Gold(I) complexes with multifunctional phosphane ligands: Synthesis and catalysis

Hydroamination of alkynes catalyzed by NHC-Gold(I) complexes: the non-monotonic effect of substituted arylamines on the catalyst activity

“…Due to their carbophilicity and Lewis acidity, gold(I) and gold (III) complexes have recently received increased attention and have been used in homogeneous phase catalytic reactions to activate multiple C-C bonds that could undergo nucleophilic attack ( Campeau et al, 2021 ). The most studied reactions are those that lead to the synthesis of nitrogen-containing heterocycles, the hydration ( Biasiolo et al, 2015 ; Gatto et al, 2016 ; 2018b ), alkoxylation ( Gatto et al, 2018a ), or hydroarylation ( Tubaro et al, 2013 ; Baron and Biffis, 2019 ; Leung et al, 2020 ; Biffis et al, 2021 ) reactions of alkynes and the A 3 (alkyne, aldehyde, and amine) coupling reactions ( Visbal et al, 2018 ). Gold complexes can also catalyze the addition of an amine to an alkyne ( Duan et al, 2009 ; Liu and Che, 2009 ; Alvarado et al, 2012 ; Sarcher et al, 2012 ; Gonell et al, 2013 ).…”

Gold-catalyzed hydroarylation reactions: a comprehensive overview

“…The Biffis group synthesized two gold(I)-catalysts [L 22 AuCl] and [L 23 AuCl] containing multifunctional phosphane ligands and described a hydroarylation reaction with the help of these catalysts (Scheme 79). 100 Due to its more electron-deficient character, the gold(I)-complex with the cationic phosphane ligand facilitated the hydroarylation of ethyl propiolate with mesitylene. Under neutral conditions, gold(I)-complexes in ionic liquids have recently been discovered and behaved as an efficient catalyst for this process.…”

An efficient catalytic method for hydrophosphination of heterocumulenes with diethylzinc as precatalyst without a solvent

“…These organophosphorus compounds are widely used as stabilizing ligands for various metal compounds. [26][27][28][29] Hydrophosphination and Hydrophosphorylation, the addition of P-H or P(O)-H bonds to unsaturated substrates is a particularly attractive approach since its 100% atom economical yield. So far, many transition metal-catalyzed reactions have been reported, such as the addition of phosphine oxide to CvC and CuC bonds.…”