Green Synthesis of Silver Nanoparticles Using Leaves Extract of Bauhinia Tomentosa Linn and its Invitro Anticancer Potential

Mukundan, D.; Ramasamy, Mohankumar; Vasanthakumari, R.

doi:10.1016/j.matpr.2015.10.014

Cited by 35 publications

(18 citation statements)

References 10 publications

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“…2a). Similar behavior of AuNPs has been reported by Mukundan et al [21]. The stability of the biogenic AuNPs was monitored under UV-visible spectroscopy at different time durations (6 h-2 mo).…”

Section: Uv-visible Spectroscopy and Stabilitysupporting

confidence: 77%

In Vitro Cytotoxicity and Antioxidant Evaluation of Biogenic Synthesized Gold Nanoparticles From Marsilea Quadrifolia on Lung and Ovarian Cancer Cells

Balashanmugam

Christas²,

Kowsalya³

2018

Int J App Pharm

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Objective: The biogenic gold nanoparticles are considered to be extremely impressive for its wide range of applications in pharmaceutics and therapeutics. The present study was aimed at the biogenic synthesis of gold nanoparticles (AuNPs) from Marsilea quadrifolia aqueous extract and to investigate its antioxidant property and cytotoxic effect on human ovarian teratocarcinoma (PA-1) and lung adenocarcinoma (A549) cell lines.Methods: The biogenic AuNPs was synthesized using an aqueous extract of Marsilea quadrifolia. The synthesized biogenic AuNPs were characterized by ultraviolet (UV) visible spectroscopy, transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX) and X-ray diffraction (XRD). The biogenic AuNPs was assessed for its stability over a period of time and antioxidant activity. The cytotoxicity of biogenic AuNPs against PA-1 and A549 cell lines was studied using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.Results: The synthesized biogenic AuNPs showed peculiar ruby red color and a surface plasmon resonance (SPR) peak at 544 nm in the UV-Vis spectrum. The characterization of biogenic AuNPs by TEM, EDX and XRD revealed well dispersed spherical particles ranging from 10-40 nm and the presence of elemental gold and its crystalline nature, respectively. The AuNPs showed good stability and the scavenging activity at 50 μg/ml. The in vitro cytotoxicity of biogenic AuNPs against PA-1 and A549 cell lines recorded half maximal inhibitory concentration (IC50) of 45.88 μg/ml and 52.015 μg/ml, respectively.Conclusion: The biogenic AuNPs demonstrated superior antioxidant and antiproliferative activities against cancer cell lines.

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Section: Uv-visible Spectroscopy and Stabilitysupporting

confidence: 77%

In Vitro Cytotoxicity and Antioxidant Evaluation of Biogenic Synthesized Gold Nanoparticles From Marsilea Quadrifolia on Lung and Ovarian Cancer Cells

Balashanmugam

Christas²,

Kowsalya³

2018

Int J App Pharm

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“… Diospyros ferrea Ebenaceae Diospyros UV-VIS spectroscopy, FT-IR, SEM 70 – 90 – [45] 30. Bauhinia tomentosa Fabaceae Yellow bauhinia UV-Visible Spectrophotometer, FTIR, FESEM, EDAX, HR-TEM, XRD 31.32 Crystalline [46] 31. Bougainvillea glabra Nyctaginaceae Paper flower UV-visible spectral, FTIR, – – [47] 32.…”

Section: Different Parts Of Plantmentioning

confidence: 99%

Phyto-assisted synthesis, characterization and applications of gold nanoparticles – A review

Santhoshkumar

Rajeshkumar

Kumar

2017

Biochemistry and Biophysics Reports

145

116

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Nanotechnology is the formation, running and use of operation at the nanomaterial size scale (1–100 nm). Nanoscale materials can also be obtained by biological synthesis materials via eco-friendly green chemistry based technique. Current development and numerous strategies involved in the green synthesis of nanoparticles were focussed. This review mainly focused on plants which include scientific name, family name, common name, plant parts, its characterization, size and shape of the nanoparticles. Plant extract which was done experimentally gives its various characterization which leads to the identification of compounds of different nano size and shape. Biosynthesis of gold nanoparticles is in different shapes like spherical, rod, cubic, triangle and also in different sizes. Various application and importance of gold nanoparticles in numerous fields were discussed. The mark of the review is to provide an overview of recent learning in biosynthesized nanoparticles, its characterization and their potential applications.

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“…1b) showed four major peaks at 2θ = 37.97°, 44.12°, 64.34°, and 77.39° corresponding to the indices of (111), (200), (220) and (311) are in good agreement with (JCPDS 04-0783) which confirmed that the hydrothermally synthesized Ag NPs are nanocrystalline with the fcc crystal structure. However, secondary small intensity peaks seen in the PXRD patterns may be due to biomolecules of the Azadirachta indica A. Juss leaf extract that were binding to NPs surface [35]. The average crystallite sizes of the obtained Ag NPs were calculated by using the Debye-Scherrer formula (Eq.…”

Section: Powder X-ray Diffraction (Pxrd)mentioning

confidence: 99%

Environmental and antimicrobial properties of silver nanoparticles synthesized using Azadirachta indica Juss leaves extract

Ramar¹,

Gnanamoorthy

Mukundan

et al. 2018

SN Appl. Sci.

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This study employs a green, eco-friendly and convenient hydrothermal method for the synthesis of stable silver nanoparticles (Ag NPs) using medically beneficial Azadirachta indica A. Juss leaf extract as reducing as well as capping agent. Careful optimization of hydrothermal conditions leads to the formation of spherical Ag NPs of size 9-15 nm. Thus, synthesized NPs are characterized by spectroscopy and microscopy techniques, revealing the morphology and size the NPs. The chemical composition and functionality of the plant extract and NPs is studied using FTIR and EDS analysis. The photocatalytic activity of Ag NPs is demonstrated by decolourization of Rose Bengal under visible light. Ag NPs also show bactericidal activity against E. coli, K. pneumonia, S. epidermidis and S. pneumoniae.

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Green Synthesis of Silver Nanoparticles Using Leaves Extract of Bauhinia Tomentosa Linn and its Invitro Anticancer Potential

Cited by 35 publications

References 10 publications

In Vitro Cytotoxicity and Antioxidant Evaluation of Biogenic Synthesized Gold Nanoparticles From Marsilea Quadrifolia on Lung and Ovarian Cancer Cells

In Vitro Cytotoxicity and Antioxidant Evaluation of Biogenic Synthesized Gold Nanoparticles From Marsilea Quadrifolia on Lung and Ovarian Cancer Cells

Phyto-assisted synthesis, characterization and applications of gold nanoparticles – A review

Environmental and antimicrobial properties of silver nanoparticles synthesized using Azadirachta indica Juss leaves extract

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