Green Synthesis and Evaluation of Copper Oxide Nanoparticles using Fig Leaves and their Antifungal and Antibacterial Activities

Abstract

In this article, a simple new technique for the green synthesis of copper oxide nanoparticles (CuO NPs) using peroxidases oxidoreductases (POX) enzyme extracted from fig leaves for antifungal and antibacterial activities has been reported. Subsequently, a comprehensive investigation of the structural, optical, and morphological properties of the synthesized CuO NPs was elucidated, using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Electrodiagnostic (EDX), atomic force microscopy (AFM), and transmission electron microscopy (TEM) analysis techniques. Specifically, the resultant nanoparticles are spherical with a diameter ranging from 28–68. CuO NPs were further tested for their antifungal activity against Candida and Aspergillus species, while the antibacterial activity was screened in contradiction of pathogenic bacterial strains namely gram-positive Staphylococcus aureus and gram-negative Asinobacterial species. The present study reveals a convenient use of POX fig leaves extract as fuel, for the well-organized synthesis of CuO NPs via green synthesis technique to acquire considerably active antifungal and antibacterial materials.

The Antibacterial Activity of the Biosynthesized Copper Oxide Nanoparticles by Lantana camara Flowers Extract Against Some Bacterial Isolated from Burns

“…Surface morphology of copper oxide nanoparticles and the average grain size diameter were studied utilizing( AFM), This analysis gave clear results about the characterization of the biosynthesized NPs at the nanoscale, Nanoparticle size distributions, Direct visualization of the nanoparticles in 2D and 3D dimensions images and analysis of the size of nanoparticles as well as the size distributions are directly calculated from AFM images [50] the prepared nanoparticles antimicrobial activity is dependent on how Smaller the size of the nanoparticles which resulted in a higher surface area and that mean the NPs are more reactive, Smaller nanoparticles in size than cell membrane pores make them capable of crossing the cell wall and inhibiting the growth of bacteria [ 51].…”