2019
DOI: 10.1038/s41598-019-39138-w
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Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings

Abstract: Multi electrode arrays (MEA) have been exploited in different electrophysiological applications. In neurological applications, MEAs are the vital interfaces between neurons and the electronic circuits with dual role; transmitting electric signal to the neurons and converting neural activity to the electric signal. Since the performance of the electrodes has a direct effect on the quality of the recorded neuronal signal, as well as the stimulation, the true choice of electrode material for MEA is crucial. Gold … Show more

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Cited by 31 publications
(22 citation statements)
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References 48 publications
(36 reference statements)
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“…Here, the overall quality of the core/shell layout is determined by controlling the thickness, mechanical modulus, and surface textures of each elastomer layer ( 23 ). The surface of the recording electrodes remains exposed after the encapsulation where a thin Au film (~500 nm) is electroplated to promote the biocompatibility ( 24 ). Details of the fabrication process appear in Materials and Methods.…”
Section: Resultsmentioning
confidence: 99%
“…Here, the overall quality of the core/shell layout is determined by controlling the thickness, mechanical modulus, and surface textures of each elastomer layer ( 23 ). The surface of the recording electrodes remains exposed after the encapsulation where a thin Au film (~500 nm) is electroplated to promote the biocompatibility ( 24 ). Details of the fabrication process appear in Materials and Methods.…”
Section: Resultsmentioning
confidence: 99%
“…The fabrication steps are schematically illustrated in Figure 1 . Briefly, the glass substrate was first subjected to the surface modification to achieve adequate adhesion of the gold layer to the substrates’ surface without the need of adhesive layers ( Vafaiee et al, 2019 ). The glass substrate was chosen in order to provide the necessary mechanical strength during the handling.…”
Section: Methodsmentioning
confidence: 99%
“…Thin films of transition metals such as gold ( Dimaki et al, 2014 ; Vafaiee et al, 2019 ), platinum ( Brummer and Turner, 1977 ; Desai et al, 2010 ), and iridium ( Eick et al, 2009 ; Brunton, 2015 ) are usually used for the construction of microelectrode arrays due to their high conductivity and biocompatibility ( Blau et al, 2011 ). Given the importance of electrode size in the recorded signals, achieving less impedance in electrode construction is the crucial factor.…”
Section: Introductionmentioning
confidence: 99%
“…The entire surface of the Cu-plated Ag flakes were also plated with Au for 2 minutes to promote biocompatibility and improve scratch strength. 21 Next, another direct writing of the formulated ink was followed to define the remaining traces and therefore complete the device in an open mesh layout to ensure breathability and stretchability ( Figure 1d). 22 Finally, a water-soluble medical tape made of polyvinyl alcohol (PVA, Sigma-Aldrich; 50 µm-thick) was applied to gently peel the device from the Si wafer and then trimmed using scissors to remove excess areas ( Figure 1e).…”
Section: Custom Design and Prototyping Of Poroelastic Biosensor Arraymentioning
confidence: 99%