Growing Teratoma Syndrome a Rare Clinical Entity: Two Decades Management Experience from the Regional Cancer Institute

Rathod, Praveen S.; Singh, Amarinder; R, Punyashree; Pallavi, V. R.; Adiga, Usha; Vijay, C R; Shoba, K.; Rajshekar, K

doi:10.1007/s13193-020-01224-1

Cited by 3 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For patients with completely resected disease recurrences can occur, but these are usually within the first 2 years after surgery. 3 12 When recurrences are found after previously negative imaging, it is important to get histologic documentation of mature teratoma as if immature or mixed elements are present, then the patients will often require chemotherapy in addition to surgery. Our patient has now undergone her first surveillance imaging which showed no evidence of disease.…”

Section: Case Presentationmentioning

confidence: 99%

Growing teratoma syndrome

Nitecki

Hameed

Bhosale

et al. 2023

Int J Gynecol Cancer

View full text Add to dashboard Cite

Section: Case Presentationmentioning

confidence: 99%

Growing teratoma syndrome

Nitecki

Hameed

Bhosale

et al. 2023

Int J Gynecol Cancer

View full text Add to dashboard Cite

“…Other suggest that treatment of the malignant components of germ cell tumors "enable" the uninhibited growth of the mature teratoma component [31]. Treatment consists of radical surgery, for which the prognosis is good [34]. We had two cases of germ cell tumors, both of which were submitted to total resection and had a good outcome.…”

Section: Germ Cell Tumorsmentioning

confidence: 99%

Prognostic factors of pediatric pineal region tumors at a single institution

et al. 2023

View full text Add to dashboard Cite

Purpose: To identify factors of a worse prognosis among different histological types of pineal region tumors in pediatric patients treat at a single institution in a 30-year period.Material and Methods: 151 pediatric patients (< 18 years of age) treated between 1991 and 2020 were analyzed. Kaplan-Meyer survival curves were created and the log-rank test was used to compare the main prognostic factors in the different histological types.Results: Germinoma was found in 33.1%, with an overall 60-month survival rate of 88%; the female sex was the only factor of a worse prognosis. Non-germinomatous germ cell tumors were found in 27.1%, with an overall 60-month survival rate of 67.2%; metastasis upon diagnosis, residual tumor and the absence of radiotherapy were associated with a worse diagnosis. Pineoblastoma was found in 22.5%, with an overall 60-month survival rate of 40.7%; the male sex was the only factor of a worse prognosis; a tendency toward a worse outcome was found in patients < 3 years of age and those with metastasis upon diagnosis. Glioma was identi ed in 12.5%, with an overall 60-month survival rate of 72.6%; high grade gliomas were associated with a worse prognosis. Atypical teratoid rhabdoid tumors was found in 3.3% and all patients died within a 19-month period.Conclusion: Pineal region tumors are characterized by the heterogeneity of histological types, which exert an in uence on the outcome. Knowledge of the prognostic factors for each histological types is of extreme importance to the determination of guided multidisciplinary treatment.

show abstract

Prognostic factors of pediatric pineal region tumors at a single institution

Valsechi

Costa

Dastoli

et al. 2022

Preprint

View full text Add to dashboard Cite

Purpose: To identify factors of a worse prognosis among different histological types of pineal region tumors in pediatric patients treat at a single institution in a 30-year period. Material and Methods: 151 pediatric patients (< 18 years of age) treated between 1991 and 2020 were analyzed. Kaplan-Meyer survival curves were created and the log-rank test was used to compare the main prognostic factors in the different histological types. Results: Germinoma was found in 33.1%, with an overall 60-month survival rate of 88%; the female sex was the only factor of a worse prognosis. Non-germinomatous germ cell tumors were found in 27.1%, with an overall 60-month survival rate of 67.2%; metastasis upon diagnosis, residual tumor and the absence of radiotherapy were associated with a worse diagnosis. Pineoblastoma was found in 22.5%, with an overall 60-month survival rate of 40.7%; the male sex was the only factor of a worse prognosis; a tendency toward a worse outcome was found in patients < 3 years of age and those with metastasis upon diagnosis. Glioma was identified in 12.5%, with an overall 60-month survival rate of 72.6%; high grade gliomas were associated with a worse prognosis. Atypical teratoid rhabdoid tumors was found in 3.3% and all patients died within a 19-month period. Conclusion: Pineal region tumors are characterized by the heterogeneity of histological types, which exert an influence on the outcome. Knowledge of the prognostic factors for each histological types is of extreme importance to the determination of guided multidisciplinary treatment.

show abstract

Growing Teratoma Syndrome a Rare Clinical Entity: Two Decades Management Experience from the Regional Cancer Institute

Cited by 3 publications

References 22 publications

Growing teratoma syndrome

Growing teratoma syndrome

Prognostic factors of pediatric pineal region tumors at a single institution

Prognostic factors of pediatric pineal region tumors at a single institution

Contact Info

Product

Resources

About