Gluten-Free Diet and Lipid Profile in Children with Celiac Disease

Forchielli, Maria Luisa; Fernicola, Paola; Diani, Lucia; Scrivo, Barbara; Salfi, Nunzio; Pessina, Achille C.; Lima, Mario; Ministeri, S; Ballarini, E; Ragni, Maria Chiara; Pession, Andrea

doi:10.14309/00000434-201410002-02015

Cited by 4 publications

(3 citation statements)

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“…Although we found that total cholesterol and triglyceride levels in tTG-IgA positive patients were significantly lower than those of tTG-IgA negative patients, we cannot certainly comment on the effect of gluten-free diet on the cardiovascular profile because of the similarity of the cIMT and EATT measures and lipid profile of within normal range in tTG-IgA negative and positive patients. Previous studies suggested that treatment with a gluten-free diet led to the improvement of the imbalanced lipid profile of CD patients 33,34 . In addition to this, based on our findings, we suggest that treatment with a gluten-free diet may lead to the improvement of the imbalanced vitamin D and bone mineral, and ultimately atherosclerotic profiles.…”

Section: Discussionmentioning

confidence: 99%

Çölyak hastalığı olan çocuklar ile sağlıklı yaşıtlarının erken ateroskleroz belirteçlerinin karşılaştırılması

Karpuz

Tezol

Türkegün

et al. 2022

Cukurova Medical Journal

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Purpose: We aimed to evaluate carotid intima-media thickness (cIMT) and epicardial adipose tissue thickness (EATT) concurrently as early atherosclerotic markers in pediatric patients with Celiac disease. Materials and Methods: Patients with Celiac disease (n=54) and healthy peers (n=54) aged 5-18 years were enrolled in this cross-sectional study. Patients who followed gluten free diet at least the past 12 months were included. Anthropometric and biochemical measurements were performed. cIMT and EATT were measured by echocardiography and compared between the patient and control groups. Results: Body mass index (17.4±3.0 vs. 18.4±3.1 kg/m2), blood pressure (systolic: 100 (85-120) vs. 100 (80-100) mmHg; diastolic: 60 (40-90) vs. 70 (40-90) mmHg), and lipid profile (total cholesterol: 144.6±30.2 vs. 150.8±22.6 mg/dL; triglycerides: 71.5 (27-178) vs. 92.5 (34-203) mg/dL) were not different between the patient and control groups, while there were significant differences in cIMT and EATT. The patient group had higher cIMT (0.50±0.07 vs. 0.45±0.04 mm) and EATT (5.68±0.90 vs. 4.22±0.76 mm) than the control group. The risk of vitamin D insufficiency was 2.68 times higher in the patient group (95% CI=1.19-6.03). Conclusions: Children with Celiac disease had higher cIMT and EATT than healthy peers. cIMT and/or EATT measurements by echocardiography may present as a reliable and easy method to investigate subclinical atherosclerosis in children with Celiac disease.

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Section: Discussionmentioning

confidence: 99%

Çölyak hastalığı olan çocuklar ile sağlıklı yaşıtlarının erken ateroskleroz belirteçlerinin karşılaştırılması

Karpuz

Tezol

Türkegün

et al. 2022

Cukurova Medical Journal

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“…The dietary pattern of celiac people on GFD in published works indicate that even though energy consumption can adjust to energy waste, macronutrient distribution is not balanced. Protein and lipids (especially saturated ones) are usually consumed in excess among people following a GFD, and by contrast, carbohydrate consumption is low [5,6,70,71]. It has to be considered that GFP have partly been blamed for this imbalance, for several reasons: the high price of GFP (source of carbohydrates) that make celiac sufferers avoid them [72]; cereals used in GFP manufacturing that are poorer in proteins and usually not whole grains [19,73]; the use of fats and gums in their production in order to improve palatability [19], etc.…”

Section: Discussionmentioning

confidence: 99%

One-year follow-up of the nutritional status of celiac people on a gluten-free diet

