”

Section: Clinical-pathological Prognostic Factorsmentioning

confidence: 99%

Comparing paclitaxel-platinum with ifosfamide-platinum as the front-line chemotherapy for patients with advanced-stage uterine carcinosarcoma

Huang

et al. 2022

Journal of the Chinese Medical Association

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Malignant mixed Müllerian tumors (MMMT, carcinosarcomas [CS]) of female genital tract are defined histologically as a biphasic tumor consisting of both carcinoma (malignant epithelial elements) and sarcoma (malignant mesenchymal or stromal elements) components. 1-3 CS usually arises from the uterus but may also rarely appear in the ovary, Fallopian tube, cervix, or peritoneum. [4][5][6] In the past and traditionally, uterine CS (UCS) has been regarded as a subtype of uterine sarcomas and is often analyzed after grouping other uterine sarcomas, such as undifferentiated uterine sarcoma, endometrial stromal sarcoma, and leiomyosarcoma. [7][8][9][10] Recently, clinical, pathologic, and biological evidence has indicated that UCS is a monoclonal origin, which is derived from the Müllerian duct and closely related to high-grade endometrial carcinoma with the driving force to result in sarcomatous transformation (metaplastic carcinoma), and subsequently form the homologous or heterologous groups, depending on the characteristics of the stroma or mesenchymal components of endometrial tissues. [11][12][13] Primary complete surgical staging or primary cytoreductive surgery (PCS) is a key factor in the management of women with UCS, based on the studies obtained from the experience for high-grade or advanced endometrial cancer and uterine sarcomas as well as epithelial ovarian cancer, primary peritoneal serous carcinoma, and primary fallopian tube cancers. 10,14-21 PCS includes a total hysterectomy, bilateral salpingo-oophorectomy,

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“…Since DM is a chronic systemic inflammatory disease and shares the similar pathophysiological disorders of many other chronic diseases or aging process, such as cancers, hereditary diseases, and many others, 4,7,8,10,[12][13][14][15][48][49][50][51] DM is associated with many morbidities. Morbidity from DM is mainly secondary to microvascular damage and dysfunction (hypertension, retinopathy, nephropathy, neuropathy, diabetic foot, and nonalcoholic fatty liver), macrovascular injury and occlusion (hypertension, atherosclerotic cardiovascular disease), and acute complications of life-threatening diseases, including hyperglycemia (hyperglycemia hyperosmolar nonketotic coma and diabetic ketoacidosis) or hypoglycemia.…”

Section: Type 2 Diabetes Mellitus and Morbidities Or Concomitant Como...mentioning

confidence: 99%

To do one and to get more: Part I. Diabetes and bone

Lee

Wang

Yang

et al. 2022

Journal of the Chinese Medical Association

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Type 2 diabetes mellitus (T2DM), is a chronic metabolic disease, characterized by the presence of hyperglycemia and insulin resistance. The key treatment strategies for T2DM include modification of lifestyle, medications, and continuous glucose monitoring. DM patients often have DM-associated morbidities and comorbidities; however, disorders of musculoskeletal system are often neglected, compared to other major systems in DM patients. Based on sharing similar pathophysiology of DM and osteoporosis, it is supposed that the use of antidiabetic agents (ADAs) may not only provide the lowering glucose level effect and the maintenance of the sugar homeostasis to directly delay the tissue damage secondary to hyperglycemia but also offer the benefits, such as the prevention of developing osteoporosis and fractures. Based on the current review, evidence shows the positive correlation between DM and osteoporosis or fracture, but the effectiveness of using ADA in the prevention of osteoporosis and subsequent reduction of fracture seems to be inconclusive. Although the benefits of ADA on bone health are uncertain, the potential value of "To do one and to get more" therapeutic strategy should be always persuaded. At least, one of the key treatment strategies as an establishment of healthy lifestyle may work, because it improves the status of insulin resistance and subsequently helps DM control, prevents the DM-related micro-and macrovascular injury, and possibly strengthens the general performance of musculoskeletal system. With stronger musculoskeletal system support, the risk of "fall" may be decreased, because it is associated with fracture. Although the ADA available in the market does not satisfy the policy of "To do one and to get more" yet, we are looking forward to seeing the continuously advanced technology of drug development on diabetic control, and hope to see their extra-sugar-lowering effects.

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Growth differentiation factor 15 in pregnant women: A hero or villain?

Cited by 6 publications

References 16 publications

Selective feticide in late trimester: Misinterpretation

Selective feticide in late trimester: Misinterpretation

Comparing paclitaxel-platinum with ifosfamide-platinum as the front-line chemotherapy for patients with advanced-stage uterine carcinosarcoma

To do one and to get more: Part I. Diabetes and bone

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