Graphene Enhanced Leaky Mode Resonance in Tilted Fiber Bragg Grating: A New Opportunity for Highly Sensitive Fiber Optic Sensor

Li, Zhihong; Yu, Zhuying; Shen, Yubing; Ruan, Xiukai; Dai, Yuxing

doi:10.1109/access.2019.2901517

Cited by 20 publications

(14 citation statements)

References 36 publications

(67 reference statements)

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“…In the scope of detection, optical fiber sensors find their place in a lot of applications involving real-time and continuous monitoring [1][2][3]. The area of implantation is very wide with plenty of opportunities, in particular for the development of strain, temperature, pressure, chemical and bio-chemical sensors [4][5][6][7][8][9]. Many interesting ways exist to achieve the development of an optical fiber sensor for which the most frequently encountered designs include unclad fibers, U-bent fibers [10], etched fibers [11], tapered fibers [12] and fiber gratings [4][5][6][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

“…The area of implantation is very wide with plenty of opportunities, in particular for the development of strain, temperature, pressure, chemical and bio-chemical sensors [4][5][6][7][8][9]. Many interesting ways exist to achieve the development of an optical fiber sensor for which the most frequently encountered designs include unclad fibers, U-bent fibers [10], etched fibers [11], tapered fibers [12] and fiber gratings [4][5][6][13][14][15]. In these aforementioned configurations, tilted fiber Bragg gratings (TFBGs) represent a particularly convenient and relevant solution for biochemical and/or medical sensing once coupled to surface plasmon resonance (SPR) and bioreceptors immobilization (antibodies, aptamers, enzymes, etc) [16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings

Lobry¹,

Loyez²,

Chah³

et al. 2020

Biomed. Opt. Express

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In the biomedical detection context, plasmonic tilted fiber Bragg gratings (TFBGs) have been demonstrated to be a very accurate and sensitive sensing tool, especially well-adapted for biochemical detection. In this work, we have developed an aptasensor following a triple strategy to improve the overall sensing performances and robustness. Single polarization fiber (SPF) is used as biosensor substrate while the demodulation is based on tracking a peculiar feature of the lower envelope of the cladding mode resonances spectrum. This method is highly sensitive and yields wavelength shifts several tens of times higher than the ones reported so far based on the tracking of individual modes of the spectrum. An amplification of the response is further performed through a sandwich assay by the use of specific antibodies. These improvements have been achieved on a biosensor developed for the detection of the HER2 (Human Epidermal Growth Factor Receptor-2) protein, a relevant breast cancer biomarker. These advanced developments can be very interesting for point-of-care biomedical measurements in a convenient practical way.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings

Lobry¹,

Loyez²,

Chah³

et al. 2020

Biomed. Opt. Express

View full text Add to dashboard Cite

show abstract

“…Optical fiber sensors are involved in numerous sensing applications for which continuous monitoring is required [1][2][3]. Possibilities in sensor designs are manifold: strain, temperature, pressure, chemical, and bio-chemical sensors can be achieved, among other applications [4][5][6][7][8][9][10][11]. The latter two are usually derived from the use of an optical fiber as a refractometer [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Multimodal plasmonic optical fiber grating aptasensor

et al. 2020

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Tilted fiber Bragg gratings (TFBGs) are now a well-established technology in the scientific literature, bringing numerous advantages, especially for biodetection. Significant sensitivity improvements are achieved by exciting plasmon waves on their metal-coated surface. Nowadays, a large part of advances in this topic relies on new strategies aimed at providing sensitivity enhancements. In this work, TFBGs are produced in both single-mode and multimode telecommunication-grade optical fibers, and their relative performances are evaluated for refractometry and biosensing purposes. TFBGs are biofunctionalized with aptamers oriented against HER2 (Human Epidermal Growth Factor Receptor-2), a relevant protein biomarker for breast cancer diagnosis. In vitro assays confirm that the sensing performances of TFBGs in multimode fiber are higher or identical to those of their counterparts in single-mode fiber, respectively, when bulk refractometry or surface biosensing is considered. These observations are confirmed by numerical simulations. TFBGs in multimode fiber bring valuable practical assets, featuring a reduced spectral bandwidth for improved multiplexing possibilities enabling the detection of several biomarkers.

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“…Chikh-Bled et al experimentally analyzed the behaviors of ELFBG for both polarizations at high temperature [15], and the transmission spectra of ELFBG depend strongly on the input polarizations. As demonstrated with TFBG, polarization dependence plays a significant role in the excitation of SPR and interrogation of fiber-gratingbased sensors [16]- [18]. Therefore, it will be important for the sensing application of LFBG to have detailed analyses of its polarization dependent coupling properties, which, however, are not available yet.…”

Section: Introductionmentioning

confidence: 99%

Numerical Analyses of the Polarization Dependent Cladding Mode Coupling in Localized Fiber Bragg Gratings

Shen

Zhang

2021

IEEE Access

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The polarization dependence of cladding mode coupling in fiber Bragg grating (FBG) plays a significant role in the excitation of surface plasmon resonances (SPR) for sensing applications. In this work, we numerically analyze the polarization dependent cladding mode coupling enabled by localized fiber Bragg gratings (LFBGs), focusing on the properties that generate from the modal structures and the position of the localized refractive index modifications (RIMs). Our analyses reveal that, both centric and eccentric LFBGs allow strong coupling to cladding modes. In centric LFBGs, coupling to EH/HE 1,m modes dominates, whereas in eccentric LFBG, additional coupling to high azimuthal order cladding modes is permitted. Strong polarization dependence is found in eccentric LFBG: for certain cladding modes, coupling from one polarization can be suppressed due to the cancellation of negative and positive mode coupling. More interestingly, we found that cladding modes with even and odd azimuthal orders response differently to input polarizations, which accounts for the unique polarization dependence (i.e., neighboring resonances exhibit opposite polarization preference in the transmission spectra) in eccentric LFBG. Our numerical results can be verified by the good agreement with existed experimental reports.

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Graphene Enhanced Leaky Mode Resonance in Tilted Fiber Bragg Grating: A New Opportunity for Highly Sensitive Fiber Optic Sensor

Cited by 20 publications

References 36 publications

HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings

HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings

Multimodal plasmonic optical fiber grating aptasensor

Numerical Analyses of the Polarization Dependent Cladding Mode Coupling in Localized Fiber Bragg Gratings

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