Green Synthesis of Silver Nanoparticles Combined to Calcium Glycerophosphate: Antimicrobial and Antibiofilm Activities

Souza, José Antônio Santos; Barbosa, Débora Barros; Berretta, Andresa Aparecida; Amaral, Jackeline Gallo do; Gorup, Luiz Fernando; Neto, Francisco Nunes de Souza; Fernandes, Rosa Áurea Quintella; Fernandes, Gabriela Leal Peres; Camargo, Emerson R.; Agostinho, Alessandra Marçal; Delbem, Alberto Carlos Botazzo

doi:10.2217/fmb-2017-0173

Cited by 24 publications

(17 citation statements)

References 68 publications

(66 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plant extracts are the most advantageous biological materials since they are free from toxic chemicals, present lower biohazards, and provide natural capping agents for AgNPs stabilization. The synthesis of compound G was performed with polyphenols-rich pomegranate peel extract [13], which is responsible for Ag ? ion reduction and AgNPs stabilization, and has excellent anti-oxidant properties [21].…”

Section: Discussionmentioning

confidence: 99%

“…The reaction occurred under constant agitation at 95°C for 10 min. For both routes, the amount of silver was equivalent to 10% of the CaGP weight [12,13].…”

Section: Synthesis Of Test Solutionsmentioning

confidence: 99%

“…These nanocompounds were previously characterized using the UV-visible spectrum, X-ray diffraction, and scanning electron microscopy followed by energy-dispersive X-ray spectroscopy with mapping in 2D, as described by Fernandes et al [12] and Souza et al [13].…”

Section: Synthesis Of Test Solutionsmentioning

confidence: 99%

“…Calcium glycerophosphate (CaGP) is an organic polyphosphate capable of adsorption to enamel surfaces [11], leading to the release of calcium (Ca) ions, which act on the remineralization process. Nanocomposites containing AgNPs and CaGP have been developed and demonstrated antimicrobial and remineralizing effects, attributed to the AgNPs and CaGP, respectively [12,13]. However, there is concern regarding the use of AgNPs, since a concentration-dependent toxicity has been documented [14].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Antimicrobial Activity of Compounds Containing Silver Nanoparticles and Calcium Glycerophosphate in Combination with Tyrosol

et al. 2019

View full text Add to dashboard Cite

Nanocomposites containing antimicrobial agents and calcium phosphates have been developed. Thus, this study assessed the effects of two compounds containing silver nanoparticles (AgNPs) and b-calcium glycerophosphate (CaGP), associated or not with tyrosol (TYR), against planktonic cells and biofilms of Candida albicans and Streptococcus mutans. The nanocompounds were synthesized through chemical and 'green' processes and characterized by scanning electron microscopy. The minimum and fractional inhibitory concentrations of each compound were determined for planktonic cells. Next, 24-h single biofilms of C. albicans and S. mutans were treated for 24 h with the nanocompounds alone or in combination with TYR, and the antibiofilm effect was assessed through enumeration of colony forming units. Biofilm data were statistically examined using one-way ANOVA and the Kruskal-Wallis test (a = 0.05). The chemically synthesized nanocompound in combination with TYR demonstrated a synergistic effect against planktonic cells of C. albicans and S. mutans. For the nanocompound obtained through the 'green' route associated with TYR, a synergistic effect was observed only against C. albicans. For biofilms, only the combination obtained through the 'green' route ? TYR demonstrated a synergistic effect against C. albicans. Our results may contribute to the development of oral care products containing AgNPs-CaGP and TYR to combat oral infections.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The reaction occurred under constant agitation at 95°C for 10 min. For both routes, the amount of silver was equivalent to 10% of the CaGP weight [12,13].…”

Section: Synthesis Of Test Solutionsmentioning

confidence: 99%

Section: Synthesis Of Test Solutionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial Activity of Compounds Containing Silver Nanoparticles and Calcium Glycerophosphate in Combination with Tyrosol

et al. 2019

View full text Add to dashboard Cite

show abstract

“…These composites demonstrated significant antimicrobial activity, especially against S. mutans, which might make them a possible alternative for new dental materials [66,67]. Silver nanoparticles, combined with calcium glycerophosphate as well as nanostructured silver vanadate in dental acrylic resins, have also been shown to have antimicrobial and antibiofilm activities against dental prostheses-associated microorganisms [73,74]. Silver has found several uses since its toxicity toward human cells is considerably lower than toward bacteria; thus, this application is promising.…”

Section: Chemical Compounds With Activity Against Streptococcus Mutanmentioning

confidence: 99%

Management of Streptococcus mutans-Candida spp. Oral Biofilms’ Infections: Paving the Way for Effective Clinical Interventions

Salehi

Kręgiel

Mahady

et al. 2020

JCM

View full text Add to dashboard Cite

Oral diseases are considered the most common noncommunicable diseases and are related to serious local and systemic disorders. Oral pathogens can grow and spread in the oral mucosae and frequently in biomaterials (e.g., dentures or prostheses) under polymicrobial biofilms, leading to several disorders such as dental caries and periodontal disease. Biofilms harbor a complex array of interacting microbes, increasingly unapproachable to antimicrobials and with dynamic processes key to disease pathogenicity, which partially explain the gradual loss of response towards conventional therapeutic regimens. New drugs (synthesized and natural) and other therapies that have revealed promising results for the treatment or control of these mixed biofilms are presented and discussed here. A structured search of bibliographic databases was applied to include recent research. There are several promising new approaches in the treatment of Candida spp.–Streptococcus mutans oral mixed biofilms that could be clinically applied in the near future. These findings confirm the importance of developing effective therapies for oral Candida–bacterial infections.

show abstract

Synergy of Biodegradable Polymer Coatings with Quaternary Ammonium Salts Mediating Barrier Function Against Bacterial Contamination and Dehydration of Eggs

Silva

Gorup

Araújo

et al. 2020

Food Bioprocess Technol

View full text Add to dashboard Cite

Green Synthesis of Silver Nanoparticles Combined to Calcium Glycerophosphate: Antimicrobial and Antibiofilm Activities

Abstract: AgNPs associated or not to calcium glycerophosphate produced by a 'green' process may be a promising novel antimicrobial agent against oral microorganisms.

Cited by 24 publications

References 68 publications

Antimicrobial Activity of Compounds Containing Silver Nanoparticles and Calcium Glycerophosphate in Combination with Tyrosol

Antimicrobial Activity of Compounds Containing Silver Nanoparticles and Calcium Glycerophosphate in Combination with Tyrosol

Management of Streptococcus mutans-Candida spp. Oral Biofilms’ Infections: Paving the Way for Effective Clinical Interventions

Synergy of Biodegradable Polymer Coatings with Quaternary Ammonium Salts Mediating Barrier Function Against Bacterial Contamination and Dehydration of Eggs

Contact Info

Product

Resources

About