Greffe de tissu adipeux autologue dans la prise en charge chirurgicale des cicatrices douloureuses : résultats préliminaires

The Use of Autologous Fat Grafting for Treatment of Scar Tissue and Scar-Related Conditions

“…Autologous fat grafting is used as treatment for a variety of symptoms related to scar tissue, including the appearance of the scar and skin characteristics (Table 2), [22][23][24][25][26][27] restoration of volume and/or (three-dimensional) contour (Table 3), 25,28-39 pain (Table 4), 26,27,[40][41][42][43][44] and itch (Table 5). 26,27,43 Autologous fat grafting is also used in combination with other treatments (Table 6).…”

“…39,[45][46][47] The levels of evidence were II in five studies, 33,36,39,41,45 III in seven studies, [23][24][25][26]38,42,44 and IV in 14 studies. 22,23,[28][29][30]32,34,35,37,40,43,[46][47][48] Four randomized controlled trials, 33,36,39,45 16 prospective cohort studies, 22,[25][26][27]29,30,32,34,35,37,38,[41][42][43][44]46 and six retrospective cohort studies …”

“…Seven studies showed a statistically significant res ult, [25][26][27]33,41,42,44 and 19 studies did not report any statistical analyses. [22][23][24][28][29][30][31][32][34][35][36][37][38][39][40]43,[45][46][47] …”

“…[23][24][25][26][27]29,30,32,35,37,[40][41][42][44][45][46][47] Although more procedures maintain the histologic structure, Pu et al 57 described that the Coleman technique creates a higher percentage of viable adipocytes and sustains a more optimal level of cellular function within the harvested fat grafts. Gentile et al 25 described the use of stromal vascular cell fractionenhanced autologous fat grafting according to the Coleman technique.…”

“…26,27,[40][41][42][43][44] After a follow-up of 6 to 13 months, there was a significant reduction of pain in 133 patients treated with autologous fat grafting for postmastectomy pain syndrome, 41,42 in 20 patients with painful and retractile scars located throughout the body, 26 and in 20 patients with pain after episiotomy and perineal laceration. 44 Baptista et al 40 described a complete disappearance of pain in three patients, and six patients reported a decrease in pain. Eight patients reported a reduction in use of pain medications, with a followup of 14 months after treatment with autologous fat grafting according to the Coleman technique.…”