Graphene oxide and dextran capped gold nanoparticles based surface plasmon resonance sensor for sensitive detection of concanavalin A

Huang, Chunfang; Yao, Gui-Hong; Liang, Ru‐Ping; Qiu, Jian‐Ding

doi:10.1016/j.bios.2013.07.002

Cited by 107 publications

(37 citation statements)

References 47 publications

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“…Gold nanoparticles (AuNPs) have drawn remarkable research interest from the past decade owing to their potential applications in developing biosensors and in many other areas of technological front (Syed, 2014;Omidfar et al, 2013;Prakash et al, 2013;Huang et al, 2013). The wide utility of these nanoparticles has prompted to explore different synthesis routes that fit well with their intended applications.…”

Section: Introductionmentioning

confidence: 99%

Alcohol oxidase protein mediated in-situ synthesized and stabilized gold nanoparticles for developing amperometric alcohol biosensor

Chinnadayyala

Santhosh

Singh

et al. 2015

Biosensors and Bioelectronics

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Section: Introductionmentioning

confidence: 99%

Alcohol oxidase protein mediated in-situ synthesized and stabilized gold nanoparticles for developing amperometric alcohol biosensor

Chinnadayyala

Santhosh

Singh

et al. 2015

Biosensors and Bioelectronics

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“…Such nanoparticle-enhanced SPR detection has been used for the detection of proteins (Lyon et al 1998, Pieper-Furst et al 2005, Cao and Sim 2007, Huang et al 2008, Kawaguchi et al 2008, Mitchell and Lowe 2009, Wang et al 2009) and DNA probes (He et al 2000, Bailey et al 2003, Fang et al 2006 and most recently for the study of carbohydrate-lectin interactions (Huang et al 2013). Detection limits ranging from picomolar to attomolar levels, corresponding to a 1000 to 10 7 improvement in sensitivity when compared to standard SPR have been reported utilizing in most cases sandwich-like assay formats.…”

Section: Some Examples Of Gold-nanoparticleamplified Spr Studiesmentioning

confidence: 99%

“…Mercury ions have shown to coordinate to DNA duplexes that feature thymine-thymine base pair mismatches. Hairpin DNA probes containing a 21 mer T-rich Hg Au NP-based SPR was employed for the sensitive detection of carbohydrate-lectin interactions (Huang et al 2013). …”

Section: '-Oh a -A -( A ) N -A -A A -A -( A ) N -A -A T -T -( T ) N mentioning

confidence: 99%

“…Very recently, Au NP-based SPR was employed for the sensitive detection of carbohydrate-lectin interactions ( Figure 9) (Huang et al 2013). Indeed, with half or more of all proteins containing some carbohydrate motives, the use of a bioanalytical tool allowing glycosignatures to be scrutinized rapidly is without doubt one of the principal driving forces behind the rapid development of SPR-based glyconomics.…”

Section: '-Oh a -A -( A ) N -A -A A -A -( A ) N -A -A T -T -( T ) N mentioning

confidence: 99%

“…Sensitive detection of Con A in the range of 1-20 μg/ml with a detection limit of 0.39 μg/ml was reported. Compared to the direct assay format, the sandwich SPR sensors led to an improvement of 28.7-fold in the sensitivity (Huang et al 2013). …”

Section: '-Oh a -A -( A ) N -A -A A -A -( A ) N -A -A T -T -( T ) N mentioning

confidence: 99%

See 2 more Smart Citations

Surface plasmon resonance: signal amplification using colloidal gold nanoparticles for enhanced sensitivity

Szunerits

Spadavecchia

Boukherroub

2014

Reviews in Analytical Chemistry

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Among all the detection methods developed for bioassays, optical-based approaches are the most popular techniques. A widely used and accepted bioanalytical technique for routine characterization of molecular recognition events at a solid interface is surface plasmon resonance (SPR) spectroscopy. Compared with other techniques, SPR offers a series of advantages including rapid and real-time analysis, in situ detection, and the possibility to determine kinetic as well as thermodynamic parameters of interacting partners without the requirement of tagging one of the two partners. This method is nowadays used in academic and industrial research laboratories for drug discovery processes, safety, and quality control applications as well as for understanding bioaffinity reactions. Past studies have shown that SPR can detect approximately 100 ng/l of proteins. Currently, much effort is still invested to further improve SPR with respect to the sensitivity in the detection of low molecular weight analytes as well as in the detection limit for different analyte/ ligand reactions. This review will focus on the use of gold nanoparticles as an amplification strategy in SPR sensing. Compared to other review articles highlighting the several synthetic routes and properties of gold nanoparticles and research utilizing gold nanoparticles for various sensing strategies, this review will exclusively look at the impact of gold nanostructures for ultrasensitive SPR sensing. Signal enhancement by gold nanoparticles is caused by several effects such as surface mass increase due to enhanced surface area, larger refractive index changes by the particle mass, themselves, and electromagnetic field coupling between the plasmonic properties of the particles (localized surface plasmon resonance) and propagating plasmons. The unique optical, electronic, and catalytic properties of gold nanoparticles put them into the forefront of interest for signal amplification as will be outlined here.

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Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes

Dosekova

Filip

Bertók

et al. 2016

Medicinal Research Reviews

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This review comprehensively covers the most recent achievements (from 2013) in the successful integration of nanomaterials in the field of glycomics. The first part of the paper addresses the beneficial properties of nanomaterials for the construction of biosensors, bioanalytical devices, and protocols for the detection of various analytes, including viruses and whole cells, together with their key characteristics. The second part of the review focuses on the application of nanomaterials integrated with glycans for various biomedical applications, that is, vaccines against viral and bacterial infections and cancer cells, as therapeutic agents, for in vivo imaging and nuclear magnetic resonance imaging, and for selective drug delivery. The final part of the review describes various ways in which glycan enrichment can be effectively done using nanomaterials, molecularly imprinted polymers with polymer thickness controlled at the nanoscale, with a subsequent analysis of glycans by mass spectrometry. A short section describing an active glycoprofiling by microengines (microrockets) is covered as well.

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Graphene oxide and dextran capped gold nanoparticles based surface plasmon resonance sensor for sensitive detection of concanavalin A

Cited by 107 publications

References 47 publications

Alcohol oxidase protein mediated in-situ synthesized and stabilized gold nanoparticles for developing amperometric alcohol biosensor

Alcohol oxidase protein mediated in-situ synthesized and stabilized gold nanoparticles for developing amperometric alcohol biosensor

Surface plasmon resonance: signal amplification using colloidal gold nanoparticles for enhanced sensitivity

Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes

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