Green Synthesis of Microbial Nanoparticle: Approaches to Application

Purohit, Jyotika; Chattopadhyay, Anirudha; Singh, Nirbhay Kumar

doi:10.1007/978-3-030-16534-5_3

Cited by 33 publications

(7 citation statements)

References 128 publications

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“…Recently, the biosynthesis of Au-NPs has been preferred over the chemical and physical fabrication of NPs because of the ecofriendly and non-toxic nature of the produced NPs, as well as high biocompatibility and sensitivity (Purohit et al, 2019). UV-visible spectroscopy is used to demonstrate the production of metal NPs by evaluating the unique optical properties of the NPs, which are dependent on their size and shape (Paulkumar et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

In vitro assessment of antimicrobial, anti-inflammatory, and schistolarvicidal activity of macroalgae-based gold nanoparticles

Kamal

Abdel-Raouf²,

Sonbol³

et al. 2022

Front. Mar. Sci.

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There is a growing need to improve facile, eco-friendly, and cheap approaches for nanoparticle (NP) synthesis. Green protocols have been investigated for the fabrication of NPs using several natural sources as plants, algae, fungi, and bacteria. Thus, the present study proposed a rapid, convenient, and efficient biosynthesis of gold NPs (Au-NPs) using the ethanolic extracts of three macroalgae, i.e., Cystoseira myrica, C. trinodis, and Caulerpa prolifera. The reduction of Au ions and the fabrication of Au-NPs were validated using ultraviolet-visible (UV–Vis) spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), and zeta potential analysis. The produced Au-NPs were tested for their antibacterial, antifungal, anti-inflammatory, and schistolarvicidal activity. Results revealed the formation of Au-NPs with an average size of 12.6–15.5 nm and different shapes that are mainly spherical with pure crystalline nature. The strong antibacterial activities of C. trinodis– and C. myrica–based Au-NPs against E. coli (inhibition zones of 22 and 19 mm) and against Staphylococcus aureus (inhibition zones of 18 and 20.5 and mm) were recorded, respectively. On the other hand, the high antifungal activity of C. trinodis Au-NPs against Aspergillus niger and Alternaria alternate showed the inhibition zones of 18 and 17 mm, respectively. The high antifungal activity of C. trinodis Au-NPs against Candida albicans (inhibition zone 16 mm) was also recorded. Regarding anti-inflammatory and schistolarvicidal activity, Au-NPs fabricated using C. myrica showed 64.2% of the inhibitory effect on protein denaturation and recorded the highest schistolarvicidal activity against Schistosoma mansoni cercariae that sank and died after 7 min. Overall, these findings proved that macroalgal ethanolic extracts can be effectively used for the biosynthesis of Au-NPs. These Au-NPs offer a significant alternative antimicrobial, anti-inflammatory, and schistolarvicidal agents. for biomedical uses.

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Section: Discussionmentioning

confidence: 99%

In vitro assessment of antimicrobial, anti-inflammatory, and schistolarvicidal activity of macroalgae-based gold nanoparticles

Kamal

Abdel-Raouf²,

Sonbol³

et al. 2022

Front. Mar. Sci.

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“…Green nanotechnology's main aim is to produce nanomaterials without hazardous environmental or health effects. [49][50][51] The different plant parts such as leaves, roots, stems, bark, etc., are used for nanoparticle synthesis. No harmful substance is used in the synthesis process, indicating that it is an eco-friendly and non-toxic method.…”

Section: Biogenic Approach For Nanoparticle Synthesismentioning

confidence: 99%

Biogenic Zinc Oxide Nanoparticles: An Insight into the Advancements in Antimicrobial Resistance

Sharma,

K.,

Kumari

et al. 2024

ECS J. Solid State Sci. Technol.