Perez-Junkera

Vázquez-Polo

Eizagirre

et al. 2021

Preprint

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Background The gluten-free diet (GFD), the only effective treatment for celiac disease, is usually nutritionally imbalanced. The present work aimed to analyze the evolution of the nutritional status, dietary profile, and symptoms present among celiac people over one year on a GFD while receiving individualized dietary advice. Methods Twenty-seven adults and thirty-one celiac children/adolescents participated in the cohort study. They were followed by 3 visits, at diagnosis (vt0) and after 3 and 12 months (vt3;vt12). Participants filled out dietary and gastrointestinal symptoms questionnaires and received a personalized form from dietitians containing dietary advice and anthropometric and biochemical data evolution. Results Most patients presented normal BMI, fat and muscle mass, and biochemical parameters at diagnosis and vt12. By contrast, all participants consumed protein and lipids in excess and carbohydrates in defect, in both vt0 and vt12. Low intakes of cereals, fruits and vegetables and high of meat were observed, these also remain-ing unchanged after dietary counseling. Symptoms present decreased after vt3 but rebounded in vt12. Conclusions Few changes in dietary pattern and symptom elimination suggested that the intervention was not effective enough. More research is necessary to evaluate whether closer follow up and face-to-face dietary advice improve dietary habits of celiac people. Trial registration: Code PI2016069, Ethical Comitee of the Clinical Investigation of the Basque Country. Registered on 15 July 2016.

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“…corn starch, potato flour/starch and tapioca flour/starch [66] . According to recent research, patients with CD have high serum cholesterol and an increasing body mass [68] . GFP are likely to be a significant part of their diets, since they are removing staple foods such as bread or pasta.…”

Section: Nutritional Profile Of Gluten Containing and Gluten-free Foo...mentioning

confidence: 99%

Celiac disease: An epidemiological condition: Insight on gluten free diet, significance and regulatory recommendations

Kumari¹,

Morya²

2021

Pharma Innovation

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Celiac disease (CD) is a chronic small intestinal immune-mediated enteropathy due to exposure to dietary gluten in genetically vulnerable people. Enteropathy associated to the CD contributes to several macroand micronutrient-related nutrient failures. Celiac disease remains underdiagnosed in several regions, which can result in severe health issues. Non-invasive and inexpensive ways, such as video capsule endoscopy, are currently used for the diagnosis of celiac disease. The aim of this paper is to safe cure for CD by excluding the gluten from the diet, and providing gluten free diet (GFD) according to regulatory recommendations. The diet must not only be free of gluten, but must also be nutritious in order to avoid nutrient, vitamin and mineral deficiency or excess. Hence, we included the GFD, DASH (Dietary Stop Hypertension Appropriations), balanced kidney diet, ketogenic diatribe and low-FODMAP (Fermentable Oligo-, Di-, Mono-saccharides and Polyols) diet, which are forms of medically trained diets. Latest analysis shows that both recently diagnosed and post-GFD CD patients also have nutritional deficiencies. The results of this study reveal the value of a nutritionally healthy diet plan as part of CD treatment. Since celiac disease is a chronic disorder with a variety of symptoms that can be successfully diagnosed and treated to avoid both acute and long-term consequences, it can educate regular clinical practise in all medical disciplines. Patients should live on a completely GFD. A healthy GFD should be focused on a mixture of naturally gluten-free foods and certified gluten-free processed items.

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Gluten-Free Diet and Lipid Profile in Children with Celiac Disease

Cited by 4 publications

References 0 publications

Çölyak hastalığı olan çocuklar ile sağlıklı yaşıtlarının erken ateroskleroz belirteçlerinin karşılaştırılması

Çölyak hastalığı olan çocuklar ile sağlıklı yaşıtlarının erken ateroskleroz belirteçlerinin karşılaştırılması

One-year follow-up of the nutritional status of celiac people on a gluten-free diet

Celiac disease: An epidemiological condition: Insight on gluten free diet, significance and regulatory recommendations

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