Glycerol as a recyclable solvent for copper-catalyzed cross-coupling reactions of diaryl diselenides with aryl boronic acids

Glycerol as Suitable Solvent for the Synthesis of Metallic Species and Catalysis

“…CuI catalyzed the cross‐coupling reaction of diaryl‐diselenides with aryl boronic acids to give the corresponding diaryl‐selenides, using DMSO as additive (Scheme ). The catalytic phase could be reused up to four times without showing significant decreases in yield 31. The use of vinyl bromides instead of aryl boronic acids in the presence of Zn was also tested for this type of coupling 32…”

Catalysis in glycerol: a survey of recent advances

“…A higher yield (95 %) was achieved in 4 h when zinc dust was added to the reaction mixture: the resulting glycerol/CuI/Zn could then be recovered and reused in other reactions. A similar procedure was applied by Ricordi et al (2012) to evaluate whether glycerol was an efficient solvent for the cross-coupling reactions of diaryl diselenides with aryl boronic acids bearing electronwithdrawing and electron-donating groups (Fig. 29).…”

Bis(2-pyridyl)diselenoethers as versatile ligands for copper-catalyzed C–S bond formation in glycerol

“…12 On the other hand, the development of green methodologies from renewable resources has grown because of the extensive use of solvents in chemical industries and the impact of these on the environment, health and safety. 13 Glycerol, an organic waste generated by the biodiesel industry, has been recently proposed by Gu and Jérôme as a valuable green solvent. 14 The current availability of glycerol on a large scale and low cost, combined with its intrinsic properties, i.e.…”