Gold nanoparticle-based biosensors

Li, Yuanyuang; Schluesener, Hermann J.; Xu, Shunqing

doi:10.1007/bf03214964

Cited by 441 publications

(254 citation statements)

References 141 publications

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“…1 They can be used as catalysts, sensors, biosensors, and substrates for surface-enhanced Raman spectroscopy (SERS). [2][3][4][5] Au thin films on glass also have the potential to be used as transparent conductive electrodes (TCEs) in solar cells, and infrared reflective coatings for architectural windows. 6,7 Different applications require different properties of the Au thin films.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Electrically Conductive Au Thin Films by Colloid Sedimentation

Petek

Bukovec

Škofic

2015

ACSi

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Dedicated to the memory of Prof. Dr. Jurij V. Bren~i~. AbstractA novel and facile wet-chemical method for the preparation of Au thin films is presented. The Au thin films were deposited on glass substrates by the gravitational sedimentation of Au colloids. The colloids were formed by chemical reduction in ethanol using HAuCl 4 and NaBH 4 with no added surfactants. Without stabilizing agents the colloids quickly aggregated, settled to the bottom and formed a thin film. The sedimentation of the colloids was monitored using UV-vis spectroscopy. Thin films with Au loads ranging between 0.25 and 4.0 g m -2 were prepared and characterized by means of UV-vis spectroscopy, electrical resistance measurements, optical microscopy, scanning electron microscopy, and cyclic voltammetry. The results showed that nanostructured Au films with a very high specific surface area were formed. The films were electrically conductive and partially transparent to visible light.

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Section: Introductionmentioning

confidence: 99%

Preparation of Electrically Conductive Au Thin Films by Colloid Sedimentation

Petek

Bukovec

Škofic

2015

ACSi

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“…Moreover, they are capable of transferring electrons efficiently between different electro-active species and electrode materials. In addition, the light-scattering properties and extremely large enhancement ability of the local electromagnetic field enables GNPs to be used as signal amplification tags in diverse biosensors (Lia et al 2010). Three main types of GNP based biosensors are used: optical, electrochemical and piezoelectric biosensors.…”

Section: Nanoparticle Based Biosensorsmentioning

confidence: 99%

Nanomaterials for biomedical applications

Das

Mitra

Khurana

et al. 2013

Frontiers in Life Science

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Nanotechnology involves understanding and manipulating materials normally in the size range of 1 to 100 nm, where particles show completely novel physico-chemical properties from their bulk counterpart. In the last two decades a number of precisely engineered nanomaterials have been developed for diagnostic and therapeutic applications. For diagnostic applications, nanoparticles allow detection at the molecular scale. Some fluorescent nanohybrids can serve the dual purpose of detection and destruction of pathogenic microbes. The specificity and sensitivity of magnetic resonance imaging can be greatly improved by using nanoparticles as contrast enhancement material. As therapeutic agent, they allow targeted delivery and sustained release of drug molecules and they also have huge potential in tissue engineering. Given the vast range of application of nanomaterials in the biomedical domain, this review focuses on the major nanoparticle based diagnostic and therapeutic modalities.

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“…Herein, three different analytical processes were designed for the investigation. [32][33][34] In the first strategy, GSH and melamine with different concentration were mixed first, followed by the addition of constant AuNPs. In the second strategy, GSH and AuNPs solution was mixed first and allowed to interact for a while, followed by the addition of melamine.…”

Section: Recognition Mechanisms For Both Nanoparticlesmentioning

confidence: 99%

Comparative Studies on the Quick Recognition of Melamine Using Unmodified Gold Nanoparticles and p‐Nitrobenzenesulfonic Grafted Silver Nanoparticles

Bai

Dong

Zhang

et al. 2011

J Chinese Chemical Soc

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Both unmodified gold nanoparticles (AuNPs) and p-nitrobenzenesulfonic (p-NBS) grafted silver nanoparticles (AgNPs) were prepared by chemical synthesis, respectively. They could be used for visual detection via the interaction with the twelve amide compounds including melamine. These color changes could be seen with the naked eye directly and monitored by ultraviolet visible (UV-Vis) absorbance spectra. The recognition mechanism for both nanoparticles was comparatively investigated by the addition of glutathione (GSH) in the presence of melamine, respectively. The triple hydrogen bonding recognition and the attractive van der Waals interactions between melamine (0.5 mg/L) and AuNPs were responsible for the color change during its aggregation (red-to-purple or blue), whilst the electron donor-acceptor interaction between melamine (0.2 mg/L) and p-NBS modified on the surface of AgNPs resulted in the color changes (yellow-to-grey or dark green).

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Gold nanoparticle-based biosensors

Cited by 441 publications

References 141 publications

Preparation of Electrically Conductive Au Thin Films by Colloid Sedimentation

Preparation of Electrically Conductive Au Thin Films by Colloid Sedimentation

Nanomaterials for biomedical applications

Comparative Studies on the Quick Recognition of Melamine Using Unmodified Gold Nanoparticles and p‐Nitrobenzenesulfonic Grafted Silver Nanoparticles

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