Green synthesis of RGO-ZnO mediated Ocimum basilicum leaves extract nanocomposite for antioxidant, antibacterial, antidiabetic and photocatalytic activity

Malik, Abdul; Nasir, Sadia; Shaheen, Fozia; Khalid, Muhammad Zubair; Iqbal, Yasir; Faisal, Abrar; Aziz, Muhammad Hammad; Atif, M.; Ahmad, Shafiq; Fakhar-e-Alam, M.; Hossain, Nazia; Ahmad, Hijaz; Botmart, Thongchai

doi:10.1016/j.jscs.2022.101438

Cited by 48 publications

(13 citation statements)

References 61 publications

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“…Reduced graphene oxide-zinc oxide (RGO-ZnO) NPs were prepared using basilicum leaves extract (Raouf Malik et al, 2022). In photocatalytic activity, the ZnO NPs and RGO-ZnO NPs were tested as the catalyst and degraded the RhB dye 91.4% and 96.7% under UV-vis light.…”

Section: Some Case Studies Of Photocatalytic Activity Of Green Synthe...mentioning

confidence: 99%

Photocatalytic Activity Induced by Metal Nanoparticles Synthesized by Sustainable Approaches: A Comprehensive Review

et al. 2022

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Nanotechnology is a fast-expanding area with a wide range of applications in science, engineering, health, pharmacy, and other fields. Among many techniques that are employed toward the production of nanoparticles, synthesis using green technologies is the simplest and environment friendly. Nanoparticles produced from plant extracts have become a very popular subject of study in recent decades due to their diverse advantages such as low-cost synthesis, product stability, and ecofriendly protocols. These merits have prompted the development of nanoparticles from a variety of sources, including bacteria, fungi, algae, proteins, enzymes, etc., allowing for large-scale production with minimal contamination. However, nanoparticles obtained from plant extracts and phytochemicals exhibit greater reduction and stabilization and hence have proven the diversity of properties, like catalyst/photocatalyst, magnetic, antibacterial, cytotoxicity, circulating tumor deoxy ribo nucleic acid (CT-DNA) binding, gas sensing, etc. In the current scenario, nanoparticles can also play a critical role in cleaning wastewater and making it viable for a variety of operations. Nano-sized photocatalysts have a great scope toward the removal of large pollutants like organic dyes, heavy metals, and pesticides in an eco-friendly and sustainable manner from industrial effluents. Thus, in this review article, we discuss the synthesis of several metal nanoparticles using diverse plant extracts, as well as their characterization via techniques like UV–vis (ultraviolet–visible), XRD (X-ray diffraction), SEM (scanning electron microscopy), TEM (transmission electron microscopy), FTIR (Fourier transform infrared spectroscopy), etc., and catalytic activity on various hazardous systems.

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Section: Some Case Studies Of Photocatalytic Activity Of Green Synthe...mentioning

confidence: 99%

Photocatalytic Activity Induced by Metal Nanoparticles Synthesized by Sustainable Approaches: A Comprehensive Review

et al. 2022

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“…Scanning electron microscopy technology confirmed the spherical shape of the particle size of 31 nm. Moreover, RGO-ZnO inhibited α-amylase and α-glucosidase antidiabetic activities in vitro, and RGO-ZnO NCs showed antibacterial ability with increasing concentration against both Gram-positive (Cocci) and Gram-negative ( E. coli ) strains 25 .…”

Section: Introductionmentioning

confidence: 99%

The effect of different aqueous solutions ratios of Ocimum basilicum utilized in AgNPs synthesis on the inhibition of bacterial growth

