Gold catalyzed intramolecular hydroalkoxylation assisted ring opening of furans to the corresponding saturated γ-keto esters

Transition Metal‐Catalyzed Hydroalkoxylation of Alkynes: An Overview

“…Prasad et al reported hydroalkoxylation-assisted reaction of alkynol-tethered furfuryl alcohol 101 for the synthesis of γ-keto esters 102 (Scheme 41). [46] Various γ-keto esters were synthe- Pt-catalyzed intramolecular 5-endo-dig hydroalkoxylationheterocyclization cascade was developed by Ferreira et al for the stereoselective synthesis of vicinal-fused heterocycles 103 in good to excellent yield and moderate diastereoselectivity from diols 104 (Scheme 42). [47] The developed method gave rapid access to 5/5, 5/6, and 5/7-fused vicinal heterocycles in excellent yield.…”

Platinum Single Atoms on Carbon Nanotubes as Efficient Catalyst for Hydroalkoxylation

“…[7][8][9][10][11] Among them, in particular, the gold(I)-catalyzed intramolecular hydroalkoxylation has drawn extensive interest owing to the potential for both stereospecific and enantioselective transformations. [12][13][14] Also, Pt catalysts are introduced for the hydroalkoxylation of direct intramolecular insertion of oxygen, exhibiting better activity and selectivity than Au catalysts, [15][16][17] since oxo-philic early-and middle-transition metals as well as Pt metal have strong binding with O-donor ligand and compound containing oxygen. In this paper, we report single Pt atoms on thiolated multiwalled carbon nanotubes (S-MWNTs) to maximize active surface area of catalyst for intramolecular hydroalkoxylation.…”