Gold Particles as Templates for the Synthesis of Hollow Polymer Capsules. Control of Capsule Dimensions and Guest Encapsulation

Marinakos, Stella M.; Novak, James P.; Brousseau, Louis; House, A. Blaine; Edeki, E.; Feldhaus, and James C.; Feldheim, Daniel L.

doi:10.1021/ja990945k

Cited by 331 publications

(199 citation statements)

References 34 publications

Supporting

Mentioning

198

Contrasting

Order By: Relevance

“…The electrostatic adsorption of polyelectrolytes [16][17][18] or particles 19 has also been investigated. Capsules have been successfully produced by polymerization in so-called miniemulsions.…”

Section: Nanoparticles As Building Blocksmentioning

confidence: 99%

Self-assembly of nanoparticles at interfaces

et al. 2007

View full text Add to dashboard Cite

Developments in the assembly of nanoparticles at liquid-liquid interfaces are reviewed where the assemblies can be controlled by tuning the size of the nanoparticles and the chemical characteristics of the ligands. Both synthetic and biological nanoparticles are discussed. By controlling the type of ligands, uniform and Janus-type nanoparticles can be produced where, at liquid-liquid interfaces, subsequent reactions of the ligands can be used to generate crosslinked sheets of nanoparticles at the interface that have applications including novel encapsulants, filtration devices with well-defined porosities, and controlled release materials. By controlling the size and volume fraction of the nanoparticles and the chemical nature of the ligands, nanoparticle-polymer composites can be generated where either enthalpy or entropy can be used to control the spatial distribution of the nanoparticles, thereby, producing auto-responsive materials that self-heal, self-corral assemblies of nanoparticles, or self-direct morphologies. Such systems hold great promise for generating novel optical, acoustic, electronic and magnetic materials.

show abstract

Section: Nanoparticles As Building Blocksmentioning

confidence: 99%

Self-assembly of nanoparticles at interfaces

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Preparation of the layer-bylayer assembled ultrathin hollow polymer shells (or nanotubes) has been extensively investigated by Caruso et al [15][16][17][18][19] and by other groups. [20][21][22][23][24][25][26] The preparation of free-standing ultrathin films by this approach has been studied by several groups. Onda et al have prepared enzyme-containing alternate films on porous filter membranes and examined sequential enzyme catalysis.…”

Section: Nanomembrane Formation By Layer-by-layer Assemblymentioning

confidence: 99%

Development of Fabrication of Giant Nanomembranes

Watanabe

Vendamme

Kunitake

2007

Bulletin of the Chemical Society of Japan

View full text Add to dashboard Cite

Large nanomembranes, which are characterized by aspect ratios (size/thickness) of greater than one million, are described. The combination of nanometer thickness and macroscopic size facilitates important applications in materials separation, selective transport and electrochemical devices. In the past, only small pieces of nanomembranes have been fabricated, in spite of intensive research. We describe here the first examples of a general fabrication procedure. Spin coating of the precursor solutions on appropriate underlayer was effectively used to prepare 10-30 nm thick nanomembranes of metal oxides, interpenetrating network of cross-linked acrylate with metal oxide, and highly cross-linked organic polymers (epoxy resin, etc.). The underlayer is composed of an affinity (e.g., poly(vinyl alcohol)) layer and/ or sacrificial layer, and the role of these layers is discussed. Some of the mechanical properties of nanomembranes were measured by using a bulge test and a compression method. The nanomembranes of the organic and inorganic hybrids and the purely organic resins were surprisingly robust and defect-free.

show abstract

“…Coating immiscible templates by electrostatic deposition of alternating layers of charged polymers or particles can be used to fabricate nanoporous capsules (10)(11)(12)(13)(14)(15)(16)(17)(18). Microfabrication technology can be used to create submillimeter-sized silicon capsules with exquisitely precise nanometer-scale holes for selective permeability and slow release (19).…”

mentioning

confidence: 99%

Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles

Dinsmore

Hsu

Nikolaides

et al. 2002

Science

1,971

1,798

View full text Add to dashboard Cite

We present an approach to fabricate solid capsules with precise control of size, permeability, mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of colloidal particles onto the interface of emulsion droplets. After the particles are locked together to form elastic shells, the emulsion droplets are transferred to a fresh continuous-phase fluid that is the same as that inside the droplets. The resultant structures, which we call "colloidosomes," are hollow, elastic shells whose permeability and elasticity can be precisely controlled. The generality and robustness of these structures and their potential for cellular immunoisolation are demonstrated by the use of a variety of solvents, particles, and contents.Efficient encapsulation of active ingredients such as drugs, proteins, vitamins, flavors, gas bubbles, or even living cells is becoming increasingly important for a wide variety of applications and technologies, ranging from functional foods to drug delivery to biomedical applications (1-8). Increasingly sophisticated techniques are being developed to create physical structures that can meet the demanding requirements of these applications. A versatile technique should provide efficient encapsulation in structures whose size, permeability, mechanical strength, and compatibility can be easily controlled. Control of the size allows flexibility in applications and choice of encapsulated materials; control of the permeability allows selective and timed release; control of the mechanical strength allows the yield stress to be adjusted to withstand varying of mechanical loads and to enable release by defined shear rates; and control of compatibility allows encapsulation of fragile and sensitive ingredients, such as biomolecules and cells. Precise control of all these features would allow the strategic design of possible release mechanisms. Ideally, it should be feasible to construct these capsules from a wide variety of inorganic, organic, or polymeric materials to provide flexibility in their uses.A variety of techniques has been developed to address specific encapsulation requirements: Coacervation, or controlled gelation, of polymers at the surface of water drops can be used to fabricate nano-or microporous capsules (1-5, 9); other fluid extrusion methods can also be used to create the polymer coating (6, 7). Coating immiscible templates by electrostatic deposition of alternating layers of charged polymers or particles can be used to fabricate nanoporous capsules (10-18). Microfabrication technology can be used to create submillimeter-sized silicon capsules with exquisitely precise nanometer-scale holes for selective permeability and slow release (19). However, despite the enormous progress in encapsulation technologies, these methods can be limited in their applicability, in the range of materials that can be used, in the uniformity of pore sizes, in the accessible permeabilities and elasticities, or in the ease of synthesis, filling efficiency, and yield. We present a flexi...

show abstract

Gold Particles as Templates for the Synthesis of Hollow Polymer Capsules. Control of Capsule Dimensions and Guest Encapsulation

Cited by 331 publications

References 34 publications

Self-assembly of nanoparticles at interfaces

Self-assembly of nanoparticles at interfaces

Development of Fabrication of Giant Nanomembranes

Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles

Contact Info

Product

Resources

About