Green Chemistry and the Health Implications of Nanoparticles

Albrecht, Matthew A.; Evans, Cameron W.; Raston, Colin L.

doi:10.1002/chin.200637267

Cited by 86 publications

(95 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…reduction in solutions, chemical and photochemical reactions in reverse micelles, thermal decomposition of silver compounds, radiation assisted, electro chemical, sono-chemical, microwave-assisted process, and most recently using green chemistry technology (Song and Kim, 2009). The green synthesis approach provides most advantages over the chemical and physical method as it is cost effective, eco- friendly and easy to scaled up for large-scale synthesis without applying energy, high pressure, temperature and toxic chemicals (Albrecht et al, 2006). …”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of Silver Nanoparticles from Protium serratum and Investigation of their Potential Impacts on Food Safety and Control

et al. 2017

View full text Add to dashboard Cite

Silver nanoparticles play an integral part in the evolution of new antimicrobials against the broad ranges of pathogenic microorganisms. Recently, biological synthesis of metal nanoparticles using plant extracts has been successfully consummated. In the present study, the biosynthesis of silver nanoparticles (AgNPs) was conducted using the leaf extract of plant Protium serratum, having novel ethnomedicinal. The synthesized AgNPs were characterized using UV-Visible spectroscopy, dynamic light scattering spectroscopy (DLS), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy. The DLS study revealed the surface charge of the resulted nanoparticles that was highly negative, i.e., −25.0 ± 7.84 mV and the size was 74.56 ± 0.46 nm. The phytochemical and FTIR analysis confirmed the role of water-soluble phyto-compounds for the reduction of silver ions to silver nanoparticles. The potential antibacterial activity of AgNPs was studied against the food borne pathogens viz. Pseudomonas aeruginosa (IC50 = 74.26 ± 0.14 μg/ml), Escherichia coli (IC50 = 84.28 ± 0.36 μg/ml), Bacillus subtilis (IC50 = 94.43 ± 0.4236 μg/ml). The in vitro antioxidant potential of AgNPs was evaluated using 1, 1-diphenyl-2-picryl-hydrazil (IC50 = 6.78 ± 0.15 μg/ml) and hydroxyl radical assay (IC50 = 89.58 ± 1.15 μg/ml). In addition, the cytotoxicity of AgNPs was performed against fibroblast cell line L-929 to evaluate their biocompatibility. The overall results of the present investigation displayed the potential use of P. serratum leaf extract as a good bio-resource for the biosynthesis of AgNPs and their implementation in diverse applications, specifically as antibacterial agent in food packaging and preservation to combat against various food borne pathogenic bacteria along with its pharmaceutical and biomedical applications.

show abstract

Section: Introductionmentioning

confidence: 99%

Biosynthesis of Silver Nanoparticles from Protium serratum and Investigation of their Potential Impacts on Food Safety and Control

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Along with the development of nanotechnology, it is possible to produce medicine in a variety of sizes. Nanotechnology is the application of technology in the field of science and technology to create new materials, including nanoparticles (10 -9 m)(7). …”

Section: Introductionmentioning

confidence: 99%

Biochemical and histopathological effects of green tea nanoparticles in ironized mouse model

2017

View full text Add to dashboard Cite

Transfusion in the treatment of thalassemia gives rise to iron deposits in many organs. Since there are many obstacles in the use of deferoxamin (DFO) as an iron chelating agent, it is important to find another alternative therapy that can act as iron chelation. The study aims to compare the histopathological pictures of the heart and spleen in iron-induced rats after administration of DFO and nanoparticles of green tea extract. The research used experimental research design with a post-test only control group. Experimental nano green teas were divided into four treatment groups; no diet, DFO supplementation, nano green tea supplementation, and a combination of both DFO and green tea. Ferritin and glutathione peroxides were used as biochemical parameters, and histopathological pictures of the heart and spleen were recorded. The study showed that there was significant improvement in the rats receiving DFO and nanoparticles of green tea compared with the rats in the no diet group. The study also reported that nano green tea has an effect comparable to DFO.

show abstract

“…In this regard, chemical methods are discouraged [8] as they involve the use of noxious reducing agents and solvents [9]. With the growing awareness about the safe and clean environment the use of green approaches in synthetic processes is gaining much importance [10]. Therefore, several methods have been developed to avoid the use of synthetic/chemical reducing and stabilizing agents [2].…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles: Structural Features andIn VivoandIn VitroTherapeutic Effects againstHelicobacter pyloriInduced Gastritis

Amin

Hameed

Ali

et al. 2014

Bioinorganic Chemistry and Applications

View full text Add to dashboard Cite

This study evaluates in vivo and in vitro anti-Helicobacter pylori (H. pylori) efficacy of silver nanoparticles (Ag-NPs) prepared via a cost-effective green chemistry route wherein Peganum harmala L. seeds extract was used as a reducing and capping agent. The structural features, as elucidated by surface plasmon resonance spectrophotometry, transmission electron microscopy, and powder X-ray diffraction spectroscopy, revealed the Ag-NPs synthesized to be polydispersed in nature and spherical in shape with 5–40 nm size. A typical Ag-NPs suspension (S5), with size being 15 nm, when tested in vitro against forty-two local isolates and two reference strains, showed a considerable anti-H. pylori activity. In case of in vivo trial against H. pylori induced gastritis, after oral administration of 16 mg/kg body weight of S5 for seven days, a complete clearance was recorded in male albino rates. In comparative time-killing kinetics, S5 exhibited dose- and time-dependent anti-H. pylori activity that was almost similar to tetracycline and clarithromycin, less than amoxicillin, but higher than metronidazole. Furthermore, S5 was found to be an equally effective anti-H. pylori agent at low (≤4) and high pH with no drug resistance observed even up to 10 repeated exposures while a significant drug resistance was recorded for most of the standard drugs employed. The present results revealed the potential of the synthesized Ag-NPs as safer bactericidal agents for the treatment of H. pylori induced gastritis.

show abstract

Green Chemistry and the Health Implications of Nanoparticles

Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Cited by 86 publications

References 1 publication

Biosynthesis of Silver Nanoparticles from Protium serratum and Investigation of their Potential Impacts on Food Safety and Control

Biosynthesis of Silver Nanoparticles from Protium serratum and Investigation of their Potential Impacts on Food Safety and Control

Biochemical and histopathological effects of green tea nanoparticles in ironized mouse model

Green Synthesis of Silver Nanoparticles: Structural Features andIn VivoandIn VitroTherapeutic Effects againstHelicobacter pyloriInduced Gastritis

Contact Info

Product

Resources

About