Non-Friedländer Route to Diversely 3-Substituted Quinolines through Au(III)-Catalyzed Annulation Involving Electron-Deficient Alkynes

Advances in gold catalyzed synthesis of quinoid heteroaryls

“…The proposed mechanism suggests a dual role for the gold-catalyzed-based catalyst, activating both C–C bonds and carbonyl groups to facilitate hydroamination and subsequent cyclization. 111 …”

Copper-Catalyzed [4+1+1] Annulation of Ammonium Salts and Anthranils: Synthesis of 2,3-Diaroylquinolines

“…The development of synthetic strategies that efficiently construct diverse and complex molecules represents one of the most attractive and challenging issues in organic chemistry community, especially in constructing various bioactive heterocycles . In this regard, the utilization of onium ylides through annulation is a highly valuable approach to accessing heterocycles .…”