Graphene-based biosensors

Лебедев, А. А.; Davydov, V. Yu.; Новиков, С. Н.; Litvin, D. P.; Makarov, Yu.N.; Климович, В. Б.; Самойлович, М. П.

doi:10.1134/s1063785016070233

Cited by 18 publications

(6 citation statements)

References 9 publications

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“…The physical basis of such a sensor is the plasma resonancefluctuation of surface electromagnetic waves (so-called plasmonsquasi-particles appearing to be electronic gas fluctuation quantum), emerging at the border dividing two environments of different optical properties. This effect leads to deflection index changes and multiplication of signal expression determined, for example, upon immunofluorescence [9,10]. One of the challenging techniques based on the principle described supposes the interaction of specific antibodies immobilized upon graphene or its oxide with antigens as target-cells.…”

Section: Discussionmentioning

confidence: 99%

Secure application of graphene in medicine

Savicheva

Tapilskaya

Spasibova

et al. 2020

Gynecological Endocrinology

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Section: Discussionmentioning

confidence: 99%

Secure application of graphene in medicine

Savicheva

Tapilskaya

Spasibova

et al. 2020

Gynecological Endocrinology

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“…Именно такие вопросы можно попытаться решить при использовании графена, за открытие которого К. Новоселову и А. Гейму в 2010 г. была присуждена Нобелевская премия. Сочетание его свойств обеспечивает значимое изменение электропроводимости графена при осаждении на нем даже незначительных, исчезающе малых концентраций посторонних веществ [15,16]. Это определяет попытки разработки биосенсоров на основе графена для диагностики различных заболеваний, в том числе и болезни Альцгеймера.…”

Section: основная частьunclassified

Graphene as the basis of biological sensors for the diagnosis of neurodegenerative dementia

Vorobev

Ternovykh

Lebedev

et al. 2022

Russian Military Medical Academy Reports

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Cognitive disorders are currently being considered within the framework of the most pressing problems of modern clinical neurology in particular and medicine in general. Their significance is due to both the significant negative impact on the health and quality of life of patients, as well as the condition of their immediate relatives and society as a whole. In addition, widespread violations of higher cortical functions significantly affect the financial and economic indicators of individual groups of individuals and the state. These provisions determine the need to search for new highly effective ways of managing patients. The solution of this problem is impossible without the introduction of effective diagnostic methods that allow rapid and qualitative verification of the pathological process, especially at its early stages. Given the fact that Alzheimers disease plays a major role in the development of dementia in old age, the development of its diagnostic methods is the interest area for the researchers. Currently used diagnostic algorithms, which include, in addition to neuropsychological examination, such methods as the study of the content of -amyloid and -protein in the cerebrospinal fluid, positron emission tomography, a number of others are either invasive or require expensive specialized equipment and have a high financial cost. This leads to a significant limitation of their use in everyday clinical practice. At the same time, certain successes have been achieved recently in the field of the introduction of nanotechnology products into medical science. This is the direction for the further prospects for the development of diagnostic and therapeutic strategies. One of the materials obtained in this direction is graphene, which is a two-dimensional allotropic modification of carbon with a number of specific physical properties. Currently biological sensors based on graphene are being developed, which have high sensitivity and specificity to the biomarkers under study and allow them to be determined in extremely low concentrations. The research in this direction may lead to the creation of a new diagnostic method that allows for the effective diagnosis of Alzheimers disease in the early stages, including at the outpatient level.

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“…The attached gas molecules, depending on their charge and type of conductivity of the graphene film, behave as donors or acceptors, i.e., they change the concentration of mobile charge carriers. As a result, depending on the type of adsorbed molecule, a decrease or increase in the film resistance was observed [59][60]. It should be noted that one of the serious drawbacks of the graphene gas sensor is the lack of selectivity.…”

Section: Thermal Managementmentioning

confidence: 99%

Unique Properties of Graphene

Kudaibergenova¹,

Аisha²,

Saule³

et al. 2020

THE ACADEMY OF SCIENCES OF THE REPUBLIC OF KAZAKHSTAN JSC «D.V.

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News of the Academy of sciences of the Republic of Kazakhstan 2 NAS RK is pleased to announce that News of NAS RK. Series of chemistry and technologies scientific journal has been accepted for indexing in the Emerging Sources Citation Index, a new edition of Web of Science. Content in this index is under consideration by Clarivate Analytics to be accepted in the Science Citation Index Expanded, the Social Sciences Citation Index, and the Arts & Humanities Citation Index. The quality and depth of content Web of Science offers to researchers, authors, publishers, and institutions sets it apart from other research databases. The inclusion of News of NAS RK. Series of chemistry and technologies in the Emerging Sources Citation Index demonstrates our dedication to providing the most relevant and influential content of chemical sciences to our community. Қазақстан Республикасы Ұлттық ғылым академиясы "ҚР ҰҒА Хабарлары. Химия және технология сериясы" ғылыми журналының Web of Science-тің жаңаланған нұсқасы Emerging Sources Citation Index-те индекстелуге қабылданғанын хабарлайды. Бұл индекстелу барысында Clarivate Analytics компаниясы журналды одан әрі the Science Citation Index Expanded, the Social Sciences Citation Index және the Arts & Humanities Citation Index-ке қабылдау мәселесін қарастыруда. Webof Science зерттеушілер, авторлар, баспашылар мен мекемелерге контент тереңдігі мен сапасын ұсынады. ҚР ҰҒА Хабарлары. Химия және технология сериясы Emerging Sources Citation Index-ке енуі біздің қоғамдастық үшін ең өзекті және беделді химиялық ғылымдар бойынша контентке адалдығымызды білдіреді. НАН РК сообщает, что научный журнал «Известия НАН РК. Серия химии и технологий» был принят для индексирования в Emerging Sources Citation Index, обновленной версии Web of Science. Содержание в этом индексировании находится в стадии рассмотрения компанией Clarivate Analytics для дальнейшего принятия журнала в the Science Citation Index Expanded, the Social Sciences Citation Index и the Arts & Humanities Citation Index. Web of Science предлагает качество и глубину контента для исследователей, авторов, издателей и учреждений. Включение Известия НАН РК в Emerging Sources Citation Index демонстрирует нашу приверженность к наиболее актуальному и влиятельному контенту по химическим наукам для нашего сообщества.

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Graphene-based biosensors

Cited by 18 publications

References 9 publications

Secure application of graphene in medicine

Secure application of graphene in medicine

Graphene as the basis of biological sensors for the diagnosis of neurodegenerative dementia

Unique Properties of Graphene

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