Green synthesis and properties of arginine derived complexes for assorted drug delivery systems: A review

Patel, Dinal; Patel, Mehul; Dholakia, Mansi S.; Suhagia, Bhanubhai N.

doi:10.1016/j.scp.2021.100441

Cited by 6 publications

(4 citation statements)

References 92 publications

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“…35,36 Arginine, also known as L-Arg, is an amino acid that is alkaline in nature and has guanidino, carboxyl and amino groups in its molecular structure. [37][38][39] It is also the only amino acid that contains guanidine groups, and L-Arg functionalized materials show high affinity for phosphopeptides due to the strong interaction between guanidine and phosphate. [40][41][42][43] Herein, we introduced L-Arg into magnetic CS via a facile procedure to develop an efficient enrichment material focusing on phosphopeptide enrichment.…”

Section: Introductionmentioning

confidence: 99%

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Yang,

Zhou,

Zheng

et al. 2024

Anal. Methods

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Section: Introductionmentioning

confidence: 99%

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Yang,

Zhou,

Zheng

et al. 2024

Anal. Methods

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“…The development and application of APG have become one of the hotspots of research, including environmental protection, biological soil remediation, wastewater treatment, medicine, textile, functional materials, and bioengineering (1996‐2020). [ 13‐38 ]…”

Section: Introductionmentioning

confidence: 99%

Novelty of glycoside surfactant derivatives for sustainable development: A new perspective

Balamurugan,

Lakshmanan,

Piramuthu

et al. 2023

Vietnam Journal of Chemistry

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Sustainable growth for better survival on our mother earth has given an impetus to researchers to develop eco‐friendly, green, high‐performance, cost‐effective materials. In this regard, APG and its derivatives are considered to be very promising chemical moieties in the area of surfactants and detergents. It is all because of their special properties viz, their synergism with other co‐surfactant molecules, low irritation, high foaming, and excellent biodegradation aspects. It makes many researchers do some quality work and study to explore their further goodness for better ecology. A broad range of alkyl polyglucoside derivatives can be obtained by nucleophilic substitution. Among the various derivatives of alkyl polyglucoside, the anionic alkyl polyglycoside esters (AGEs) and AGE‐nonionic surfactant mixtures can able to increase wettability, and it may increase mineral content in soils. The phosphate alkyl polyglucosides show good performance in detergency and better wetting properties with good biodegradability. The sulfonated alkyl polyglucosides are a good alternative to nonylphenol ethoxylate and exhibit superior cleaning of edible oil.

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“…16,17 Arginine significantly increases the transdermal absorption rate through the formation of strong intermolecular bonds with counter ions as well as due to its high affinity for free fatty acids in the skin. 18,19 In this study, an ion pair of arginine and glutamic acid was prepared, the structure of RE:pair caused by a salt bridge of a guanidinium group and carboxyl group was analyzed and wound healing efficacy in keratinocytes and collagen synthesis efficacy in fibroblasts were evaluated. Based on the wound healing effect of RE:pair verified at the cellular level, wounds were induced in artificial skin and the healing process was observed.…”

Section: Introductionmentioning

confidence: 99%

“…In particular, arginine not only has high solubility in water, it is also used as a counter ion in ion pairs due to its cationicity resulting from its guanidinium group 16,17 . Arginine significantly increases the transdermal absorption rate through the formation of strong intermolecular bonds with counter ions as well as due to its high affinity for free fatty acids in the skin 18,19 …”

Section: Introductionmentioning

confidence: 99%

Effects of arginine glutamate (RE:pair) on wound healing and skin elasticity improvement after CO₂ laser irradiation

Kwon¹,

Won²,

Seo³

et al. 2022

J of Cosmetic Dermatology

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Background: Glutamic acid is known to be effective for keratinocyte proliferation, but its dermatological application is limited due to its poor solubility in water and various solvents.Aim: Here, the efficacy of the arginine glutamate ion pair (named as RE:pair) for recovering damaged skin and improving skin elasticity was investigated through the analysis of keratinocyte proliferation and collagen synthesis.Methods: Following the structural analysis of RE:pair using spectroscopic methods, a scratch assay, and Pro-Collagen I ELISA, skin tissue changes in wound-induced artificial skin, changes in wound area after laser wound induction, and the sensory evaluation of skin improvement were investigated.Results: As a result of scratch assay, wound recovery of 94.55% ± 9.57% was confirmed at 10 ppm RE:pair treatment. When evaluation of expression efficacy of procollagen type I, it was found that the expression rate was increased by 32.47% ± 5.62% compared with the control group. Further, the upregulation of the proliferation marker Ki-67 and filaggrin expression in the damage-induced artificial skin was verified.Clinically, the improvement was subjectively verified in terms of the reduction of the wound area, the restoration of the barrier, the improvement of skin elasticity, and through the sensory experience of skin improvement. Conclusion:RE:pair shows a greater therapeutic effect than the individual effects of its constituent amino acids and those of the simple mixtures of these compounds. RE:pair exerts its therapeutic action by promoting the proliferation of keratinocytes and enhancing collagen synthesis in fibroblasts. Accordingly, it can be used throughout the cosmetic industry as an effective amino acid wound healing and skin elasticity improving material.

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Green synthesis and properties of arginine derived complexes for assorted drug delivery systems: A review

Cited by 6 publications

References 92 publications

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Novelty of glycoside surfactant derivatives for sustainable development: A new perspective

Effects of arginine glutamate (RE:pair) on wound healing and skin elasticity improvement after CO₂ laser irradiation

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Green synthesis and properties of arginine derived complexes for assorted drug delivery systems: A review

Cited by 6 publications

References 92 publications

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Enrichment of phosphopeptides by arginine-functionalized magnetic chitosan nanoparticles

Novelty of glycoside surfactant derivatives for sustainable development: A new perspective

Effects of arginine glutamate (RE:pair) on wound healing and skin elasticity improvement after CO2 laser irradiation

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Effects of arginine glutamate (RE:pair) on wound healing and skin elasticity improvement after CO₂ laser irradiation