Abstract:The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small-to medium-sized blood vessels. The pathology of granulomatosis with polyangiitis (GPA) typically features a granulomatous and sometimes necrotizing vasculitis targeting predominantly the respiratory tract and kidneys, including necrotizing granulomatous inflammation. The diagnosis can be delayed due to the nonspecific nature of the symptoms. Cyclophosphamide and gluco… Show more
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