“…Quinoline is one of the most studied heterocycles, − and compounds containing this core are widely represented in natural products, , functional materials, and commercial drugs. , In particular, quinolines bearing sulfonyl substituents at position 3 have recently attracted a significant amount of attention as positron emission tomography radioligands, , agonists of metabotropic glutamate receptor type 5, − and antagonists of the 5-HT 6 receptor; therefore, 3-sulfonylquinolines can be used as promising drugs against different central nervous system disorders and/or diseases, including depression, anxiety, schizophrenia, etc. Structurally related 3-sulfamoylquinolines exhibit anti-breast cancer properties comparable to those of cisplatin.…”