Glomangiopericytoma (sinonasal-type haemangiopericytoma)

Abstract

Glomangiopericytomas are rare, vascular, sinonasal tumours. Successful management depends on complete resection, traditionally achieved via an open approach. However, recent advances in endoscopic surgical approaches have enabled complete endoscopic resection of these tumours, minimising morbidity and facilitating subsequent surveillance of the operative site.

Glomangiopericytoma simulating an intracavernous meningioma

“…The first case involved the anterior skull base secondarily to glomangiopericytoma arising from the nasal and paranasal sinuses, while in the second case the glomangiopericytoma arose directly from the skull base region. [ 21 28 ] To the best of our knowledge, our patient is the first case of glomangiopericytoma localizing solely to the left cavernous sinus.…”

“…The tumor cells are strongly positive for actin and vimentin on immunohistochemical staining. [ 10 21 30 ] Occasionally, tumor cells are positive for SMA, laminin, factor XIIIa, MSA, and D2-40. [ 8 11 13 30 ] In addition, tumor cells are usually negative for S100, desmin, cytokeratin, Bcl-2, factor VIII, CD34, CD99, and CD117.…”

“…With the recent advancements in the endoscopic techniques, some authors consider endoscopic surgery as the modality of choice for tumors involving the sinonasal and anterior skull base regions. [ 21 ] The improved visualization of the tumor with endoscopic approaches allows for complete and safe resection of the tumor. In addition, endoscopic surgery is associated with better esthetic outcomes and fewer complication rates and hospital stay.…”

Characteristics and prognosis of glomangiopericytomas: A systematic review

“…After full‐text assessment, 139 articles were also excluded: articles containing no histologic findings (n = 20), unclear histology (n = 10), duplicate cases (n = 3), cases not arising in the sinonasal tract (n = 21), other sinonasal tumors, such as solitary fibrous tumor (n = 39), glomus tumor (n = 27), myopericytoma (n = 3), fibroma (n = 1), papilloma (n = 1), and lymphoma (n = 1), and reviews without information about individual cases (n = 13). Finally, 80 articles containing glomangiopericytoma of the sinonasal tract (337 cases) were identified as eligible for this study . Most articles (75/80; 94%) were published in English, except for 5 articles written in Korean …”

An unusual mass of nasal cavity: recurrent glomangiopericytoma

“…[2,3] 7.5 to 25% of all hemangiopericytoma are found in the head and neck region, especially in the nasal cavity and paranasal sinuses. [4] They have a significant pericytic vascular pattern with thin-walled, branching vessels often with a staghorn configuration. [2] Hemangiopericytoma-like lesions may also show similar histopathological patterns.…”