Green rapid synthesis of Cu2O/Ag heterojunctions exerting synergistic antibiosis

Growth of Cu2O Nanoparticles on Two-Dimensional Zr–Ferrocene–Metal–Organic Framework Nanosheets for Photothermally Enhanced Chemodynamic Antibacterial Therapy

“…Bacterial infection is a severe threat to human health all over the world. , Because of the uncontrolled use of antibiotics for a long time, many bacteria have developed drug resistance, which will seriously threaten human health. , Therefore, there is a pressing need to design and develop new antimicrobial platforms to meet the needs of human beings. , In recent years, some antibacterial therapies without using antibiotics have been developed such as the controlled release of silver ions, , photothermal therapy (PTT), , chemodynamic therapy (CDT), − and photodynamic therapy (PDT). , Among them, CDT is a treatment that requires no extra energy input, and thus, it can avoid the limitation of light penetration in tissues . In the last decade, many inorganic nanomaterials, such as metal oxides ,, and metal chalcogenides, − have been developed as nanoagents for antibacterial through CDT because they can catalyze the Fenton or Fenton-like reaction with hydrogen peroxide to generate highly toxic hydroxyl radicals (·OH) to destroy biomolecules (such as DNA and proteins) in bacteria.…”

“…3,4 Therefore, there is a pressing need to design and develop new antimicrobial platforms to meet the needs of human beings. 5,6 In recent years, some antibacterial therapies without using antibiotics have been developed such as the controlled release of silver ions, 7,8 photothermal therapy (PTT), 9,10 chemodynamic therapy (CDT), 11−15 and photodynamic therapy (PDT). 16,17 Among them, CDT is a treatment that requires no extra energy input, and thus, it can avoid the limitation of light penetration in tissues.…”

Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists

“…The antiproliferative activity of compounds 5 – 26 was assessed using the CCK-8 assay ( Chen et al, 2016 ; Chen et al, 2017 ; Chen et al, 2018 ; Han et al, 2020 ; Guo et al, 2021 ; Hu et al, 2022 ; Zhou et al, 2022 ). The 96-well plates (1×10 5 cells/mL) were seeded with cells in a medium, the plates were cultured at 37 °C for 24 h, then different concentrations of tested drugs were added, and the plates were cultured for 24 h. After 24 h, 10 μL of CCK-8 solution (5 mg/ml) was added to the wells, and the cells were cultured for 1 h at 37°C.…”

Rational Design and Synthesis of Ag−Cu2O Nanocomposites for SERS Detection, Catalysis, and Antibacterial Applications

“…A study by Hu et al. suggests that the shape of the hybrid can also affect its antibacterial activity [54] . They noted that the sharp edges in their Cu 2 O@Ag hybrids can puncture the bacterial cell wall, causing the bacteria to burst and die.…”

“…A study by Hu et al suggests that the shape of the hybrid can also affect its antibacterial activity. [54] They noted that the sharp edges in their Cu 2 O@Ag hybrids can puncture the bacterial cell wall, causing the bacteria to burst and die. Meanwhile, there have been interesting studies showing that functionalization with Cu 2 O@Ag can endow materials with antibacterial properties.…”