Glucose Detection Characteristics of an Extended-Gate Field-Effect Transistor Fabricated by the Enzyme Immobilization Using a Long-Chain-Aminosilane Agent

Koike, Kazuto; Onishi, Yusuke; Ike, Kodai; Hirofuji, Yuichi; Nakamura, Yoshinobu; Yano, Mitsuaki

doi:10.1541/ieejsmas.139.143

Cited by 3 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To immobilize GOD on the ion-sensitive gate electrode, ionic binding, covalent binding, and inclusion methods have been developed. Among them, the covalent bonding method is mostly used for ISFET-type and EGFET-type biosensors, similar to the cases of our ZnO-based ISFET-type [15,16] and EGFET-type glucose sensors [21]. Although the number is limited, however, the inclusion method is also applied as reported by You et al [22].…”

Section: Introductionmentioning

confidence: 78%

“…To check the sensitivity of the EGFET-type ion/glucose sensors, the experimental setup shown in Figure 1 [21] was employed, where the electrolyte was 100 mM PBS. The extended gate electrode was immersed in the electrolyte and connected with the gate electrode of an outside MOSFET.…”

Section: Device Setup and Measuring Conditions Used For Ph And Glucosmentioning

confidence: 99%

“…To measure the pH sensitivity of the EGFET-type ion sensors, the electrolyte was kept at 25 • C; the pH was controlled at 6.1, 6.6, 7.0, and 7.5 [21] by changing the mixing ratio of the commercially available PBS reagents at pH = 8.0, 7.0, and 6.0; and the pH was controlled at 5.5 by mixing sodium dihydrogenphosphate dehydrate with the PBS reagent at pH = 6.0. To measure the glucose sensitivity, on the other hand, a specific quantity of β-D glucose powder was dissolved in 100 mM PBS at pH = 6.0, and the solution during the measurement was kept at 37 • C to activate the enzymatic function at around the optimal condition.…”

Section: Device Setup and Measuring Conditions Used For Ph And Glucosmentioning

confidence: 99%

“…The surface modification of the TiO 2 /Ti extended gate electrode was performed by the following silanization process using a silane coupling treatment [21,28]:…”

Section: Modification Process For the Tio 2 Surface And Preparation Pmentioning

confidence: 99%

“…Apart from these ISFET-type biosensors, Spiegel et al [17] developed in 1983 a new FET-type ion sensor named extended gate FETs (EGFETs) by connecting an ion-sensitive extended electrode to the gated electrode of a commercially available metal-oxide-semiconductor FET (MOSFET). Since EGFETs do not require a specialized solution gate like ISFETs and can be used repeatedly by replacing the extended gate electrodes, their application to biosensors [18][19][20][21] is a current study of interest.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Characteristics of an Extended Gate Field-Effect Transistor for Glucose Sensing Using an Enzyme-Containing Silk Fibroin Membrane as the Bio-Chemical Component

et al. 2020

Self Cite

View full text Add to dashboard Cite

The characteristics of a glucose sensor based on an ion-sensitive TiO2/Ti extended gate electrode field-effect transistor (EGFET) are reported. A glucose oxidase-containing silk fibroin membrane was immobilized on a TiO2/Ti surface as the bio-sensing component. This EGFET-type biosensor was estimated to be able to detect a glucose concentration as low as 0.001 mg/mL in an aqueous electrolyte, which enables the sensing of glucose in the saliva and sweat. The endurance of this sensor was also examined, and it was found that the retention time of the original sensitivity for repeated use at room temperature was more than 30 days, with a high heat tolerance temperature close to 60 °C.

show abstract

Section: Introductionmentioning

confidence: 78%

Section: Device Setup and Measuring Conditions Used For Ph And Glucosmentioning

confidence: 99%

Section: Device Setup and Measuring Conditions Used For Ph And Glucosmentioning

confidence: 99%

“…The surface modification of the TiO 2 /Ti extended gate electrode was performed by the following silanization process using a silane coupling treatment [21,28]:…”

