Glycosides of ergosterol derivatives from Hericum erinacens

Takaishi, Yoshihisa; Uda, Minoru; Ohashi, Takashi; Nakano, K.; Murakami, Koutarou; Tomimatsu, Toshiaki

doi:10.1016/0031-9422(91)83478-4

Cited by 79 publications

(48 citation statements)

References 12 publications

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“…The known isolates, i.e., xanthyletin (3) [50], umbelliferone (4) [51], scopoletin (5) [51], and (þ)-(S)-marmesin (6) [52], carpachromene (7) [53], parvisoflavone B (8) [54], alpinumisoflavone (9) [64], a mixture of 6b-hydroxystigmast-4-en-3-one (20) and 6b-hydroxystigmasta-4,22-dien-3-one (21) [65], a mixture of b-sitosterol (22) and stigmasterol (23) [66], and oleanolic acid (24) [67], were readily identified based on the data from the literature.…”

Section: Secondary Metabolites and Antimycobacterial Activities From mentioning

confidence: 99%

Secondary Metabolites and Antimycobacterial Activities from the Roots of Ficus nervosa

Chen

Cheng

Peng

et al. 2010

Chemistry & Biodiversity

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Bioassay-guided fractionation of the active AcOEt-soluble layer led to the isolation of two new pyranocoumarins, 3-hydroxyxanthyletin (1) and 3-methoxyxanthyletin (2), along with 22 known compounds including four simple coumarins, i.e., xanthyletin (3), umbelliferone (4), scopoletin (5), and (+)-(S)-marmesin (6); nine flavonoids, i.e., carpachromene (7), parvisoflavone B (8), alpinumisoflavone (9) genistein (10), 2'-hydroxygenistein (11), prunetin (12), cajanin (13), apigenin (14), and (2S)-naringenin (15); three benzenoids, i.e., 4-hydroxybenzaldehyde (16), vanillin (17), and (S)-lasiodiplodin (18); five steroids, i.e., ergosterol peroxide (19), a mixture of 6beta-hydroxystigmast-4-en-3-one (20) and 6beta-hydroxystigmasta-4,22-dien-3-one (21), and a mixture of beta-sitosterol (22) and stigmasterol (23); and one triterpenoid, i.e., oleanolic acid (24) from the roots of Ficus nervosa. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR as well as MS analyses. Among these isolates, 3-hydroxyxanthyletin (1), genistein (10), prunetin (12), and (2S)-naringenin (15) showed antimycobacterial activities against Mycobacterium tuberculosis H(37)R(V) in vitro with MIC values of 16, 35, 30, and < or =2.8 microg/ml, respectively.

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Section: Secondary Metabolites and Antimycobacterial Activities From mentioning

confidence: 99%

Secondary Metabolites and Antimycobacterial Activities from the Roots of Ficus nervosa

Chen

Cheng

Peng

et al. 2010

Chemistry & Biodiversity

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“…(Yamabushitake in Japanese, Hericiaceae) are known as an edible mushroom. The constituents of H. erinaceum have been previously investigated and shown to contain aromatic compounds, [2][3][4][5] fatty acids, 6) sterols 7) and polysaccharides. 8) Some aromatic compounds, including hericenone A (3), were found to have significant cytotoxicity against HeLa cells 2) and stimulating activity of the synthesis of the nerve growth factor.…”

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confidence: 99%

Two New Aromatic Compounds from Hericium erinaceum (BULL.: FR.) PERS.

Yaoita

Danbara

Kikuchi

2005

CHEMICAL & PHARMACEUTICAL BULLETIN

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“…The known compounds, uracil (3) (21) and (22E,20S,24R)-5α,8α-epidioxyergosta-6,22-dien-3-β-ol (4) (22)(23)(24)(25)(26) were identified by comparing their spectral data with those reported. Lupeol (2) (27) and daucosterol (5) (28) were identified by their spectral data and by co-TLC and co-m.p.…”

Section: -O-methyl-β-d-glucopyranoside (1cmentioning

confidence: 99%

A new glucoceramide from the watermelon begonia, Pellionia repens

Luo

Liu

et al. 2004

Lipids

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A new glucoceramide named pellioniareside (1) was isolated from the aqueous ethanolic extract of whole plants of Pellionia repens, together with lupeol (2), uracil (3), (22E,20S,24R)‐5α,8α‐epidioxyergosta‐6,22‐dien‐3‐β‐ol (4), and daucosterol (5). The structure and relative configurations of pellioniareside were identified as (2S,3S,4R,6E,8E)‐1‐O‐β‐d‐glucopyranosyl‐2‐[(2R)‐2‐hydroxytetracosanoylamino]‐1,3,4‐octadecanetriol‐6,8‐diene by analysis of spectral data and by chemical evidence.

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Glycosides of ergosterol derivatives from Hericum erinacens

Cited by 79 publications

References 12 publications

Secondary Metabolites and Antimycobacterial Activities from the Roots of Ficus nervosa

Secondary Metabolites and Antimycobacterial Activities from the Roots of Ficus nervosa

Two New Aromatic Compounds from Hericium erinaceum (BULL.: FR.) PERS.

A new glucoceramide from the watermelon begonia, Pellionia repens

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