A new glucoceramide from the watermelon begonia, Pellionia repens

Abstract

A new glucoceramide named pellioniareside (1) was isolated from the aqueous ethanolic extract of whole plants of Pellionia repens, together with lupeol (2), uracil (3), (22E,20S,24R)‐5α,8α‐epidioxyergosta‐6,22‐dien‐3‐β‐ol (4), and daucosterol (5). The structure and relative configurations of pellioniareside were identified as (2S,3S,4R,6E,8E)‐1‐O‐β‐d‐glucopyranosyl‐2‐[(2R)‐2‐hydroxytetracosanoylamino]‐1,3,4‐octadecanetriol‐6,8‐diene by analysis of spectral data and by chemical evidence.

Screening for Vietnamese Plant Extracts With Potential Benefit for Anti Osteoclastogenesish

“…Previous study showed that lupeol -one of the chief components of Pellionia repens (Lour.) Merr (S70) [15], Cratoxylum cochinchinense (Lour.) Blume (S47) [16], and Bombax ceiba L. (S16) [17] exhibits strong inhibitory effects on osteoclastogenesis [18].…”

Pelliolatifolias A‐D, Four Undescribed Compounds from Pellionia latifolia Boerl. and Their Nitric Oxide Production Inhibitory Activity

“…Some Pellionia plants are used in folk medicine to treat some liver diseases, detoxify the liver, and reduce cholesterol [1] . The previous studies have found that the chemical constituents of the Pellionia genus were amides, triterpenoids, steroids, and other composition [2,3] . In our study program to find anti‐inflammatory activity components from Vietnamese plants, the MeOH extract of Pellionia latifolia showed good NO production inhibition with IC 50 value of 35.7 μg/mL, and therefore was chosen for further study.…”

“…[1] The previous studies have found that the chemical constituents of the Pellionia genus were amides, triterpenoids, steroids, and other composition. [2,3] In our study program to find anti-inflammatory activity components from Vietnamese plants, the MeOH extract of Pellionia latifolia showed good NO production inhibition with IC 50 value of 35.7 μg/mL, and therefore was chosen for further study. This article described three new phenylalanine derivatives (1)(2)(3), a new 2-arylbenzofuran derivative (4), and seven known compounds (5)(6)(7)(8)(9)(10)(11) from the leaves of P. latifolia and their NO inhibitory activity in LPS-activated RAW264.7 cells in vitro.…”