Granulomatous Pigmented Purpuric Dermatitis Associated with Primary Sjögren’s Syndrome

Generalized Granulomatous Dermatitis Accompanied by Myelodysplastic Syndrome

“…Moreover, they reported in another study that the Th17:Treg ratio was significantly higher in low-risk MDS compared with highrisk MDS (4). on the other hand, we recently reported the distribution of Foxp3 + Tregs and IL-17-producing cells in several cases of cutaneous granulomatous dermatitis, including sarcoidosis, granuloma annulare, necrobiosis lipoidica, granulomatous pigmented and purpuric dermatitis (8)(9)(10). on the other hand, we recently reported the distribution of Foxp3 + Tregs and IL-17-producing cells in several cases of cutaneous granulomatous dermatitis, including sarcoidosis, granuloma annulare, necrobiosis lipoidica, granulomatous pigmented and purpuric dermatitis (8)(9)(10).…”

Pigmented Purpuric Dermatosis Associated with Primary Antiphospholipid Syndrome

“…Various medications (NSAIDs, steroids, sildenafil, glipizide, bezafibrate), food additives, external contact agents and infections have been suggested to play roles in the etiology of PPD (4-6). PPD also manifests as skin involvement in some hematological, oncological, immunological and infectious diseases, such as hepatitis C (7,8). In the present case, we ruled out the presence of hematological, oncological, immunological and infectious diseases in addition to primary and secondary vasculitic syndromes and coagulopathies.…”

Pigmented Necrobiosis Lipoidica Accompanied by Insulin-dependent Diabetes Mellitus Induces CD163 Proinflammatory Macrophages and Interleukin-17-producing Cells

“…Foxp3, a member ofthe forkhead family transcription factor, is both necessary and sufficient for their development and function (4). Tregs are currently being examined for their roles in the pathogenesis of human diseases, including granulomatous disorders (11,12).…”