Section: Modification Process For the Tio 2 Surface And Preparation Pmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Characteristics of an Extended Gate Field-Effect Transistor for Glucose Sensing Using an Enzyme-Containing Silk Fibroin Membrane as the Bio-Chemical Component

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

Fabrication of an Enzyme Membrane for Creatinine Detection and Its Application to an Extended-Gate FET-Based Biosensor

et al. 2023

View full text Add to dashboard Cite

Perspective of Semiconductor Technologies Contributed to the IoT Society

Koike

Yano

2020

J. Soc. Mat. Sci., Japan

View full text Add to dashboard Cite

Perspective of Semiconductor Technologies Contributed to the IoT Society 講座の開始にあたって人工知能(AI)として広く用いられている GPU(グラフィクス・プロセシング・ユニット)ボードの中には，ついに，人間の大脳皮質の神経細胞数 140 億個を超える 210 億個ものシリコントランジスタを搭載するものがでてきた．本来は神経細胞数ではなくシナプスの数で勘定すべきだが，素子数で言えば人間の大脳の規模に匹敵する集積回路を 100 万円で購入できる時代になったのである．このような半導体技術の進展により，AI やビッグデータが，いま，大きく花開いている．これからは，AI やビッグデータ，第５世代移動通信システム(5G)などからなるサイバー世界と，ロボットや電気自動車など物理法則が支配する物理世界の融合が進み，新しい価値が生まれると考えられている．これはサイバーフィジカルシステム(CPS)化とよばれる潮流である．このような潮流に沿って半導体技術の適用分野は広がり続けている． AI の発達にあわせて，末端の感覚器 (センサー) や情報を可視化するディスプレイの高度化や多機能化は必然である．これらの分野ではこれまでにない材料の組み合わせが花開きつつある．また，インターネットやクラウドコンピューティングを成り立たせているデータセンターの中での膨大な情報のやり取りは，大容量光ファイバー通信技術によって行われている．すでに，データセンターでの電力消費は全世界の電力消費の 1.3％に達している．現在の技術のまま，まったく省エネルギー対策がなされないと仮定すると，データセンターやネットワーク，エンドユーザでの情報処理や通信で消費される電力は 2030 年には世界全体で年間 42PWh(ペタワット時)となり，現在の世界の消費電力の約 24PWh を大きく上回ると予測されている．情報処理や通信，ロボット，電気自動車などにおける電力消費の高効率化は極めて重要な課題である．電力消費の高効率化を目指すパワーエレクトロ二クス分野でワイドギャップ半導体が重要な地位を築きつつある．今回，このような半導体材料やデバイスの最前線を紹介する以下のような 4 回の連載講座を企画した． 1. 電界効果トランジスターを用いたバイオセンサー小池一歩矢野満明(大阪工業大学) 2. 希土類添加半導体を用いた超狭帯域発光ダイオードとディスプレイ応用市川修平稲葉智宏塩見圭史館林潤 Dolf TIMMERMAN 藤原康文(大阪大学) 3. 界面顕微光応答法によるワイドバンドギャップ材料・電極界面の 2 次元評価塩島謙次(福井大学) 4. 光通信デバイスの最近の進展市野邦男(鳥取大学)

show abstract

Glucose Detection Characteristics of an Extended-Gate Field-Effect Transistor Fabricated by the Enzyme Immobilization Using a Long-Chain-Aminosilane Agent

Cited by 3 publications

References 8 publications

Characteristics of an Extended Gate Field-Effect Transistor for Glucose Sensing Using an Enzyme-Containing Silk Fibroin Membrane as the Bio-Chemical Component

Characteristics of an Extended Gate Field-Effect Transistor for Glucose Sensing Using an Enzyme-Containing Silk Fibroin Membrane as the Bio-Chemical Component

Fabrication of an Enzyme Membrane for Creatinine Detection and Its Application to an Extended-Gate FET-Based Biosensor

Perspective of Semiconductor Technologies Contributed to the IoT Society

Contact Info

Product

Resources

About