Green synthesis of Cu/zirconium silicate nanocomposite by using Rubia tinctorum leaf extract and its application in the preparation of N‐benzyl‐N‐arylcyanamides

Abstract

A simple and convenient protocol was established for the synthesis of the N‐benzyl‐N‐arylcyanamides through N‐benzylation of a wide variety of arylcyanamides using copper nanoparticles immobilized on natural zirconium silicate as a novel and green heterogeneous catalyst. In this study, we showed a novel, cost efficient, convenient and simple method for green synthesis of Cu/zirconium silicate nanocomposite by using Rubia tinctorum leaf extract as capping and reducing agent. The structure of the novel catalyst was successfully characterized using a number of micro/spectroscopic techniques such as XRD, FESEM, BET, EDS, TEM, FT‐IR and elemental mapping. TEM micrographs of obtaining biocatalyst revealed mostly spherical particles with an average diameter of about 15–25 nm on the surface of natural support. The prepared catalyst was used in the N‐benzylation of a variety of arylcyanamides with benzyl bromide and showed high activity and stability for the efficient synthesis of N‐benzylarylcyanamides in good yields. Remarkably, the catalyst can be easily recovered from the reaction medium and reused up to five runs without losing its catalytic activity.

Biogenic synthesis of copper oxide nanoparticles using leaf extracts of Cissus quadrangularis and Piper betle and its antibacterial effects

“…Medicinal plants have been playing a crucial role in maintaining human health and civilizing the quality of human life for thousands of years. Ayurveda, unani, homeopathy, naturopathy, siddha, and other alternative medicinal systems have been utilizing plants as effective medicines to cure various diseases [12][13][14]. Plants are valuable source of compounds with reductive abilities called antioxidants.…”

<p>Biosynthesis of Copper Oxide Nanoparticles with Potential Biomedical Applications</p>

“…In this matter, green chemistry area focused on optimizing one of these factors via finding green alternatives for them, or using multicomponent as in situ alternatives for these three factors simultaneously. [9][10][11][12][13][14][15] The use of metal nanoparticles has different applications in different industries, but in general, these nanoparticles play a very important role as catalysts for different reactions including Mizoroki-Heck, Sonogashira, A 3 and carbon-coupling reactions. One of the important factors that can increase the efficiency of different industries is the use of nanoparticles, or better to say, different catalysts with multiple functions, as well as low cost along with high life-time and high efficiency.…”

Plant-Extract-Mediated Synthesis of Metal Nanoparticles

“…Veisi et al [137] found that flavonoids, tannins, and phenolic compounds attached to the surface of AgNPs to keep them stable through electronic interactions. e presence of active components with antioxidant properties in plant extracts that reduce copper ions and synchronously maintain the stability of copper nanoparticles was reported by Nasrollahzadeh et al [138].…”