Abstract:Objectives: A series of new dihydropyrano [2,3-c]pyrazol-6-amines in this investigation study, are synthesized by the strategy of one-pot four component reaction in an aqueous medium.
Methods: After getting optimum conditions the reaction of different substituted aromatic aldehydes, ethyl acetoacetate, hydrazine hydrate, and phenylacetonitrile catalysed by Sodium hydrogen sulphate NaHSO4 (0.5 m mol) by refluxing in ethanol-water (1:1) (5 ml) and heated at 80 oC. The synthesized molecules product was… Show more
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