Glycoprotein synthesis by the perfused livers from normal and tumour-bearing rats.

Burston, D.; Apsey, M. E.

doi:10.1038/bjc.1967.94

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Basic Characteristics Of the Liver1

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1969

1974

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Cited by 7 publications

(2 citation statements)

References 8 publications

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“…Similar findings were observed by other authors [7,8,34, 35j although Fisher [15] did not observe any change in liver glycogen.…”

Section: Discussionsupporting

confidence: 91%

A Versatile Method for the <i>in vitro</i> Perfusion of Isolated Organs of Rats and Mice with Particular Reference to Liver

Kvĕtina

Guaitani²

1969

Pharmacology

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“…Similar findings were observed by other authors [7,8,34, 35j although Fisher [15] did not observe any change in liver glycogen.…”

Section: Discussionsupporting

confidence: 91%

A Versatile Method for the <i>in vitro</i> Perfusion of Isolated Organs of Rats and Mice with Particular Reference to Liver

Kvĕtina

Guaitani²

1969

Pharmacology

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“…It represents the most significant change. Similar findings were observed by Brauer et al (1951) Burston andApsey (1967), Penthos et al (1966 a, b,) and Kvgtina and Guaitani (1969). Bloxam (1971) found that 95 % of the liver glycogen had been lost already during the operation and transfer of the liver.…”

Section: Basic Characteristics Of the Liversupporting

confidence: 87%

Synthesis of Serum Albumin in Isolated Rat Liver Perfused by a Synthetic Medium with Fluorocarbon FG–80 Emulsion as Oxygen Carrier

Nováková

Plantin

1974

Acta Physiologica Scandinavica

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A fluorocarbon emulsion FC‐80 has been used as a substitute for erythrocytes in a synthetic nutrition medium in in vitro perfusions of isolated rat livers. The rate of albumin synthesis was estimated. After the first hour albumin was synthesised at a constant rate of 0.52 + 0.17 mg/h per 100 g of the body weight of the liver donor. 14C‐lysine was incorporated into the circulating proteins linearly after the first hour. Other parameters tested were: levels of circulating proteins, urea nitrogen, glucose, glutamic‐pyruvic transaminase, excretion of bile, weight changes of the liver, and level of glycogen in liver tissue after perfusion. Histological examinations were also performed. The function of the liver was comparable with the findings of other investigators who used whole blood as the perfusate. As far as we are aware this is the first time that a rat liver has been maintained in good functional condition for over 6 hours during in vitro perfusions with a synthetic medium that included an erythrocyte substitute. The method seems to offer great advantages for the study of metabolic processes.

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l-Glutamine:d-fructose 6-phosphate amidotransferase in tumors and the liver of tumor-bearing animals

Kikuchi

Kobayashi

Tsuiki

1971

Biochimica et Biophysica Acta (BBA) - General Subjects

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Glycoprotein synthesis by the perfused livers from normal and tumour-bearing rats.

Cited by 7 publications

References 8 publications

A Versatile Method for the <i>in vitro</i> Perfusion of Isolated Organs of Rats and Mice with Particular Reference to Liver

A Versatile Method for the <i>in vitro</i> Perfusion of Isolated Organs of Rats and Mice with Particular Reference to Liver

Synthesis of Serum Albumin in Isolated Rat Liver Perfused by a Synthetic Medium with Fluorocarbon FG–80 Emulsion as Oxygen Carrier

l-Glutamine:d-fructose 6-phosphate amidotransferase in tumors and the liver of tumor-bearing animals

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