Qaeed

Hendi

Obaid

et al. 2023

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This study examined the effect of varying concentrations of Ocimum basilicum aqueous extract, which was done via the green synthesis of Silver nanoparticles (AgNPs), on the identification of the most effective concentration for bacteria inhibitory activity. Different concentrations of the aqueous Ocimum basilicum extract (0.25, 0.50, 0.75 and 1.00 mM) were used as reducing and stabilizing agent to synthesize AgNPs by means of the reduction method. The crystal structure and morphology of the NPs were characterized UV–Vis spectra, X-ray diffraction (XRD) and scanning electron microscopy (SEM). The antibacterial efficacy of AgNPs was studied against E. coli ATCC 35218 using well diffusion, MIC, MBC, and time-kill curve. The dark yellow color of the Ocimum basilicum aqueous solution indicates the successful synthesis process of the AgNPs. UV-spectra of the AgNPs display a gradual increase of absorption in sequence with concentration increase of aqueous Ocimum basilicum extract solution from 0.25 to 1.00 mM. This, in turn, led to a shift in the wavelength from 488 to 497 nm, along with a change in the nanoparticle size from 52 to 8 nm. The tests also showed a high activity of the particles against bacteria (E. coli), ranging between 15.6 and 62.5 µg/ml. Based on AgNPs, it was confirmed that an aqueous Ocimum basilicum extract can be used as an effective, reducing and stabilizing agent for the synthesis of different sizes of AgNPs based on the solvent concentration. The AgNPs also proved to be effective in inhibiting and killing bacteria.

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“…Unfortunately, several types of commonly used commercial drugs are expensive products, and their applications can cause notable health sides effects such as diarrhea, severe hypoglycemia, hepatotoxicity, meteorism, and abdomen distention [6,13]. Therefore, several materials of biologically active and multifunctional chemical groups were recommended as potential antidiabetic and antioxidant agents that can exhibit enhanced inhibition properties against essential enzymes and scavenging properties against ROS radicals [6,14]. Recently, metal oxides and their composites attracted wide attention as effective antioxidants and antidiabetic agents.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, metal oxides and their composites attracted wide attention as effective antioxidants and antidiabetic agents. Besides their low production cost and unique physicochemical properties, metal oxide nanoparticles are characterized by significant biological activity, therapeutic and theranostic potentiality, and biocompatibility [14][15][16][17][18]. Zinc oxide is one of the most investigated metal oxides as bioactive material that is characterized by its biocompatibility, nontoxicity, antidiabetic, and antioxidant properties [18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

et al. 2023

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The kaolinite sheets were scrolled by sonication-induced chemical delamination processes into well-developed nanotubes (KNs) which were used as substrates for microwave-based ZnO nanoparticles (ZnO/KNs). The biological activities of synthetic ZnO/KNs structures, in terms of the antioxidant and antidiabetic properties, were assessed in comparative studies with the separated phases of the synthetic ZnO and KNs as well as the commercially used ZnO. The KNs substrate resulted in a notable enhancement in the antioxidant and antidiabetic properties of ZnO, which was assigned positive influence on the surface area, interactive interfaces, charge separation, and agglomeration properties of ZnO in addition to the detectable bioactive properties of the KNs structure. The ZnO/KNs structure achieved remarkable scavenging efficiencies for 1, 1-diphenyl-2-picrylhydrazil (DPPH) (89.8 ± 1.57%), nitric oxide (90.6 ± 1.63%), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) (86.8 ± 1.28%), and superoxide (43.9 ± 1.72%) radicals. Additionally, it shows high inhibition effects on porcine α-amylase (84.3 ± 1.92%), crude α-amylase (70.6 ± 1.37%), pancreatic α-Glucosidase (94.7 ± 1.54%), crude α-Glucosidase (95.4 ± 1.64%), and amyloglucosidase (95.3 ± 1.32%) enzymes. This antidiabetic activity is significantly higher than the activity of miglitol and close to or slightly higher than acarbose, which leads us to recommend the use of ZnO/KNs when considering the cost and side effects of the commercially used drugs.

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Green synthesis of RGO-ZnO mediated Ocimum basilicum leaves extract nanocomposite for antioxidant, antibacterial, antidiabetic and photocatalytic activity

Cited by 48 publications

References 61 publications

Photocatalytic Activity Induced by Metal Nanoparticles Synthesized by Sustainable Approaches: A Comprehensive Review

Photocatalytic Activity Induced by Metal Nanoparticles Synthesized by Sustainable Approaches: A Comprehensive Review

The effect of different aqueous solutions ratios of Ocimum basilicum utilized in AgNPs synthesis on the inhibition of bacterial growth

Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

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