Graphene-based nanomaterials: the promising active agents for antibiotics-independent antibacterial applications

Xia, Mao; Yu, Xianzhong; Chen, Yu; Chen, Ge-Yun; Li, Yuan-Hong; Zhang, Ting; Peng, Qiang

doi:10.1016/j.jconrel.2019.06.011

Cited by 175 publications

(91 citation statements)

References 193 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The reduction of GO functional groups results in rGO. The structure of rGO is similar to that of GR, and it is associated with its higher electrical conductivity compared to GO [5,22,28]. Simultaneously, due to the lower content of oxygen-containing functional groups, it is more hydrophobic.…”

Section: Graphene-based Materialsmentioning

confidence: 95%

“…The terms GBMs or graphene family nanomaterial (GFNs) includes GR and its derivatives, such as GO, rGO, GR/GO dots (GD/GOD), GR nano-onions, and GR nano-ribbons, as well as fullerenes, and CNTs, see Figure 2 [10,11]. groups, while at the edges of the flakes there are carboxylic groups [18,22,23]. This composition is a reason for the aforementioned hydrophilicity, the good aqueous dispersity, and the excellent ability to easily cross cell membranes.…”

Section: Graphene-based Materialsmentioning

confidence: 99%

“…The GO flakes consist of a typical graphenic planar structure, composed of sp 2 carbon atoms that is disrupted by the presence of carbon atoms in the sp 3 hybridization state. While on the planar surface, there are mainly hydroxyl and epoxy functional groups, while at the edges of the flakes there are carboxylic groups [18,22,23]. This composition is a reason for the aforementioned hydrophilicity, the good aqueous dispersity, and the excellent ability to easily cross cell membranes.…”

Section: Graphene-based Materialsmentioning

confidence: 99%

See 2 more Smart Citations

Graphenic Materials for Biomedical Applications

Plachá

Jampílek

2019

Nanomaterials

View full text Add to dashboard Cite

Graphene-based nanomaterials have been intensively studied for their properties, modifications, and application potential. Biomedical applications are one of the main directions of research in this field. This review summarizes the research results which were obtained in the last two years (2017-2019), especially those related to drug/gene/protein delivery systems and materials with antimicrobial properties. Due to the large number of studies in the area of carbon nanomaterials, attention here is focused only on 2D structures, i.e. graphene, graphene oxide, and reduced graphene oxide.

show abstract

Section: Graphene-based Materialsmentioning

confidence: 95%

Section: Graphene-based Materialsmentioning

confidence: 99%

Section: Graphene-based Materialsmentioning

confidence: 99%

See 1 more Smart Citation

Graphenic Materials for Biomedical Applications

Plachá

Jampílek

2019

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…One of the most widely used graphene derivatives is graphene oxide. The structure of this nanomaterial consists in graphene sheets with stoppages of sp 3 hybrid carbon atoms with functional groups such as hydroxyl and epoxy groups in the surface and carboxylic groups at the edges [39][40][41]. Therefore, GO presents higher hydrophilicity than G and it can be better dispersed in aqueous media.…”

Section: Graphenic Nanofillersmentioning

confidence: 99%

Extrusion of Polymer Nanocomposites with Graphene and Graphene Derivative Nanofillers: An Overview of Recent Developments

et al. 2020

View full text Add to dashboard Cite

This review is focused on the recent developments of nanocomposite materials that combine a thermoplastic matrix with different forms of graphene or graphene oxide nanofillers. In all cases, the manufacturing method of the composite materials has been melt-processing, in particular, twin-screw extrusion, which can then be followed by injection molding. The advantages of this processing route with respect to other alternative methods will be highlighted. The results point to an increasing interest in biodegradable matrices such as polylactic acid (PLA) and graphene oxide or reduced graphene oxide, rather than graphene. The reasons for this will also be discussed.

show abstract

“…For instance, Zheng et al established a synergistic antibacterial agent through assembly of paramagnetic Ho ions and Au NCs onto graphene oxide (GO) nanosheets (Zheng K. et al, 2019). GO is a new type of antibiotic substance combined with multiple mechanisms, and its rich functional groups enable the functionalization of nanomaterials to further ameliorate antimicrobial performances (Ji et al, 2016;Xia et al, 2019). The assembled nanostructures could be effectively piercing the bacteria.…”

Section: Au Ncs-containing Combination Systemsmentioning

confidence: 99%

Gold Nanoclusters for Bacterial Detection and Infection Therapy

et al. 2020

View full text Add to dashboard Cite

Infections caused by antibiotic-resistant bacteria have become one of the most serious global public health crises. Early detection and effective treatment can effectively prevent deterioration and further spreading of the bacterial infections. Therefore, there is an urgent need for time-saving diagnosis as well as therapeutically potent therapy approaches. Development of nanomedicine has provided more choices for detection and therapy of bacterial infections. Ultrasmall gold nanoclusters (Au NCs) are emerging as potential antibacterial agents and have drawn intense attention in the biomedical fields owing to their excellent biocompatibility and unusual physicochemical properties. Recent significant efforts have shown that these versatile Au NCs also have great application potential in the selective detection of bacteria and infection treatment. In this review, we will provide an overview of research progress on the development of versatile Au NCs for bacterial detection and infection treatment, and the mechanisms of action of designed diagnostic and therapeutic agents will be highlighted. Based on these cases, we have briefly discussed the current issues and perspective of Au NCs for bacterial detection and infection treatment applications.

show abstract

Graphene-based nanomaterials: the promising active agents for antibiotics-independent antibacterial applications

Cited by 175 publications

References 193 publications

Graphenic Materials for Biomedical Applications

Graphenic Materials for Biomedical Applications

Extrusion of Polymer Nanocomposites with Graphene and Graphene Derivative Nanofillers: An Overview of Recent Developments

Gold Nanoclusters for Bacterial Detection and Infection Therapy

Contact Info

Product

Resources

About