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Multidrug resistance (MDR) is a significant global challenge requiring strategic solutions to address bacterial infections. Recent advancements in nanotechnology, particularly in the synthesis of zinc oxide nanoparticles (ZnO NPs) using natural agents as stabilizers and reducing agents, have shown promising results in combating MDR. These nanoparticles possess strong antimicrobial properties against different strains of Gram-positive and Gram-negative, making them suitable for various industries, including food, pharmaceuticals, coatings, and medical devices. ZnO-NPs work by generating reactive oxygen species, releasing zinc ions (Zn2+), disrupting the bacterial cell membrane, interfering with metabolic processes and genetic material, and inducing oxidative stress and apoptosis. However, more research is needed to refine synthesis techniques, control size and morphology, and increase antibacterial efficacy. To fully understand their potential, interactions with proteins, DNA, and bacterial cell walls must also be examined. Investigating the synergistic potential of biogenic ZnO NPs with conventional antibacterial treatments could enhance therapeutic effectiveness while minimizing the risk of resistance emergence. Here we provide insight into the advancements in biogenic synthesis of nanoparticles using bio extracts and their applications in antimicrobial resistance as well as various factors affecting the synthesis process and characterization techniques for ZnO NPs. Recent studies on the antimicrobial activity of biogenic ZnO NPs against different pathogens and their mechanisms of action are discussed. Furthermore, potential applications of biogenic ZnO NPs as antimicrobial agents are highlighted

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“…Extracellular synthesis has been adopted widely and has garnered a noticeable interest due to the elimination of downstream steps of processing in the intracellular method for nanoparticles recovery as it eliminates the cell wall breakdown by sonication, and centrifugation followed by some washing stages necessary for the puri cation of nanoparticles. Furthermore, metal resistance genes, enzymes (Virkutyte and Varma 2011), peptides, proteins, organic materials, and reducing cofactors play a key role in green synthesis by acting as reducing agents, thus helping in the synthesis of nanoparticles by functioning as a natural capping agent and preventing the aggregation and imparting additional stability to nanoparticles for a longer period (Purohit et al 2019; Messaoudi and Bendahou 2020; Rana et al 2020). For nanoparticles, stabilization and surface functionalization became greener by using biocompatible stabilizing agents, i.e., microbes, which can produce vast varieties of stable ower-shaped, spherical, and rod-shaped nanoparticles that have potential uses and diverse applications.…”

Section: Green Synthesis Of Nanoparticles By Microorganismsmentioning

confidence: 99%

Nanomaterials for Sustainability: A Review on Green Synthesis of Nanoparticles Using Microorganisms

Jadoun

Chauhan

Zarrintaj

et al. 2021

Preprint

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Nanotechnology has permeated all areas of sciences as one of the most propitious technology with the deployment of nanoparticles in environmental remediation and biomedical fields; their synthesis under greener conditions has been bourgeoned using microorganisms, plants, etc. to decrease the use of toxic chemicals. Synthesis of nanoparticles by exploiting microorganisms has opened up a new prospect at the interface of nanotechnology, chemistry, and biology enabling access via a biocompatible, safe, sustainable, eco-friendly, and reliable route; microorganisms offer crystal growth, stabilization, and prevention of aggregation thus performing a dual role of reducing and capping agent because of the presence of biomolecules such as enzymes, peptides, poly (amino acids), polyhydroxyalkanoate (PHA), and polysaccharides. Herein, the microorganisms-based synthesis of various nanoparticles comprising gold, silver, platinum, palladium, copper, titanium dioxide, zinc oxide, iron oxide, and selenium along with their appliances in waste treatment, biomedicine namely cancer treatment, antibacterial, antimicrobial, antifungal, and antioxidants, are deliberated.

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Green Synthesis of Microbial Nanoparticle: Approaches to Application

Cited by 33 publications

References 128 publications

In vitro assessment of antimicrobial, anti-inflammatory, and schistolarvicidal activity of macroalgae-based gold nanoparticles

In vitro assessment of antimicrobial, anti-inflammatory, and schistolarvicidal activity of macroalgae-based gold nanoparticles

Biogenic Zinc Oxide Nanoparticles: An Insight into the Advancements in Antimicrobial Resistance

Nanomaterials for Sustainability: A Review on Green Synthesis of Nanoparticles Using Microorganisms

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