Global tests on coagulation and fibrinolysis in systemic and pulmonary circulation accompanying hip arthroplasty with acrylic cement

Dahl, Ola E.; Molnár, István; Rø, Johannes; Vinje, Arne

doi:10.1016/0049-3848(88)90346-5

Cited by 25 publications

(12 citation statements)

References 16 publications

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“…[1][2][3][4][5][6][7] Most of these series were of cemented prostheses; it is possible therefore that cement may have thrombogenic properties and so influence the incidence of DVT. Reports concerning this are conflicting; activation of the clotting cascade and concurrent fibrinolysis have been described during and after TKR and THR, 8,9 but it is uncertain whether this activation is different in cemented compared with uncemented prostheses. 10,11 Clotting investigations during operation have indicated that, at least for THR, both reaming of the medullary canal and cementing of the femoral stem can enhance coagulation, but that preparation and cementing of the acetabulum do not.…”

mentioning

confidence: 96%

Cement as a risk factor for deep-vein thrombosis

Clarke

Green

Harper

et al. 1998

The Journal of Bone and Joint Surgery. British volume

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A total of 110 total knee replacements (TKRs) was randomised to receive either a cemented or an uncemented prosthesis. Postoperative venography at five to seven days was used to compare the prevalence, site and size of deep-vein thrombosis (DVT). We also compared the findings with those of postoperative venography in a group of patients with cemented total hip replacements (THRs).The total prevalence of DVT was significantly greater after uncemented (81%) than after cemented TKR (55%). Both knee groups had a significantly higher prevalence of DVT than in cemented hip replacements (32%). We found no difference in the proportion with proximal DVT in the three groups (14%, 15% and 16%). The median length of the thrombi was significantly greater after cemented (26.5 cm) than after uncemented TKR (11 cm) or after cemented THR (7 cm). This difference was mainly due to greater lengths of distal rather than proximal thrombi.We conclude that the use of cement may affect the formation of DVT after joint replacement, but does not appear to lead to an increased incidence.

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mentioning

confidence: 96%

Cement as a risk factor for deep-vein thrombosis

Clarke

Green

Harper

et al. 1998

The Journal of Bone and Joint Surgery. British volume

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“…(1)(2)(3)(4)(5) Earlier studies reported a higher risk of DVT in cemented TKR and THR. (6)(7)(8)(9)(10) Several studies have also demonstrated thrombogenic properties of bone cement that may contribute towards the development of DVT. (15)(16)(17) In addition, the hypercoagulable state after a traumatic femoral neck fracture would put these patients at greater risk for thromboembolism.…”

Section: Discussionmentioning

confidence: 99%

“…(1)(2)(3)(4)(5) In earlier studies reported in the 1990s, the cemented prosthesis was associated with a higher incidence of deep vein thrombosis (DVT) in total knee replacements (TKR) and total hip replacements (THR). (6)(7)(8)(9)(10) Subsequent studies, however, provided contradictory results and there was a lack of new data thereafter. (11,12) Notably, all of these studies (6)(7)(8)(9)(10)(11)(12) used healthy patients for elective surgery, while patients with traumatic femoral neck fractures are potentially in a procoagulable state due to the nature of the trauma sustained in the initial injury.…”

Section: Introductionmentioning

confidence: 99%

“…(6)(7)(8)(9)(10) Subsequent studies, however, provided contradictory results and there was a lack of new data thereafter. (11,12) Notably, all of these studies (6)(7)(8)(9)(10)(11)(12) used healthy patients for elective surgery, while patients with traumatic femoral neck fractures are potentially in a procoagulable state due to the nature of the trauma sustained in the initial injury. (13,14) In addition, several recent studies have reported on the possible thrombogenic properties of polymethyl methacrylate cement and the activation of platelet aggregation and cytokines, which could contribute to the pathogenesis of DVT.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cemented hemiarthroplasty in traumatic displaced femoral neck fractures and deep vein thrombosis: is there really a link?

Hong¹,

Nashi²,

Makandura³

et al. 2016

smedj

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“…Die intra operative Letalitätsrate wird mit 0,6-10% angegeben [51,52]. Eine Erklärung hierfür ist, dass es während dieser Ein griffe zu einer Verschleppung von Mikro emboli in die pulmonale Strombahn kommt.…”

Section: Orthopädische Eingriffeunclassified

Intraoperative Echokardiographie

et al. 2009

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Since the introduction of intraoperative echocardiography into clinical practice in the 1970's its use and utility in the perioperative period has become increasingly more evident. Especially in patients undergoing cardiac surgical procedures intraoperative echocardiography has gained great diagnostic importance. Intraoperative transesophageal echocardiography (TEE) and epiaortic ultrasound are two important and complementing diagnostic modalities in this patient population. The clinical information obtained with intraoperative TEE in certain cases might have a direct impact on surgical decision-making and therefore may positively influence patient outcome. In patients undergoing non-cardiac surgical procedures, TEE can be a valuable tool in high-risk patients, in patients experiencing hemodynamic instability or in those suffering intraoperative cardiac arrest. Intraoperative TEE might allow a primary diagnosis of the underlying etiology and facilitate the institution of further therapeutic interventions. In addition TEE can be performed during ongoing cardiopulmonary resuscitation and does not interfere with patient management. This review introduces the clinician to the current evidence of the impact of intraoperative echocardiography on intraoperative surgical decisions during surgical procedures. It helps the clinician to identify indications and realize the potential applications of intraoperative echocardiography.

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Global tests on coagulation and fibrinolysis in systemic and pulmonary circulation accompanying hip arthroplasty with acrylic cement

Cited by 25 publications

References 16 publications

Cement as a risk factor for deep-vein thrombosis

Cement as a risk factor for deep-vein thrombosis

Cemented hemiarthroplasty in traumatic displaced femoral neck fractures and deep vein thrombosis: is there really a link?

Intraoperative Echokardiographie

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