Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

Abstract

BackgroundThe burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world.ObjectivesThe GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden.MethodsCVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility.ResultsIn 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an SDI >0.75.ConclusionsCVDs remain a major cause of health loss for all regions of the world. Sociodemographic change over the past 25 years has been associated with dramatic declines in CVD in regions with very high SDI, but only a gradual decrease or no change in most regions. Future updates of the GBD study can be used to guide policymakers who are focused on reducing the overall burden of noncommunicable disease and achieving specific global health targets for CVD.

Burden of Ischaemic heart disease and attributable risk factors in China from 1990 to 2015: findings from the global burden of disease 2015 study

“…Cardiovascular diseases (CVDs), which accounted for one-third of global deaths in 2015, are recognised as a major barrier to sustainable human development [1,2]. Of all CVDs, ischaemic heart disease (IHD) is one of the leading causes of mortality and disease burden worldwide [3], resulting in approximately 8.9 million deaths and 164.0 million disability-adjusted life years (DALYs) globally in 2015 [4][5][6].…”

An Integrative Boimarker: Opportunities for Non-Invasive Diagnostics of Coronary Atherosclerosis

“…Более чем в 50% случаев внезапная сердечная смерть или острый инфаркт миокарда являются первыми сим-птомами коронарной болезни сердца (КБС), т. е. про-исходят на субклинической стадии атеросклероза. Также около 20% всех сосудистых событий происхо-дит в отсутствие традиционных факторов риска, а половина из них -у лиц без выраженного наруше-ния липидного спектра [1,3,4].…”

Effect of meat product with onion skin extract on мetabolic profile in SHR

“…CVD are the leading cause of death globally, most occurred in low and middle income countries [1]. High prevalence of CVD is supported by rising amount of people with metabolic syndrome, consisting of obesity, arterial hypertension, lipid and glucose disorders.…”

“…High prevalence of CVD is supported by rising amount of people with metabolic syndrome, consisting of obesity, arterial hypertension, lipid and glucose disorders. According to WHO, CVD prevalence can be decreased by the influence on diet and body weight among others factors [1]. So nutrition researches and food industry need to search for the new product compositions to prevent and correct metabolic disorders.…”