Granular cell tumor of the breast: mammographic and histologic correlation

Vos, Louwerens D.; Tham, Richard; Vroegindeweij, Dammis; Vrints, L. W.

doi:10.1016/0720-048x(94)00568-w

Cited by 7 publications

(6 citation statements)

References 12 publications

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“…On mammography granular cell tumor of the breast is difficult to distinguish from carcinoma [8], forming typical stellate mass lacking calcifications with the dense core [9]. Ultrasound usually reveals a solid mass with posterior shadowing suggestive of carcinoma [9].…”

Section: Discussionmentioning

confidence: 99%

“…The difference between granular cell tumor and granulomatous inflammatory reaction or a histiocytic tumor is negativity for histiocyte-associated antigens, but reactivity for CD68 has been described in granular cell tumor [13] as in our case. Granular cell tumor must be distinguished from metastatic neoplasm in the breast that have oncocytic or clear cell features, such as renal carcinoma, malignant melanoma and alveolar soft part sarcoma [8]. …”

Section: Discussionmentioning

confidence: 99%

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Granular cell tumor of the breast: a case report and review of literature

Filipovski

Banev

Janevska

et al. 2009

Cases J

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A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Granular cell tumor of the breast: a case report and review of literature

Filipovski

Banev

Janevska

et al. 2009

Cases J

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“…On mammography, GCT of the breast may present as round, circumscribed lesions as distinct densities, or as stellated masses difficult to distinguish from malignancy 4 5. On ultrasound it usually reveals as a solid mass with posterior shadowing 4.…”

Section: Discussionmentioning

confidence: 99%

“…Mammographically, it is difficult to distinguish from carcinoma, forming a typical stellate mass lacking calcifications 4. Ultrasound usually reveals a solid mass with posterior shadowing suggestive of carcinoma 4 5. Sonographically guided biopsy of the lesion is the diagnostic procedure of choice 4 6.…”

Section: Differential Diagnosismentioning

confidence: 99%

Granular cell breast tumour mimicking infiltrating carcinoma

et al. 2013

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Granular cell tumour (GCT) is a rare, usually benign neoplasm that can mimic carcinoma on breast imaging. GCT can originate anywhere in the body but is most frequently found in the head and neck region, particularly in the tongue. Of the reported cases, 6% have occurred in the breast, most commonly in the upper inner quadrant. We report a case of GCT of the breast presenting as a spiculated mass infiltrating the greater thoracic muscle on breast screening mammogram.

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“…Irregularity, spiculations, isodensity sometimes associated with hypodense rims and heterogenicity are commonly observed, forming typical stellate mass lacking calcifications within the dense core [11]. Ultrasound usually reveals a solid mass with posterior shadowing suggestive of carcinoma [12]. Rarely the ultrasound pattern is hypoechoic with or without attenuation of the sound beam [13].…”

Section: Review Of Literaturementioning

confidence: 99%

Granular Cell Tumor of Breast: a Case Report and Review of Literature

Rexeena

Augustine

Nitish

et al. 2015

Indian J Surg Oncol

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This is an article reporting a case of granular cell tumor in the left breast in a 58 year old lady. Patient presented with a 3 × 3 cm mass in the left breast. Mammography reported a BIRADS 5 lesion in the left breast. With a clinical and radiological diagnosis of malignancy, patient was sent for FNAC (Fine needle aspiration Cytology). The cytology report was granular cell tumor. Following this patient underwent wide excision of the mass. Histopathology confirmed the cytological diagnosis of granular cell tumor of the breast. Patient is on regular follow up and is presently free of disease. The case report is followed up by a brief review of literature of granular cell tumor of the breast.Keywords Granular cell tumor . Breast . Excision Case ReportA 58 year old multiparous post menopausal lady presented with a history of lump in left breast since the past 3 months. Patient was initially evaluated in a local hospital. FNAC from the left breast lesion done outside was reported as lobular carcinoma of the breast. With this report patient was referred to our centre. On examination patient was ECOG 0. General and systemic examination of the patient was normal. On examination the left breast revealed a well defined firm lump measuring 3 × 3 cm in the upper inner quadrant without skin or chest wall fixity. No axillary or supraclavicular lymphadenopathy was present. Right breast and axilla were normal. Mammography revealed an irregular BIRADS 5 lesion in the left breast and normal right breast (Fig. 1). The patient underwent FNAC at our centre. The cytology smears showed clusters of cells with moderate to abundant granular eosinophilic cytoplasm and bland vesicular nucleus (Fig. 2) and the cytological diagnosis was granular cell tumor. As our pathologist is very experienced and in keeping with the local protocol we proceeded with a wide excision and frozen section on

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Granular cell tumor of the breast: mammographic and histologic correlation

Cited by 7 publications

References 12 publications

Granular cell tumor of the breast: a case report and review of literature

Granular cell tumor of the breast: a case report and review of literature

Granular cell breast tumour mimicking infiltrating carcinoma

Granular Cell Tumor of Breast: a Case Report and Review of Literature

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