Green Synthesis of Copper‐oxide Nanoparticles and Evaluation of Its Therapeutic Efficacy

Abstract

An eco‐friendly green route for synthesis copper oxide nanoparticles (CuONPs) by Prunella vulgaris flower aqueous extract is reported. The synthesized copper oxide nanoparticles are characterized in terms crystalline nature, morphology, structural, and antibacterial activity with UV‐vis, SEM, DLS, FTIR analysis tools. The synthesized CuONPs are well crystalline in nature with particle shape spherical and average particle size in the range 41–76 nm. The antimicrobial activity of CuONPs, determined by disk diffusion method against S. aureus and K. pneumoniae, demonstrates a significant inhibitory activity against S. aureus followed by K. pneumoniae. In view of the promising activity, CuONPs can be used as an antibacterial agent. The possible mechanisms of antimicrobial activity of CuONPs should be further investigated.