Glycaemia dynamics concepts before and after insulin

Sobrevía, Luis

doi:10.1016/j.bcp.2022.115092

Cited by 5 publications

(4 citation statements)

References 101 publications

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“…Environmental factors may increase the susceptibility of pregnant women to be infected by SARS-CoV-2, including pre-pregnancy obesity —expected as non-stop increasing for 2030 according to the World Obesity Federation 2022 report [170] , diabetes mellitus, hypertension, nutrition habits, air, food, and water contaminants. These factors are considered part of the ecto -exposome and endo -exposome [136] , [171] to which pregnant women, their fetuses, and newborns are exposed. Also, it will be necessary to explore the effect of mass vaccination on infection during pregnancy and the newborn.…”

Section: Concluding Thoughts and Future Directionsmentioning

confidence: 99%

Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate

Carvajal

Casanello

Farías

et al. 2023

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Diseas

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Section: Concluding Thoughts and Future Directionsmentioning

confidence: 99%

Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate

Carvajal

Casanello

Farías

et al. 2023

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Diseas

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“…ESRD and hemodialysis exert opposing forces on insulin secretion, action, and metabolism, often creating unpredictable serum glucose values (Sobrevia, 2022). A patient who has IR would need more supplemental insulin; however, the reduced renal gluconeogenesis and insulin clearance seen in ESRD may result in variable net effects in different patients.…”

Section: -Insulin In Esrdmentioning

confidence: 99%

Insulin Resistance in End-Stage Renal Disease Patients: A Review

Twaij

Al‐Hakeim

2023

Egyptian Academic Journal of Biological Sciences. C, Physiology

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Many studies have found effects on the body and active products insulin state at near and long-term parameters in end-stage renal disease (ESRD) patients. Consequently, studying chemical molecules that cause tissue damage to kidneys is essential for understanding the mechanism of effect and available treatment prospects. Which includes some factors of insulin, Homeostasis Model Assessment insulin sensitivity (HOMA2%IR), Homeostasis Model Assessment sensitivity for cell (HOMA2%S), Homeostasis Model Assessment state beta cell function (HOMA2%B) parameters. The published papers on changes in the effects of IR products of patients were reviewed, and the explanations obtained from previous research were collected. It is concluded from this review that causes an increase in parameters in patients with ESRD leads to neurodegeneration and disorders affect the beta cell to produce insulin, which leads to severe damage to patients health that requires therapeutic intervention to reduce the harmful effects of parameters on the health of patients.

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“…However, not only elevated or decreased level of specific metabolites as factors of the exposome is determinant, but changes in a defined period delineating a dynamic (v.g. glycaemia dynamics in patients with diabetes mellitus) (Valero et al, 2022b) and its consequences in the regulation of internal homeostasis (Sobrevia, 2022) are conditions that deserve to be considered. High-resolution metabolomics and omics integration tools enable studies to connect function to environmental exposures at a population level.…”

Section: Fundingmentioning

confidence: 99%