Glucose-responsive hydrogel electrode for biocompatible glucose transistor

Kajisa, Taira; Sakata, Toshiya

doi:10.1080/14686996.2016.1257344

Cited by 56 publications

(45 citation statements)

References 31 publications

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“…Kajisa and Sakata fabricated a biocompatible glucose sensor through self-assembly of a functionalized hydrogel on the surface of semiconductor-based FET [245]. The hydrogel parts were prepared by copolymerization of glucose-sensitive vinylphenylboronic acid and biocompatible 2-hydroxyethylmethacrylate as monomer components.…”

Section: Thin Filmsmentioning

confidence: 99%

Self-assembly as a key player for materials nanoarchitectonics

Ariga

Nishikawa

Mori

et al. 2019

Science and Technology of Advanced Materials

354

255

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The development of science and technology of advanced materials using nanoscale units can be conducted by a novel concept involving combination of nanotechnology methodology with various research disciplines, especially supramolecular chemistry. The novel concept is called 'nanoarchitectonics' where self-assembly processes are crucial in many cases involving a wide range of component materials. This review of self-assembly processes reexamines recent progress in materials nanoarchitectonics. It is composed of three main sections: (1) the first short section describes typical examples of self-assembly research to outline the matters discussed in this review; (2) the second section summarizes self-assemblies at interfaces from general viewpoints; and (3) the final section is focused on self-assembly processes at interfaces. The examples presented demonstrate the strikingly wide range of possibilities and future potential of self-assembly processes and their important contribution to materials nanoarchitectonics. The research examples described in this review cover variously structured objects including molecular machines, molecular receptors, molecular pliers, molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nanoflakes, nanocubes, nanodisks, nanoring, block copolymers, hyperbranched polymers, supramolecular polymers, supramolecular gels, liquid crystals, Langmuir monolayers, Langmuir-Blodgett films, self-assembled monolayers, thin films, layer-by-layer structures, breath figure motif structures, two-dimensional molecular patterns, fullerene crystals, metal-organic frameworks, coordination polymers, coordination capsules, porous carbon spheres, mesoporous materials, polynuclear catalysts, DNA origamis, transmembrane channels, peptide conjugates, and vesicles, as well as functional materials for sensing, surface-enhanced Raman spectroscopy, photovoltaics, charge transport, excitation energy transfer, lightharvesting, photocatalysts, field effect transistors, logic gates, organic semiconductors, thin-film-based devices, drug delivery, cell culture, supramolecular differentiation, molecular recognition, molecular tuning, and hand-operating (hand-operated) nanotechnology.

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Section: Thin Filmsmentioning

confidence: 99%

Self-assembly as a key player for materials nanoarchitectonics

Ariga

Nishikawa

Mori

et al. 2019

Science and Technology of Advanced Materials

354

255

View full text Add to dashboard Cite

show abstract

“…This is because such MN-based electrode sensors are compatible not with complicated measurement systems but with relatively simple sensing principle such as electrochemical reactions at the surface of MNs. The limited measurement methodology, using only electrochemical sensing with conventional electrodes, restricts the use of more accurate methods of measurements such as FET-based sensors [ 116 – 118 ], which results in a limited number of measurable biomarkers.…”

Section: Towards Cgms Using Mnsmentioning

confidence: 99%

Functionalized microneedles for continuous glucose monitoring

Takeuchi

Kim

2018

Nano Convergence

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Microneedles (MNs) have been established as promising medical devices as they are minimally invasive, cause less pain, and can be utilized for self-administration of drugs by patients. There has been rapid development in MNs for transdermal monitoring and diagnostic systems, following the active research on fabrication methods and applications for drug delivery. In this paper, recent investigations on bio-sensing using MNs are reviewed in terms of the applicability to continuous glucose monitoring system (CGMS), which is one of the main research focuses of medical engineering technologies. The trend of the functionalized MNs can be categorized as follows: (i) as a sensing probe, and (ii) as a biological fluid collector. MNs as in vivo sensors are mainly integrated or coated with conductive materials to have the function as electrodes. MNs as fluid collectors are given a certain geometrical design, such as a hollow and porous structure aided by a capillary action or negative pressure, to extract the interstitial fluids or blood for ex vivo analysis. For realization of CGMS with MNs, a long-term accurate measurement by the MN-based sensing probe or a fluidic connection between the MN-based fluid collector and the existing microfluidic measurement systems should be investigated.

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“…Later, they incorporated a dual sensor strategy consisting of activated and deactivated GOx to minimize the interference effect (32). Kajisa et al (33) developed a highly sensitive hydrogel field effect transistor (FET) glucose sensor electrode suitable for use as a tear-based wearable device. The sensor electrode can significantly suppress the signal noise caused by nonspecific adsorption.…”

Section: Contact Lens-based Sensorsmentioning

confidence: 99%

Lab on the eye: A review of tear-based wearable devices for medical use and health management

Lan

Yang

2019

BST

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Wearable sensors have garnered considerable interest because of their great promise in terms of personalized health and disease management. Tears are a superior target for wireless, non-invasive wearable devices, and tear-based platforms have developed rapidly over the past decade. Although an increasing number of tear analytes have been found to be associated with multiple diseases, glucose still serves as a main target for tearbased wearable devices. There has been much investment and efforts to develop tearbased wearable biosensors, with contact lens-based and spring-like sensors flourishing commercially. Current efforts have moved past ocular and systematic disease markers to nutrients and chemicals. Moreover, tear-based wearable devices also have the potential to treat some ocular diseases. This review discusses aspects of tear-based wearable devices and it emphasizes that strict clinical validation is needed before such platforms enter the market. Multifunctional and theranostic strategies would further broaden their clinical use in the future.

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Glucose-responsive hydrogel electrode for biocompatible glucose transistor

Cited by 56 publications

References 31 publications

Self-assembly as a key player for materials nanoarchitectonics

Self-assembly as a key player for materials nanoarchitectonics

Functionalized microneedles for continuous glucose monitoring

Lab on the eye: A review of tear-based wearable devices for medical use and health management

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