Green synthesis of fluorescent nitrogen/sulfur-doped carbon dots and investigation of their properties by HPLC coupled with mass spectrometry

Abstract

A green approach to synthesise nitrogen/sulfur co-doped carbon dots has been developed and the product was successfully analysed by HPLC.

Dual functional N- and S-co-doped carbon dots as the sensor for temperature and Fe3+ ions

“…Especially, distinguishing from metal-based quantum dots, C-dots possess high chemical inertness, low toxicity and good biocompatibility, which can be prepared with facile synthesis approaches. At present, a broad series of methods have been developed for their preparation since fluorescent C-dots were named since 2006 by Sun et al [12], such as chemical oxidation method [13], ultrasonic method [14], hydrothermal synthesis [15] [16], solvothermal method [17], microwave method [18] and laser ablation method [19] which can be divided into two classes of methods, "top-down" and "bottom-up" [20]. Among them, thermal treatment synthesis is regarded as a simple, direct and efficient route for synthesis of C-dots with novel properties.…”

Highly luminescent N, S- Co-doped carbon dots and their direct use as mercury(II) sensor

“…The previously reported N, S-doped carbon dots generally use -SH as sulfur source. [30][31][32]36] In this study, we suggest that C=S group involved RA may be more workable than -SH for the functionalization of N, S-co-doped carbon dots. Specifically, NSCDs are synthesized by using citric acid (CA) and RA as precursors through a facile one step microwave-assisted hydrothermal method.…”

“…Therefore, nitrogen and sulfur co-doped CDs have been investigated with some peculiar properties. [30][31][32] Their usage as fluorescent probes for rapid detection, has been highly expected.…”

Editorial - Sensitivity of Analytical and Bioanalytical Techniques

“…Another typical discussion was on the elucidation of the chemical structures of nanoparticles by the state-of-art mass spectrometry techniques [2][3][4]. It was stated that the application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry exhibits lower sensitivity with increasing mass; the sensitivity of the electrospray ionization quadrupole time-offlight tandem mass spectrometry is much improved, but is still limited to capture the larger ions in high mass range.…”

“…This factor is becoming increasingly important in either quantifying ultra-low concentration substances or in elucidating the accurate chemical structures. The need for developing more sensitive techniques and searching for pathways to improve was noted in some of the important discussions.In one particular discussion of Wang [1], it was stated that the conventional high performance liquid chromatography (HPLC) has sensitivity limitation in metabolomics analyses; the dramatic improvement of LC analyses can be achieved by further refining LC to more advanced ultra-performance liquid chromatography (UPLC), which enables columns packed with particles smaller than 2 μm and benefits higher resolution, faster speed and increased sensitivity.Another typical discussion was on the elucidation of the chemical structures of nanoparticles by the state-of-art mass spectrometry techniques [2][3][4]. It was stated that the application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry exhibits lower sensitivity with increasing mass; the sensitivity of the electrospray ionization quadrupole time-offlight tandem mass spectrometry is much improved, but is still limited to capture the larger ions in high mass range.…”