Gonadotropins regulate cadherin expression in the ovary of the chicken embryo (Gallus gallus)

Günther, Jeannette; Díaz, Verónica Araiza; Pedernera, E.; Méndez, C.

doi:10.1016/j.ygcen.2011.09.012

Cited by 4 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cortical structures (cortical cords and germ cells) are shifted from the outermost layer toward the medulla. This change in morphology was evidenced by the immunolocalization of cytokeratins and N-cadherin, two proteins known to be present in the ovarian cortex (Ishimaru et al 2008;Gü nther et al 2011). Previous studies have demonstrated that in organ culture both TGFb1 and TGFb2 reduced the number of ovarian somatic cells without affecting the number of germ cells.…”

Section: Discussionmentioning

confidence: 96%

Transforming growth factor β mRNA and protein expression in the ovary of the chicken embryo

et al. 2012

Self Cite

View full text Add to dashboard Cite

The expression pattern of transforming growth factor beta (TGFβ) isoforms in chicken embryo gonads was studied at 6-10 days of incubation. TGFβ2 mRNA was expressed predominantly in the cortex of the left ovary from day 8 of incubation onwards. TGFβ3 mRNA was not detected at any of the stages studied. Similarly, immunofluorescence for the TGFβ protein revealed that at day 9 it was located throughout the cortex of the left ovary and in the medulla of both the left and right ovaries. The presence of phosphorylated Smad2 in the nuclei of these regions suggests that TGFβ signaling is most likely active at this developmental stage. Culturing the left ovary in a TGFβ1-supplemented medium induced a shift of cortical structures toward the medulla, suggesting a role for TGFβ in the morphogenesis of the female gonad in chickens.

show abstract

Section: Discussionmentioning

confidence: 96%

Transforming growth factor β mRNA and protein expression in the ovary of the chicken embryo

et al. 2012

Self Cite

View full text Add to dashboard Cite

show abstract

“…In addition to the PI3K/Akt signaling pathway, cadherin is also related to Notch signaling in neurogenesis (Hatakeyama et al, ). E‐ and N‐cadherin are also expressed in chicken ovaries (Gunther et al, ). Therefore, we examined the expression of E‐ and N‐cadherin mRNAs.…”

Section: Discussionmentioning

confidence: 99%

Involvement of Notch signaling in early chick ovarian follicle development

Zhao

Guo

et al. 2015

Cell Biology International

View full text Add to dashboard Cite

The formation of primordial follicles is a crucial process in the establishment of follicle pools required for the female's reproductive life span. For laying hens, ample follicles are a prerequisite for high laying performance. Notch signaling plays critical roles in germ cell cysts breakdown and in the formation of primordial follicles. Here, we investigated the role of Notch signaling in the ovarian development of post-hatch chicks. Results showed that around post-hatch day 4 (H4), the germ cell cysts broke apart, oocytes became surrounded by squamous pregranulosa cells, and the primordial follicles were then formed. Subsequently, we detected the expression of Notch signaling-related genes including Notch receptors (Notch1, 2), ligands (Jag1, 2 and Dll1, 4), and target genes (Hes1, Hey1). These genes all showed expression at H4 and some of these genes were up-regulated during primordial follicle formation. To evaluate the Notch signaling requirement for early follicular development, we adopted an in vitro ovary culture system. Suppression of Notch signaling by γ-secretase inhibitor induced a decrease of primordial follicles and an increase of germ cells in cysts. Attenuating Notch signaling also inhibited the phosphatidylinositol 3-kinase/protein kinase B pathways and suppressed cadherin expression. These results suggest that Notch signaling is endowed with an indispensable role in primordial follicle formation in post-hatch chicks.

show abstract

“…The expression of cadherins in chicken embryos has been mapped and reported by different groups [30,39,[41][42][43]. In the chicken embryonic brain, the expression and regulation of cadherins was studied during development [44][45][46].…”

Section: Regional Expression Of Cadherin Mrnas In Subdivisions Of Thementioning

confidence: 99%

Distribution of Cadherin in the Parahippocampal Area of Developing Domestic Chicken Embryos

Wang

Lin

et al. 2020

Exp Neurobiol

View full text Add to dashboard Cite

Hippocampal formation is important in spatial learning and memory [1]. However, the molecular and cytoarchitecture bases are still not clear in evolution, and the homology between avian and mammalian species needs to be clarified [2, 3]. Avian hippocampal formation includes the hippocampus and the parahippocampal area (APH). This formation occurs in the medial and dorsomedial pallium and extends laterally to part of the caudolateral pallium. The avian APH does not have clear boundaries with the hippocampus. Hippocampal formation was divided into the hippocampus and APH first [2, 4]. Later, hippocampal formation was divided into seven subdivisions in other studies based on the different immunoactivities of neural peptides antibodies [5, 6]. Some researchers subsequently divided hippocampal formation into five subdivisions: dorsomedial (DM) [7], dorsolateral (DL), ventral core, ventrolateral area of the V-shaped layer and ventromedial area of the V-shaped layer [8, 9]. Recently, the APH has been considered to correspond to the DM and DL subdivisions (Fig. 1A) [10]. The APH has also been divided into four portions, the medial APH (APHm), the intermediate APH (APHi), the lateral APH (APHl) and the caudolateral APH (APHcl), in chicken embryos (Fig. 1B) [11]. A small portion of the superficial corticoid dorsolateral area is also included in the caudolateral APH part [12]. The APH is a structure that develops at a later stage during the embryonic period in avian species. This long and thin

show abstract

Gonadotropins regulate cadherin expression in the ovary of the chicken embryo (Gallus gallus)

Cited by 4 publications

References 17 publications

Transforming growth factor β mRNA and protein expression in the ovary of the chicken embryo

Transforming growth factor β mRNA and protein expression in the ovary of the chicken embryo

Involvement of Notch signaling in early chick ovarian follicle development

Distribution of Cadherin in the Parahippocampal Area of Developing Domestic Chicken Embryos

Contact Info

Product

Resources

About