Glomerular filtration rate in the first three weeks of life

Guignard, Jean‐Pierre; Torrado, A.; Cunha, O. Da; Gautier, E

doi:10.1016/s0022-3476(75)80600-7

Cited by 203 publications

(71 citation statements)

References 13 publications

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“…Creatinine clearance was low at birth, the lowest values being observed in the most premature infants. This observation confirms data obtained from creatinine clearance studies (1, 2, 8-11) or, in a more accurate way, from inulin clearance studies (3,4,6,7). Although inulin remains the best glomerular marker, its measurement is not easy.…”

Section: P H M a Creatinine Concentrationsupporting

confidence: 89%

“…Abbreviations GFR, glomerular filtration rate BW, birth weight VLBW, very low birth weight GA, gestational age Renal function is low at birth, especially in the most premature infants (1)(2)(3)(4)(5). The functional maturation of the GFR after birth has been well documented in term neonates.…”

mentioning

confidence: 99%

“…The functional maturation of the GFR after birth has been well documented in term neonates. Studies using inulin (3,4,6,7) or creatinine (1,2,(8)(9)(10)(11)(12) as a glomerular marker have demonstrated a rapid increase in GFR in the neonatal period, with the value of inulin clearance actually doubling in the first 2 wk of life…”

mentioning

confidence: 99%

“…Thereafter, GFR reaches a plateau until the end of gestation, indicating that renal function and renal mass mature in parallel (4,14). As in term neonates, birth is followed by a rapid increase in inulin clearance during the first weeks of life (3,4). The velocity of the postnatal increase in inulin clearance is slightly inferior in premature neonates compared with term neonates, but the difference does not appear to be statistically significant (1,4,14).…”

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confidence: 99%

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Renal Function in Preterm Neonates

Guignard

1994

Pediatr Res

215

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The plasma creatinine concentration is elevated at birth and decreases concomitantly with the rapid increase in glomerular filtration rate that occurs in the first postnatal weeks. The velocity of these changes was assessed during the first 3 wk of life of 66 term and preterm infants. The plasma creatinine concentration, creatinine clearance, and sodium fractional excretion were measured serially at weekly intervals, starting 1-4 d after birth [mean = 1.5 -c 0.8 (SD) dl. Premature infants were separated into three groups according to their birth weight: group 1, 1001 to 1500 g; group 2, 1501 to 2000 g; and group 3, 2001 to 2500 g. Group 4 included 28 term infants (mean birth weight = 3165 ? 78 g). Mean gestational ages in the preterm groups were 31.3, 32.8, and 34.4 wk in groups 1, 2, and 3, respectively. The plasma creatinine concentration on d 1.

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Section: P H M a Creatinine Concentrationsupporting

confidence: 89%

mentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Renal Function in Preterm Neonates

Guignard

1994

Pediatr Res

215

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“…Inulin Preterm (n = 109) (references (6,(20)(21)(22)); term (n = 29) (21,22); children (4-11.3 years; n = 17) (17,18); adolescents (12-15 years; n = 14) (18,23,24); adults (19-49 years; n = 34 (19,23,24); total = 203 subjects CRCL preterm (n = 29) (25,26); term (n = 31) (14,25,26); infants (7-113 days; n = 12) (27); children (3.3-12 years; n = 21) (28-30); adolescents (13-17 years; n = 6) (29,30); adults (20-39 years; n = 33) (31-34); total = 132 subjects.…”

Section: Validation Of the Modelsmentioning

confidence: 99%

Prediction of Human Glomerular Filtration Rate from Preterm Neonates to Adults: Evaluation of Predictive Performance of Several Empirical Models

Mahmood

Staschen

2016

AAPS J

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Abstract. The objective of this study was to evaluate the predictive performance of several allometric empirical models (body weight dependent, age dependent, fixed exponent 0.75, a data-dependent single exponent, and maturation models) to predict glomerular filtration rate (GFR) in preterm and term neonates, infants, children, and adults without any renal disease. In this analysis, the models were developed from GFR data obtained from inulin clearance (preterm neonates to adults; n = 93) and the predictive performance of these models were evaluated in 335 subjects (preterm neonates to adults). The primary end point was the prediction of GFR from the empirical allometric models and the comparison of the predicted GFR with measured GFR. A prediction error within ±30% was considered acceptable. Overall, the predictive performance of the four models (BDE, ADE, and two maturation models) for the prediction of mean GFR was good across all age groups but the prediction of GFR in individual healthy subjects especially in neonates and infants was erratic and may be clinically unacceptable.

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Renal Response in Low-Birth-Weight Neonates

Stonestreet¹

1983

Am J Dis Child

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Glomerular filtration rate in the first three weeks of life

Cited by 203 publications

References 13 publications

Renal Function in Preterm Neonates

Renal Function in Preterm Neonates

Prediction of Human Glomerular Filtration Rate from Preterm Neonates to Adults: Evaluation of Predictive Performance of Several Empirical Models

Renal Response in Low-Birth-Weight Neonates

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