“…ZnO, AgNPs, TiO 2 , Fe 3 O 4 ) have been manufactured and incorporated into different products (e.g., plastics, glass, textiles, reinforce, pigments, medical devices and many others) to expand their properties and broaden product's applications 5,6 . It was possible thanks to the unique capabilities of metal oxides, such as catalytic, antimicrobial, antioxidant, optoelectronic or ferromagnetic characteristics 5, 6 . It was also found that some of those attractive metal oxides can be cyto-and/or genotoxic and induce cellular changes resulting in a disruption of mitochondrial membrane integrity, DNA fragmentation and cell death.…”